9,420 research outputs found

    Deduction of the quantum numbers of low-lying states of 6-nucleon systems based on symmetry

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    The inherent nodal structures of the wavefunctions of 6-nucleon systems have been investigated. The existence of a group of six low-lying states dominated by L=0 has been deduced. The spatial symmetries of these six states are found to be mainly {4,2} and {2,2,2}.Comment: 8 pages, no figure

    The gut microbiota, bile acids and their correlation in primary sclerosing cholangitis associated with inflammatory bowel disease.

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    BACKGROUND: Patients with primary sclerosing cholangitis associated with inflammatory bowel disease (PSC-IBD) have a very high risk of developing colorectal neoplasia. Alterations in the gut microbiota and/or gut bile acids could account for the increase in this risk. However, no studies have yet investigated the net result of cholestasis and a potentially altered bile acid pool interacting with a dysbiotic gut flora in the inflamed colon of PSC-IBD. AIM: The aim of this study was to compare the gut microbiota and stool bile acid profiles, as well as and their correlation in patients with PSC-IBD and inflammatory bowel disease alone. METHODS: Thirty patients with extensive colitis (15 with concomitant primary sclerosing cholangitis) were prospectively recruited and fresh stool samples were collected. The microbiota composition in stool was profiled using bacterial 16S rRNA sequencing. Stool bile acids were assessed by high-performance liquid chromatography tandem mass spectrometry. RESULTS: The total stool bile acid pool was significantly reduced in PSC-IBD. Although no major differences were observed in the individual bile acid species in stool, their overall combination allowed a good separation between PSC-IBD and inflammatory bowel disease. Compared with inflammatory bowel disease alone, PSC-IBD patients demonstrated a different gut microbiota composition with enrichment in Ruminococcus and Fusobacterium genus compared with inflammatory bowel disease. At the operational taxonomic unit level major shifts were observed within the Firmicutes (73%) and Bacteroidetes phyla (17%). Specific microbiota-bile acid correlations were observed in PSC-IBD, where 12% of the operational taxonomic units strongly correlated with stool bile acids, compared with only 0.4% in non-PSC-IBD. CONCLUSIONS: Patients with PSC-IBD had distinct microbiota and microbiota-stool bile acid correlations as compared with inflammatory bowel disease. Whether these changes are associated with, or may predispose to, an increased risk of colorectal neoplasia needs to be further clarified.info:eu-repo/semantics/publishedVersio

    Damage Assessment of Two-Way RC Slab Subjected to Blast Load using Mode Approximation Approach

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    Significant research efforts have been invested on studying the response and damage of structures subjected to blast loads for better life and property protections. The single-degree-of-freedom (SDOF) approach has been widely adopted to simplify the structural response analysis for engineering design purpose. However, such an approach under certain circumstances oversimplifies the structural behavior and might not give reliable predictions of structural responses to blast loads. On the other hand, although detailed high fidelity finite element (FE) approach is able to give relatively accurate predictions of structural response, it is unfortunately not straightforward for application and very time-consuming, which impedes its application among engineers. Therefore, a method that can assure not only reliability but also efficiency is highly needed for design practice. In the present study, mode approximation method with Pressure–Impulse (P-I) diagrams is applied to analyze response and damage of RC slab due to blast load. Slab under analysis is assumed rigid-plastic and simply supported. Shear failure, bending failure and combined failure modes are considered based on different failure modes. Critical equations for structural shear and bending failures are derived respectively with appropriate failure criteria. P–I diagrams are then developed for quick damage assessments. The analytical results are verified by comparing with high fidelity numerical simulations. The reliability and efficiency of using this approach for design and analyzing RC slab response under blast loads are demonstrated

    DancingLines: An Analytical Scheme to Depict Cross-Platform Event Popularity

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    Nowadays, events usually burst and are propagated online through multiple modern media like social networks and search engines. There exists various research discussing the event dissemination trends on individual medium, while few studies focus on event popularity analysis from a cross-platform perspective. Challenges come from the vast diversity of events and media, limited access to aligned datasets across different media and a great deal of noise in the datasets. In this paper, we design DancingLines, an innovative scheme that captures and quantitatively analyzes event popularity between pairwise text media. It contains two models: TF-SW, a semantic-aware popularity quantification model, based on an integrated weight coefficient leveraging Word2Vec and TextRank; and wDTW-CD, a pairwise event popularity time series alignment model matching different event phases adapted from Dynamic Time Warping. We also propose three metrics to interpret event popularity trends between pairwise social platforms. Experimental results on eighteen real-world event datasets from an influential social network and a popular search engine validate the effectiveness and applicability of our scheme. DancingLines is demonstrated to possess broad application potentials for discovering the knowledge of various aspects related to events and different media
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