Demolition, rehabilitation, and conservation: heritage in Shanghai’s urban regeneration, 1990–2015 [post-print]

Urban heritage sites in central cities are most difficult to protect during rapid and large scale urban (re)development. Rising land values from property development conflict with and constrain heritage preservation. Compared with many cities in developed and developing countries, large Chinese cities have experienced a stronger redevelopment imperative, faster population growth, and a weaker concern for urban heritages over the last three decades. We use Shanghai to examine the contested evolution of heritage preservation against massive urban redevelopment through three stages from 1990 to the present. Using three heritage projects (Xintiandi, Tianzifang, Bugaoli), we focus on: 1) how each project was implemented and the economic and spatial outcomes each has produced; 2) how the mode of each project’s development interacted with the shifting official policies for heritage preservation; and 3) the implications of the findings, theoretical and practical, for more effective urban preservation

Demolition, Rehabilitation, and Conservation: Heritage in Shanghai’s Urban Regeneration, 1990–2015 [post-print]

Urban heritage sites in central cities are most difficult to protect during rapid and large scale urban (re)development. Rising land values from property development conflict with and constrain heritage preservation. Compared with many cities in developed and developing countries, large Chinese cities have experienced a stronger redevelopment imperative, faster population growth, and a weaker concern for urban heritages over the last three decades. We use Shanghai to examine the contested evolution of heritage preservation against massive urban redevelopment through three stages from 1990 to the present. Using three heritage projects (Xintiandi, Tianzifang, Bugaoli), we focus on: 1) how each project was implemented and the economic and spatial outcomes each has produced; 2) how the mode of each project’s development interacted with the shifting official policies for heritage preservation; and 3) the implications of the findings, theoretical and practical, for more effective urban preservation

Existence of φ\varphi-attractor and estimate of their attractive velocity for infinite-dimensional dynamical systems

This paper is devoted to the quantitative study of the attractive velocity of generalized attractors for infinite-dimensional dynamical systems. We introduce the notion of~$\varphi$-attractor whose attractive speed is characterized by a general non-negative decay function~$\varphi$, and prove that~$\varphi$-decay with respect to noncompactness measure is a sufficient condition for a dissipitive system to have a~$\varphi$-attractor. Furthermore, several criteria for~$\varphi$-decay with respect to noncompactness measure are provided. Finally, as an application, we establish the existence of a generalized exponential attractor and the specific estimate of its attractive velocity for a semilinear wave equation with a critical nonlinearity.Comment: arXiv admin note: substantial text overlap with arXiv:2108.0741

Demolition, rehabilitation, and conservation: heritage in Shanghai’s urban regeneration, 1990–2015

Urban heritage sites in central cities are most difficult to protect during rapid and large scale urban (re)development. Rising land values from property development conflict with and constrain heritage preservation. Compared with many cities in developed and developing countries, large Chinese cities have experienced a stronger redevelopment imperative, faster population growth, and a weaker concern for urban heritages over the last three decades. We use Shanghai to examine the contested evolution of heritage preservation against massive urban redevelopment through three stages from 1990 to the present. Using three heritage projects (Xintiandi, Tianzifang, Bugaoli), we focus on: 1) how each project was implemented and the economic and spatial outcomes each has produced; 2) how the mode of each project’s development interacted with the shifting official policies for heritage preservation; and 3) the implications of the findings, theoretical and practical, for more effective urban preservation

Nitric Oxide Synthase in Male Urological and Andrologic Functions

Nitric oxide (NO), a crucial signaling molecule, is synthesized by the nitric oxide synthase (NOS) enzyme. The significant effects of NOS are under exploration, and the roles of potential therapy targets for diseases of NOS are widely accepted. In this chapter, we summarized the important roles of NOS mainly on pathogenesis of prostate diseases, male infertility, erectile dysfunction and, addition, the potential therapeutic efficacies of NOS for those diseases

