Global Value Chain Embeddedness, Digital Economy and Green Innovation- Evidence From Provincial-Level Regions of China

With globalization and digitalization, participating in Global Value Chain (GVC) and developing digital economy have had a profound impact, which transforms China’s economy into a green and innovative one. This paper studies the intrinsic influential mechanism of GVC embeddedness and digital economy on green innovation and proposes some research hypotheses. Based on panel data of 30 Chinese provinces from 2002 to 2016, we constructed some core indicators such as GVC embeddedness, digital economy and green innovation. The ordinary panel model and spatial panel model are used to empirically test the impact of GVC embeddedness and digital economy on China’s green innovation at the provincial level. The research findings are: First, GVC embeddedness and digital economy have significant promotion effects on green innovation. Second, the development of digital economy will not only directly promote green innovation, but also indirectly promote green innovation by effectively promoting the integration of provincial economy into GVC. The results of mediating effect test show that GVC embeddedness has a partial mediating effect in the influential mechanism of digital economy to promote green innovation. Third, GVC embeddedness and green innovation have significant spatial spillover effects. It indicates that Chinese provinces (cities¹) have significantly promoted green innovation in neighboring provinces through many possible channels and mechanisms in the process of participating in GVC, and the robustness test shows the stability of the spatial spillover mechanism. The findings provide useful policy implications for China’s deeply participating in GVC, vigorously developing digital economy and promoting green innovation

Identity Authentication Security Management in Mobile Payment Systems

Mobile payment is a new payment method offering users mobility, reachability, compatibility, and convenience. But mobile payment involves great uncertainty and risk given its electronic and wireless nature. Therefore, biometric authentication has been adopted widely in mobile payment in recent years. However, although technology requirements for secure mobile payment have been met, standards and consistent requirements of user authentication in mobile payment are not available. The flow management of user authentication in mobile payment is still at its early stage. Accordingly, this paper proposes an anonymous authentication and management flow for mobile payment to support secure transaction to prevent the disclosure of users\u27 information and to reduce identity theft. The proposed management flow integrates transaction key generation, encryption and decryption, and matching to process users\u27 personal information and biometric characteristics based on mobile equipment authentication carrier

Effect of berbamine hydrochloride on the absorption of berberine hydrochloride in an in situ single-pass intestinal perfusion system in rats

Purpose: To investigate the intestinal absorption characteristics of berberine hydrochloride (BBH) under different perfusion conditions in rats.Methods: Based on the in situ single-pass intestinal perfusion model of rats, HPLC was used to determine the content of berberine hydrochloride in solution after perfusion under different conditions. The absorption rate constant (Ka), effective permeability coefficient (Papp) and cumulative absorption per unit area (Q) under different perfusion conditions were analyzed by one-way ANOVA.Results: The Papp and Ka of BBH in perfusion solution at pH 7.4 were greater than those in perfusion solution at pH 6 and 8. There was no significant difference (p > 0.05) in Papp and Ka of duodenum, jejunum and ileum at high, medium and low concentrations of berberine hydrochloride perfusion solution. The Q increased linearly with increase of mass concentration of perfusion solution. The Ka and Papp of BBH in duodenum, jejunum, and ileum of BBH and berbamine hydrochloride (BAH) combined at different ratios were higher than those of BBH control group at the same BBH concentration, but absorption of BBH in the ratio B40:A50 and B30:A20 groups was highest. In the ratio of B40:A50 ratio, B30:A20 ratio group or the same concentration's BBH group, Ka and Papp of BBH decreased in the order of jejunum > duodenum > ileum.Conclusion: Berberine hydrochloride is absorbed in neutral environment of pH 7.4. The intestinal absorption mechanism of BBH is passive diffusion, and jejunum is the best intestinal segment for absorption. BAH promotes the absorption of BBH

A Track Initiation Method for FM-based Passive Radar Network Based on Multiple Elementary Hypotheses

Passive radars based on FM radio signals have low detection probability, high false alarm rates and poor accuracy, presenting considerable challenges to target tracking in radar networks. Moreover, a high false alarm rate increases the computational burden and puts forward high requirements for the real-time performance of networking algorithms. In addition, low detection probability and poor azimuth accuracy result in a lack of redundant information, making measurement association and track initiation challenging. To address these issues, this paper proposes an FM-based passive radar network based on the concepts of elementary hypothesis points and elementary hypothesis track, as well as a track initiation algorithm. First, we construct possible low-dimensional association hypotheses and solve for their corresponding elementary hypothesis points. Subsequently, we associate elementary hypothesis points from different frames to form multiple possible elementary hypothesis tracks. Finally, by combining multi-frame radar network data for hypothesis track judgment, we confirm the elementary hypothesis tracks corresponding to the real targets, and eliminate the false elementary hypothesis tracks caused by incorrect associations. Result reveal that the proposed algorithm has lower computational complexity and faster track initiation speed than existing algorithms. Moreover, we verified the effectiveness of the proposed algorithm using simulation and experimental results

Hemoglobin to red cell distribution width ratio as a prognostic marker for ischemic stroke after mechanical thrombectomy

