3,004 research outputs found

    Micromachined membrane particle filters

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    We report here several particle membrane filters (8 x 8 mm^2) with circular, hexagonal and rectangular through holes. By varying hole dimensions from 6 to 12 pm, opening factors from 4 to 45 % are achieved. In order to improve the filter robustness, a composite silicon nitride/Parylene membrane technology is developed. More importantly, fluid dynamic performance of the filters is also studied by both experiments and numerical simulations. It is found that the gaseous flow through the filters depends strongly on opening factors, and the measured pressure drops are much lower than that from numerical simulation using the Navier-Stokes equation. Interestingly, surface velocity slip can only account for a minor part of the discrepancy. This suggests that a very interesting topic for micro fluid mechanics research is identified

    Nonlinear Near-Field Microwave Microscope For RF Defect Localization in Superconductors

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    Niobium-based Superconducting Radio Frequency (SRF) cavity performance is sensitive to localized defects that give rise to quenches at high accelerating gradients. In order to identify these material defects on bulk Nb surfaces at their operating frequency and temperature, it is important to develop a new kind of wide bandwidth microwave microscopy with localized and strong RF magnetic fields. By taking advantage of write head technology widely used in the magnetic recording industry, one can obtain ~200 mT RF magnetic fields, which is on the order of the thermodynamic critical field of Nb, on submicron length scales on the surface of the superconductor. We have successfully induced the nonlinear Meissner effect via this magnetic write head probe on a variety of superconductors. This design should have a high spatial resolution and is a promising candidate to find localized defects on bulk Nb surfaces and thin film coatings of interest for accelerator applications.Comment: 4 pages, 6 figures Journal-ref: 2010 Applied Superconductivity Conferenc

    Mgb2 Nonlinear Properties Investigated under Localized High RF Magnetic Field Excitation

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    In order to increase the accelerating gradient of Superconducting Radio Frequency (SRF) cavities, Magnesium Diboride (MgB2) opens up hope because of its high transition temperature and potential for low surface resistance in the high RF field regime. However, due to the presence of the small superconducting gap in the {\pi} band, the nonlinear response of MgB2 is potentially quite large compared to a single gap s-wave superconductor (SC) such as Nb. Understanding the mechanisms of nonlinearity coming from the two-band structure of MgB2, as well as extrinsic sources, is an urgent requirement. A localized and strong RF magnetic field, created by a magnetic write head, is integrated into our nonlinear-Meissner-effect scanning microwave microscope [1]. MgB2 films with thickness 50 nm, fabricated by a hybrid physical-chemical vapor deposition technique on dielectric substrates, are measured at a fixed location and show a strongly temperature-dependent third harmonic response. We propose that at least two mechanisms are responsible for this nonlinear response, one of which involves vortex nucleation and penetration into the film. [1] T. M. Tai, X. X. Xi, C. G. Zhuang, D. I. Mircea, S. M. Anlage, "Nonlinear Near-Field Microwave Microscope for RF Defect Localization in Superconductors", IEEE Trans. Appl. Supercond. 21, 2615 (2011).Comment: 6 pages, 6 figure

    Hyperphosphorylated tau in patients with refractory epilepsy correlates with cognitive decline: a study of temporal lobe resections

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    Temporal lobe epilepsy, the most prevalent form of chronic focal epilepsy, is associated with a high prevalence of cognitive impairment but the responsible underlying pathological mechanisms are unknown. Tau, the microtubule-associated protein, is a hallmark of several neurodegenerative diseases including Alzheimer’s disease and chronic traumatic encephalopathy. We hypothesized that hyperphosphorylated tau pathology is associated with cognitive decline in temporal lobe epilepsy and explored this through clinico-pathological study. We first performed pathological examination on tissue from 33 patients who had undergone temporal lobe resection between ages 50 and 65 years to treat drug-refractory temporal lobe epilepsy. We identified hyperphosphorylated tau protein using AT8 immunohistochemistry and compared this distribution to Braak patterns of Alzheimer’s disease and patterns of chronic traumatic encephalopathy. We quantified tau pathology using a modified tau score created specifically for analysis of temporal lobectomy tissue and the Braak staging, which was limited without extra-temporal brain areas available. Next, we correlated tau pathology with pre- and postoperative cognitive test scores and clinical risk factors including age at time of surgery, duration of epilepsy, history of secondary generalized seizures, history of head injury, handedness and side of surgery. Thirty-one of 33 cases (94%) showed hyperphosphorylated tau pathology in the form of neuropil threads and neurofibrillary tangles and pre-tangles. Braak stage analysis showed 12% of our epilepsy cohort had a Braak staging III-IV compared to an age-matched non-epilepsy control group from the literature (8%). We identified a mixture of tau pathology patterns characteristic of Alzheimer’s disease and chronic traumatic encephalopathy. We also found unusual patterns of subpial tau deposition, sparing of the hippocampus and co-localization with mossy fibre sprouting, a feature of temporal lobe epilepsy. We demonstrated that the more extensive the tau pathology, the greater the decline in verbal learning (Spearman correlation, r = −0.63), recall (r = −0.44) and graded naming test scores (r = −0.50) over 1-year post-temporal lobe resection (P < 0.05). This relationship with tau burden was also present when examining decline in verbal learning from 3 months to 1 year post-resection (r = −0.54). We found an association between modified tau score and history of secondary generalized seizures (likelihood-ratio χ2, P < 0.05) however there was no clear relationship between tau pathology and other clinical risk factors assessed. Our findings suggest an epilepsy-related tauopathy in temporal lobe epilepsy, which contributes to accelerated cognitive decline and has diagnostic and treatment implications

