28 research outputs found
Dynamic analysis of a train-bridge system to vessel collision and running safety of high-speed trains
A dynamic analysis model is established for a train-bridge system subjected to a vessel collision-load. A (32+48+32) m continuous bridge with PC box girders and a CRH2 high-speed train are considered as a case study. The whole histories of the train running on the bridge are simulated while the vessel collision load acting on the pier, based on which the dynamic responses of the bridge and the running safety indices of the train on the bridge are evaluated. The results show that the dynamic responses of the bridge are greatly increased by the vessel collision load, resulting in a big influence on the running safety of high-speed train
Bridge damage identification from moving load induced deflection based on wavelet transform and Lipschitz exponent
The wavelet transform and Lipschitz exponent perform well in detecting signal singularity.With the bridge crack damage modeled as rotational springs based on fracture mechanics, the deflection time history of the beam under the moving load is determined with a numerical method. The
continuous wavelet transformation (CWT) is applied to the deflection of the beam to identify the location of the damage, and the Lipschitz exponent is used to evaluate the damage degree. The influence of different damage degrees,multiple damage, different sensor locations, load velocity and load magnitude are studied.Besides, the feasibility of this method is verified by a model experiment
Metformin Uniquely Prevents Thrombosis by Inhibiting Platelet Activation and mtDNA Release
Thrombosis and its complications are the leading cause of death in patients with diabetes. Metformin, a first-line therapy for type 2 diabetes, is the only drug demonstrated to reduce cardiovascular complications in diabetic patients. However, whether metformin can effectively prevent thrombosis and its potential mechanism of action is unknown. Here we show, metformin prevents both venous and arterial thrombosis with no significant prolonged bleeding time by inhibiting platelet activation and extracellular mitochondrial DNA (mtDNA) release. Specifically, metformin inhibits mitochondrial complex I and thereby protects mitochondrial function, reduces activated platelet-induced mitochondrial hyperpolarization, reactive oxygen species overload and associated membrane damage. In mitochondrial function assays designed to detect amounts of extracellular mtDNA, we found that metformin prevents mtDNA release. This study also demonstrated that mtDNA induces platelet activation through a DC-SIGN dependent pathway. Metformin exemplifies a promising new class of antiplatelet agents that are highly effective at inhibiting platelet activation by decreasing the release of free mtDNA, which induces platelet activation in a DC-SIGN-dependent manner. This study has established a novel therapeutic strategy and molecular target for thrombotic diseases, especially for thrombotic complications of diabetes mellitus
Traffic Capacity Assessment of the Urban Elevated Bridge after Near-Field Explosion Based on the Response Surface Method
The traffic capacity of the urban elevated bridge is assessed after it is attacked by a near-field explosion, using the residual bearing capacity of the damaged pier as the assessment index. First, the finite element model of a reinforced concrete slab under near-field explosion is established by ANSYS/LS-DYNA software and compared with the experimental results, which verifies the effectiveness of the ALE (arbitrary Lagrangian–Eulerian) algorithm and the accuracy of the mesh size and material properties. Then, an “explosive-air-pier” coupling analysis model is constructed using the finite element method, and the damage of the reinforced concrete pier under three types of car bombs is evaluated. Furthermore, a response surface model for the residual bearing capacity of the pier is utilized to calculate the failure probabilities of various damage levels of the pier under the three types of car bombs and to assess the traffic capacity of the bridge after near-field explosion. The established assessment method can be used to predict the probability of bridge structural damage at various levels under different types of car bombs and to provide a reference for exploring a probability-based safety assessment method of post-explosion bridges
Kinematic and Dynamic Vehicle Model-Assisted Global Positioning Method for Autonomous Vehicles with Low-Cost GPS/Camera/In-Vehicle Sensors
Real-time, precise and low-cost vehicular positioning systems associated with global continuous coordinates are needed for path planning and motion control in autonomous vehicles. However, existing positioning systems do not perform well in urban canyons, tunnels and indoor parking lots. To address this issue, this paper proposes a multi-sensor positioning system that combines a global positioning system (GPS), a camera and in-vehicle sensors assisted by kinematic and dynamic vehicle models. First, the system eliminates image blurring and removes false feature correspondences to ensure the local accuracy and stability of the visual simultaneous localisation and mapping (SLAM) algorithm. Next, the global GPS coordinates are transferred to a local coordinate system that is consistent with the visual SLAM process, and the