The Impact of Green Disclosure Nudging in Online Reuse Markets: Evidence from a Natural Experiment

As the environment continues to deteriorate, for managers, the means of shifting consumer behavior to green is urgently needed. Information disclosure as a tactic to promote green consumption has been widely studied, which typically stimulates demand for new green products through cost disclosure. In contrast, the impact of environmental benefit information disclosure on green consumption, especially on online reuse platforms, remains to be ascertained. In this study, we examine the economic effects of a green disclosure nudge through a natural experiment. Drawing on daily sales data, we find that the green disclosure nudge can stimulate consumer demand and generate economic benefits. We provide suggestive evidence that this positive effect stems from an increase in consumers’ perceptions of the functional and symbolic value of used products, respectively. In addition, exploratory analysis shows that the nudge may have potential social benefits. The findings provide practical and theoretical implications for promoting green consumption

Advances in Acute Myeloid Leukemia Stem Cells

As a common hematological malignant tumor, acute leukemia is believed to originate from a subpopulation of special cancer cells, named cancer stem cells. Cancer stem cells are recognized to be the main source of tumor origin, multidrug resistance, metastasis, and recurrence. Leukemic stem cells (LSCs) were first identified and confirmed to play an important role in the occurrence and development of leukemia. In this article, we summarize the following content: special markers and sorting methods for acute myeloid leukemia stem cells and the role of cancer stem cells in treatment resistance, metastasis and invasion, recurrence, and target treatment of acute leukemia

Application of a Split Luciferase Complementation Assay for theDetection of Viral Protein-Protein Interactions

Intraviral protein-protein interactions are critical for virus survival in the host. Discovery of such interactions is important to understand molecular mechanisms of viral replication and pathogenesis. The development of a cell-based assay that can be employed to examine systematically viral protein interactions is described. The method, known as the Split Luciferase Complementation Assay (SLCA), is based on the principle that N- and C-terminal domains of luciferase alone do not emit luminescence; however, if fused to interacting proteins the two nonfunctional halves can be brought into close enough proximity through a specific protein-protein interaction to restore the functions of the enzyme and emit detectable light. The well-studied influenza B polymerase acidic protein (PA) and basic protein 1 (PB1) interaction was used as a model system to develop the assay. Consistent with previous studies, a strong PA-PB1 interaction was demonstrated in the assay. The PA-PB1 interaction was also disrupted by single amino acid mutations in the N-terminal domain of PB1 that is responsible for binding PA. The described SLCA is highly specific and easy to perform, and thus may be useful for studying protein-protein interactions in viral diseases

Amorphous quaternary alloy nanoplates for efficient catalysis of hydrogen evolution reaction

Developing a highly efficient non-precious transition metal-based electrocatalyst via a facile approach toward the hydrogen evolution reaction (HER) is critical for large-scale hydrogen production but still remains challenging. Herein, a cost-effective electrochemical deposition strategy is rationally proposed to construct amorphous quaternary FeCoNiCu alloy nanosheets supported on nickel foam (NF) towards this challenge. Benefiting from the synergistic effect of multi-metal atoms interaction and the high exposure of active sites caused by abundant open voids, the as-synthesized FeCoNiCu/NF electrode exhibits high catalytic activity and robustness toward HER in alkaline solution, requiring an overpotential of only 35 mV to reach a current density of 10 mA cm–2. This study may pave a new avenue to design advanced electrocatalyst for energy conversion