BackgroundThe hemoglobin to red cell distribution width ratio (HRR) has been experimentally associated with the prognosis of acute ischemic stroke (AIS). However, its relationship with mechanical thrombectomy (MT) for AIS remains unclear. Therefore, this study aimed to investigate the relationship between HRR at admission, follow-up HRR, and clinical outcomes in patients undergoing MT.MethodsAcute ischemic stroke patients undergoing MT were consecutively enrolled from January 2017 to December 2022. Demographic, clinical, and laboratory information were collected. HRR was measured by dividing hemoglobin (Hb) by red cell distribution width (RDW) at admission and after 24 h of MT. Clinical outcomes after 3 months were evaluated using the modified Rankin Scale (mRS). The primary outcome was poor prognosis (mRS > 2) at 3 months, while the secondary outcome was death within 3 months.ResultsA total of 310 patients were analyzed, of whom 216 patients (69.7%) had poor prognosis, and 92 patients (29.6%) died. Patients with a poor prognosis and death had significantly lower HRR levels at admission and after 24 h. HRR at admission was not associated with clinical outcomes according to multivariable logistic regression analysis. However, HRR after 24 h was significantly associated with poor prognosis (adjusted odds ratio [OR]: 0.646, 95% confidence interval [CI]: 0.520–0.803, p < 0.001) and death (adjusted OR: 0.615, 95% CI: 0.508–0.744, p < 0.001). Receiver-operating characteristic curve analysis demonstrated the predictive ability of HRR after 24 h, with areas under the curves of 0.790 for poor prognosis and 0.771 for death.ConclusionRapidly measurable HRR levels are an independent marker of outcome after MT in AIS patients. This may provide a reliable auxiliary outcome measure for clinical routine and interventional therapy

GWAS Identifies Novel Susceptibility Loci on 6p21.32 and 21q21.3 for Hepatocellular Carcinoma in Chronic Hepatitis B Virus Carriers

Genome-wide association studies (GWAS) have recently identified KIF1B as susceptibility locus for hepatitis B virus (HBV)–related hepatocellular carcinoma (HCC). To further identify novel susceptibility loci associated with HBV–related HCC and replicate the previously reported association, we performed a large three-stage GWAS in the Han Chinese population. 523,663 autosomal SNPs in 1,538 HBV–positive HCC patients and 1,465 chronic HBV carriers were genotyped for the discovery stage. Top candidate SNPs were genotyped in the initial validation samples of 2,112 HBV–positive HCC cases and 2,208 HBV carriers and then in the second validation samples of 1,021 cases and 1,491 HBV carriers. We discovered two novel associations at rs9272105 (HLA-DQA1/DRB1) on 6p21.32 (OR = 1.30, P = 1.13×$10^{−19}$) and rs455804 (GRIK1) on 21q21.3 (OR = 0.84, P = 1.86×$10^{−8}$), which were further replicated in the fourth independent sample of 1,298 cases and 1,026 controls (rs9272105: OR = 1.25, P = 1.71×$10^{−4}$; rs455804: OR = 0.84, P = 6.92×$10^{−3}$). We also revealed the associations of HLA-DRB1*0405 and 0901*0602, which could partially account for the association at rs9272105. The association at rs455804 implicates GRIK1 as a novel susceptibility gene for HBV–related HCC, suggesting the involvement of glutamate signaling in the development of HBV–related HCC

Experimental Research on Micro-Doppler Effect of Multi-rotor Drone with Digital Television Based Passive Radar

In this paper, experimental results of micro-Doppler effect on a multi-rotor drone with digital television based passive radar are discussed. First, the bistatic passive radar micro-motion model of the drone is established. Second, key techniques of micro-motion signal extraction are briefly described. Finally, the experimental process is introduced, including experimental scene configuration and analysis of typical experimental results of micro-Doppler effect. The experimental results agree with the theoretical analysis of the motion parameters of the drone, thereby confirming the technical feasibility of detecting the micro-Doppler effect of the multi-rotor drone using the digital television based passive radar

Adjuvant Treatment with Xiaoqinglong Formula for Bronchial Asthma in Acute Attack: A Systematic Review of Randomized Controlled Trials

Background. XQLF (Xiaoqinglong formula) is the most commonly used prescription of traditional Chinese medicine in the treatment of asthma. XQLF combined with western medicine has been used to treat bronchial asthma in more and more cases, and good results have been achieved. Therefore, this meta-analysis aimed to evaluate the adjuvant treatment of traditional Chinese medicine classic herbal formula XQLF with bronchial asthma in acute attack. Methods. The following electronic databases were systematically searched from inception to April 2019: PubMed, EMBASE database, Cochrane Library, China National Knowledge Infrastructure (CNKI), WanFang, VIP Database for Chinese Technical Periodicals, and China Biology Medicine (CBM). Two reviewers searched these databases and independently evaluated all the eligible articles for inclusion. Stata 14.0 was used for data synthesis and analysis. Results. A total of 33 RCTs (randomized controlled trials) including 2176 patients were enrolled. All of the patients in these studies were in the acute attack stage of asthma. We conducted subgroup analysis according to the duration of treatment, which was 14 days, 10 days, and 7 days, respectively. The overall results show that adjuvant treatment with XQLF significantly improve CER (clinical efficacy rate) (RR = 1.17; 95% CI, 1.14 to 1.21; P<0.0001) and promote pulmonary function including FEV1 (WMD = 0.35; 95% CI, 0.27 to 0.43; P<0.0001), PEF (SMD = 1.02; 95% CI, 0.49 to 1.55; P<0.0001), and FVC (WMD = 0.51; 95% CI, 0.35 to 0.66; P<0.0001). The adjuvant treatment of XQLF can also reduce serum IgE concentration (SMD = −1.39; 95% CI, 1.92 to −0.85; P<0.0001) and serum EOS concentration at 14 days (WMD = −39.85; 95% CI, −56.20 to −23.49; P<0.0001). Conclusion. This study finally showed that XQLF has the auxiliary effect of improving the efficiency, promoting the lung function, and reducing the serum IgE in the treatment of acute attack asthma. This trial is registered with CRD42019133549