GPS and visual SLAM tracks are calibrated with the improved weighted iterative closest point and least absolute deviation methods. Finally, an inverse coordinate system conversion is conducted to obtain the position in the global coordinate system. To improve the positioning accuracy, information from the in-vehicle sensors is fused with the interacting multiple-model extended Kalman filter based on kinematic and dynamic vehicle models. The developed algorithm was verified via intensive simulations and evaluated through experiments using KITTI benchmarks (A project of Karlsruhe Institute of Technology and Toyota Technological Institute at Chicago) and data captured using our autonomous vehicle platform. The results show that the proposed positioning system improves the accuracy and reliability of positioning in environments in which the Global Navigation Satellite System is not available. The developed system is suitable for the positioning and navigation of autonomous vehicles
Dynamic analysis of coupled train - ladder track - elevated bridge system
As a new type of vibration reduction, the ladder track system has been successfully used in engineering. In this paper, a numerical model of the train-track-viaduct system is established to study the dynamic responses of an elevated bridge with ladder track. The system is composed of a vehicle submodel, a track submodel and a bridge submodel, with the measured track irregularities as the system self-excitation. The whole time histories of a train running through an elevated bridge with 3Ă—27m continuous PC box girders are simulated. The dynamic responses of the bridge such as deflections, lateral and vertical accelerations, and the vehicle responses such as derailment factors, offload factors and car-body accelerations are calculated. The calculated results are partly validated through the comparison with the experimental data. Compared to the common slab track, adapting the ladder sleeper can effectively reduce the accelerations of the bridge girder, and also reduce the car-body accelerations and offload factors of the train vehiclestatus: publishe
Kinematic and Dynamic Vehicle Model-Assisted Global Positioning Method for Autonomous Vehicles with Low-Cost GPS/Camera/In-Vehicle Sensors
Topping Failure Analysis of Anti-Dip Bedding Rock Slopes Subjected to Crest Loads
Crest loads are often encountered in hydropower, highway, open-pit and other engineering rock slopes. Toppling failure is one of the most common deformation failure types of anti-dip bedding rock slopes. Analysis on such failure of anti-dip bedding rock slopes subjected to crest loads has an important influence on engineering practice. Based on the step-by-step analysis approach proposed by Goodman and Bray, a geo-mechanical model was developed, and the related analysis approach was proposed for the toppling failure of anti-dip bedding rock slopes subjected to crest loads. Using the transfer coefficient method, a formulation was derived for calculating the residual thrust of slope toe and the support force required to meet the requirements of the slope stability under crest loads, which provided a scientific reference to design and support for such slopes. Through slope examples, the influence of crest loads on the residual thrust and sliding ratio coefficient was investigated for cases of different block widths and slope cut angles. The results show that there exists a critical block width for such slope. The influence of crest loads on the residual thrust is non-negligible when the block thickness is smaller than the critical value. Moreover, the influence of crest loads on the slope stability increases with the slope cut angle and the sliding ratio coefficient of anti-dip bedding rock slopes increases with the crest loads. Finally, the theoretical solutions and numerical simulations using Universal Distinct Element Code (UDEC) were compared, in which the consistent results show the applicability of both approaches
Bridge Damage Identification from Moving Load Induced Deflection Based on Wavelet Transform and Lipschitz Exponent
Study on Dynamic Amplification Coefficient of U-Shaped Girder Based on Vehicle-Bridge Coupling Dynamics
In this paper, a vehicle-bridge coupling dynamic model is established considering the vertical wheel-rail tight contact and the lateral simplified wheel-rail creeping. Through the site test and the numerical calculation, the dynamic deflections and the stresses of the U-shaped girder in the Nanjing S6 Urban Rail Transit in China are obtained, and the effectiveness of the established numerical model is verified. By changing the vehicle types and speeds, the dynamic amplification coefficients (DAFs) of the vertical deflections and the biaxial stresses at the girder bottom including the key points at the plate and section intersections are calculated. The research shows that the distribution of the lateral stresses is more complex than that of the deflection and the longitudinal stresses. Based on the calculation results considering various vehicle types, it is suggested that the DAFs of the vertical deflections and the longitudinal stresses are taken as 1.30, and the DAF of the lateral stresses remains at 1.40 as stipulated by the code. The research of this paper is to provide a reference for the structural design and size optimization of the U-shaped girders for urban rail transit