9 research outputs found
Relationships Between D-Dimer Levels and Stroke Risk as Well as Adverse Clinical Outcomes After Acute Ischemic Stroke or Transient Ischemic Attack: A Systematic Review and Meta-Analysis
Objective: Abnormal elevation of D-dimer levels is an important indicator of
disseminated intravascular clotting. Therefore, we hypothesized that high D-dimer levels
were associated with the risk of stroke and adverse clinical outcomes of patients with
acute ischemic stroke (AIS) or transient ischemic attack (TIA).
Methods: The present meta-analysis aimed to systematically analyze the associations
between D-dimer and the risk of stroke as well as the clinical outcomes of patients with
post-stroke or TIA. Meanwhile, dose–response analyses were conducted when there
were sufficient data available. Three electronic databases including Pubmed, the Embase
database, and the Cochrane Library were searched by two investigators independently.
All the pooled results were expressed as risk ratios (RRs).
Results: Finally, 22 prospective cohort studies were included into this meta-analysis.
The results suggested that high D-dimer levels were associated with increased risks of
total stroke (RR 1.4, 95%CI 1.20–1.63), hemorrhagic stroke (RR 1.25, 95%CI 0.69–2.25),
and ischemic Stroke (RR 1.55, 95%CI 1.22–1.98), and the dose-dependent relationship
was not found upon dose–response analyses. Besides, the high D-dimer levels on
admission were correlated with increased risks of all-cause mortality [RR 1.77, 95%
confidence interval (CI) 1.26–2.49], 5-day recurrence (RR 2.28, 95%CI 1.32–3.95), and
poor functional outcomes (RR 2.01, 95%CI 1.71–2.36) in patients with AIS or TIA.
Conclusions: On the whole, high D-dimer levels may be associated with the risks of total
stroke and ischemic stroke, but not with hemorrhagic stroke. However, dose–response
analyses do not reveal distinct evidence for a dose-dependent association of D-dimer
levels with the risk of stroke. Besides, high D-dimer levels on admission may predict
adverse clinical outcomes, including all-cause mortality, 5-day recurrence, and 90-day
poor functional outcomes, of patients with AIS or TIA. More studies are warranted to
quantify the effect of D-dimer levels on the risk of stroke or TIA, so as to verify and
substantiate this conclusion in the future
Effect of solvent on Se-modified ruthenium/carbon catalyst for oxygen reduction
Se-modified ruthenium supporting on carbon (Sex–Ru/C) electrocatalyst was prepared by solvothermal one-step synthesis method. The reaction mechanism was revealed after discussing impact of different solvents (i-propanol and EG) in solvotermal reaction. The result showed that the grain size of Se-modified ruthenium electrocatalyst was as small as 1 to 3 nm and highly dispersed on carbon surface. X-ray photoelectron spectroscopy (XPS) presented that selenium mainly existed in the catalyst in the form of elemental selenium and selenium oxides when the solvent was EG and i-propanol, respectively. The oxygen reduction reaction (ORR) performance was improved by appearance of selenium oxides
Relationships Between D-Dimer Levels and Stroke Risk as Well as Adverse Clinical Outcomes After Acute Ischemic Stroke or Transient Ischemic Attack: A Systematic Review and Meta-Analysis
Objective: Abnormal elevation of D-dimer levels is an important indicator of
disseminated intravascular clotting. Therefore, we hypothesized that high D-dimer levels
were associated with the risk of stroke and adverse clinical outcomes of patients with
acute ischemic stroke (AIS) or transient ischemic attack (TIA).
Methods: The present meta-analysis aimed to systematically analyze the associations
between D-dimer and the risk of stroke as well as the clinical outcomes of patients with
post-stroke or TIA. Meanwhile, dose–response analyses were conducted when there
were sufficient data available. Three electronic databases including Pubmed, the Embase
database, and the Cochrane Library were searched by two investigators independently.
All the pooled results were expressed as risk ratios (RRs).
Results: Finally, 22 prospective cohort studies were included into this meta-analysis.
The results suggested that high D-dimer levels were associated with increased risks of
total stroke (RR 1.4, 95%CI 1.20–1.63), hemorrhagic stroke (RR 1.25, 95%CI 0.69–2.25),
and ischemic Stroke (RR 1.55, 95%CI 1.22–1.98), and the dose-dependent relationship
was not found upon dose–response analyses. Besides, the high D-dimer levels on
admission were correlated with increased risks of all-cause mortality [RR 1.77, 95%
confidence interval (CI) 1.26–2.49], 5-day recurrence (RR 2.28, 95%CI 1.32–3.95), and
poor functional outcomes (RR 2.01, 95%CI 1.71–2.36) in patients with AIS or TIA.