The Regulatory Role of Long Noncoding RNAs in Different Brain Cell Types Involved in Ischemic Stroke

Stroke results in high morbidity and high mortality worldwide, with ischemic stroke accounting for 80% to 85%. As effective treatments for ischemic stroke remain limited because of the narrow therapeutic time window, a better understanding of the pathologic mechanism and new therapeutic intervention targets are needed. Due to the development of next-generation sequencing technologies and the genome-wide analysis of eukaryotic transcriptomes, a large amount of evidence to date demonstrates that long noncoding RNAs (lncRNAs) play a vital role in gene regulation and in ischemic stroke. In recent years, many studies have been focused on the clinical significance of lncRNAs in ischemic stroke, and data shows that the pathological processes underlying ischemic stroke are driven by interactions among different brain cell types, including neurons, glial cells, and vascular cells, which actively participate in the mechanisms of tissue injury and repair. In this mini review article, we provide an overview of the characteristics and underlying regulation mechanisms of lncRNAs relevant to different brain cell types during the course of ischemic stroke. Moreover, we reveal the roles of lncRNAs as potential biomarkers and treatment targets in ischemic stroke

The efficacy of the Hiline gas permeable contact lens for the management of Keratoconus

Purpose: To investigate the efficacy of the Hiline® gas permeable contact lens (Hiline® GP) for keratoconus in clinical practice in correcting visual acuity. Methods: 218 eyes of 126 patients with keratoconus were fitted with Hiline® lenses. The fit of the lenses was evaluated. Visual acuity measurements were taken with spectacle lenses and with the Hiline lenses. The period of follow-up to observe for complications ranged from 3 to 27 months. Results: In all eyes, the Hiline® GP provided acceptable vision. There was a statistically significant improvement in vision with the Hiline® GP compared with spectacle lenses (t=10.90, p<0.0001). Initial evaluation showed that 169 lenses (77.52%) demonstrated a three-pointtouch relationship with the cornea 38 lenses (17.43%) had an apical clearance relationship with the cornea and 11 lenses (5.05%) had an apical bearing relationship. No severe complications were observed. Conclusions: Using corneal topography as a guide, a high success rate was achieved with the Hiline® GP design. It is easy to reach the ideal fit and to improve the visual acuity. These indicate the usefulness of Hiline® lens in clinical practice

First report and multilocus genotyping of Enterocytozoon bieneusi from Tibetan pigs in southwestern China

Enterocytozoon bieneusi is a common intestinal pathogen in a variety of animals. While E. bieneusi genotypes have become better-known, there are few reports on its prevalence in the Tibetan pig. This study investigated the prevalence, genetic diversity, and zoonotic potential of E. bieneusi in the Tibetan pig in southwestern China. Tibetan pig feces (266 samples) were collected from three sites in the southwest of China. Feces were subjected to PCR amplification of the internal transcribed spacer (ITS) region. Enterocytozoon bieneusi was detected in 83 (31.2%) of Tibetan pigs from the three different sites, with 25.4% in Kangding, 56% in Yaan, and 26.7% in Qionglai. Prevalence varies according to age group, from 24.4% (age 0–1 years) to 44.4% (age 1–2 years). Four genotypes of E. bieneusi were identified: two known genotypes EbpC (n = 58), Henan-IV (n = 24) and two novel genotypes, SCT01 and SCT02 (one of each). We compare our results with a compilation of published results on the host range and geographical distribution of E. bieneusi genotypes in China. Phylogenetic analysis showed these four genotypes clustered to group 1 with zoonotic potential. Multilocus sequence typing (MLST) analysis of three microsatellites (MS1, MS3, MS7) and one minisatellite (MS4) was successful in 47, 48, 23 and 47 positive specimens and identified 10, 10, 5 and 5 genotypes at four loci, respectively. This study indicates the potential danger of E. bieneusi to Tibetan pigs in southwestern China, and offers basic advice for preventing and controlling infections