Conclusions: On the whole, high D-dimer levels may be associated with the risks of total
stroke and ischemic stroke, but not with hemorrhagic stroke. However, dose–response
analyses do not reveal distinct evidence for a dose-dependent association of D-dimer
levels with the risk of stroke. Besides, high D-dimer levels on admission may predict
adverse clinical outcomes, including all-cause mortality, 5-day recurrence, and 90-day
poor functional outcomes, of patients with AIS or TIA. More studies are warranted to
quantify the effect of D-dimer levels on the risk of stroke or TIA, so as to verify and
substantiate this conclusion in the future
Relationships Between D-Dimer Levels and Stroke Risk as Well as Adverse Clinical Outcomes After Acute Ischemic Stroke or Transient Ischemic Attack: A Systematic Review and Meta-Analysis
Objective: Abnormal elevation of D-dimer levels is an important indicator of
disseminated intravascular clotting. Therefore, we hypothesized that high D-dimer levels
were associated with the risk of stroke and adverse clinical outcomes of patients with
acute ischemic stroke (AIS) or transient ischemic attack (TIA).
Methods: The present meta-analysis aimed to systematically analyze the associations
between D-dimer and the risk of stroke as well as the clinical outcomes of patients with
post-stroke or TIA. Meanwhile, dose–response analyses were conducted when there
were sufficient data available. Three electronic databases including Pubmed, the Embase
database, and the Cochrane Library were searched by two investigators independently.
All the pooled results were expressed as risk ratios (RRs).
Results: Finally, 22 prospective cohort studies were included into this meta-analysis.
The results suggested that high D-dimer levels were associated with increased risks of
total stroke (RR 1.4, 95%CI 1.20–1.63), hemorrhagic stroke (RR 1.25, 95%CI 0.69–2.25),
and ischemic Stroke (RR 1.55, 95%CI 1.22–1.98), and the dose-dependent relationship
was not found upon dose–response analyses. Besides, the high D-dimer levels on
admission were correlated with increased risks of all-cause mortality [RR 1.77, 95%
confidence interval (CI) 1.26–2.49], 5-day recurrence (RR 2.28, 95%CI 1.32–3.95), and
poor functional outcomes (RR 2.01, 95%CI 1.71–2.36) in patients with AIS or TIA.
Conclusions: On the whole, high D-dimer levels may be associated with the risks of total
stroke and ischemic stroke, but not with hemorrhagic stroke. However, dose–response
analyses do not reveal distinct evidence for a dose-dependent association of D-dimer
levels with the risk of stroke. Besides, high D-dimer levels on admission may predict
adverse clinical outcomes, including all-cause mortality, 5-day recurrence, and 90-day
poor functional outcomes, of patients with AIS or TIA. More studies are warranted to
quantify the effect of D-dimer levels on the risk of stroke or TIA, so as to verify and
substantiate this conclusion in the future
Effect of Saline Soil Cracks on Satellite Spectral Inversion Electrical Conductivity
The dehydration cracking of saline soil is a kind of common natural phenomenon, and the cracks of saline soil will affect the satellite spectrum, and then affect the accuracy of satellite spectral inversion of electrical conductivity (EC). This study introduces the concept of crack rate (CR) to describe the crack information of saline soil, and quantifies the influence of saline soil crack on the EC of satellite spectral inversion. In 2014 and 2020, the satellite-ground synchronous observation experiments of soda-type inland saline soil and coastal chlorinated-type saline soil were carried out, and the CR of surface cracked saline soil was extracted by an image processing algorithm. For the saline soil spectrum data, the correlation analysis method is used to establish the best band combination that characterizes the relationship between the different saline soil spectrum data and salinity, and the EC inversion model is established using the BP neural network method. The results show that: after the CR is introduced, the determination coefficient (R2) for the EC of soda-type saline soil satellite spectral inversion increased from 0.59 to 0.67, with an increase of 14.42%, and the mean square error (MSE) reduced from 0.20 to 0.16, with a decrease of 19.49%. The R2 for the EC of coastal chlorinated-type saline soil satellite spectral inversion increased from 0.64 to 0.75, an increase of 17.73%, and the MSE decreased from 0.16 to 0.12, a decrease of 25.15%. The study proved the influence of the cracks in the saline soil on the satellite spectrum and provided a new way to improve the accuracy of the satellite spectrum inversion of the EC of the cracked saline soil