    The final publication is available at link.springer.com. An Optimal Control Approach to Find Sparse Data for Laplace Interpolation

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    Abstract. Finding optimal data for inpainting is a key problem in the context of partial differential equation-based image compression. We present a new model for optimising the data used for the reconstruction by the underlying homogeneous diffusion process. Our approach is based on an optimal control framework with a strictly convex cost functional containing an L1 term to enforce sparsity of the data and non-convex constraints. We propose a numerical approach that solves a series of convex optimisation problems with linear constraints. Our numerical examples show that it outperforms existing methods with respect to quality and computation time

    Plasma Membrane Intrinsic Proteins of Beta vulgaris L

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    Efficient magneto-optical trapping of Yb atoms with a violet laser diode

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    We report the first efficient trapping of rare-earth Yb atoms with a high-power violet laser diode (LD). An injection-locked violet LD with a 25 mW frequency-stabilized output was used for the magneto-optical trapping (MOT) of fermionic as well as bosonic Yb isotopes. A typical number of 4×1064\times 10^6 atoms for 174^{174}Yb with a trap density of ∌1×108/\sim 1\times10^8/cm3^3 was obtained. A 10 mW violet external-cavity LD (ECLD) was used for the one-dimensional (1D) slowing of an effusive Yb atomic beam without a Zeeman slower resulting in a 35-fold increase in the number of trapped atoms. The overall characteristics of our compact violet MOT, e.g., the loss time of 1 s, the loading time of 400 ms, and the cloud temperature of 0.7 mK, are comparable to those in previously reported violet Yb MOTs, yet with a greatly reduced cost and complexity of the experiment.Comment: 5 pages, 3 figures, 1 table, Phys. Rev. A (to be published

    Threshold J/ψ−J/\psi- production in nucleon-nucleon collisions

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    We analyze J/ψ−J/\psi- production in nucleon-nucleon collisions near threshold in the framework of a general model independent formalism, which can be applied to any reaction N+N→N+N+V0N+N\to N+N+V^0, where V0=ωV^0=\omega, ϕ\phi, or J/ψJ/\psi. Such reactions show large isotopic effects: a large difference for pppp- and pnpn-collisions, which is due to the different spin structure of the corresponding matrix elements. The analysis of the spin structure and of the polarization observables is based on symmetry properties of the strong interaction. Using existing experimental data on the different decays of J/ψ−J/\psi-meson, we suggest a model for N+N→N+N+J/ψN+N\to N+N+J/\psi, based on t−t-channel η+π\eta+\pi-exchanges. We predict polarization phenomena for the n+p→n+p+J/ψn+p\to n+p+J/\psi-reaction and the ratio of cross sections for npnp and pppp-collisions. For the processes η(π)+N→N+J/ψ\eta(\pi)+N\to N+J/\psi we apply two different approaches: vector meson exchange and local four-particle interaction. In both cases we find larger J/ψJ/\psi-production in npnp-collisions, with respect to pppp-collisions.Comment: 17 pages, 6 figure

    Symbiotic Bright Solitary Wave Solutions of Coupled Nonlinear Schrodinger Equations

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    Conventionally, bright solitary wave solutions can be obtained in self-focusing nonlinear Schrodinger equations with attractive self-interaction. However, when self-interaction becomes repulsive, it seems impossible to have bright solitary wave solution. Here we show that there exists symbiotic bright solitary wave solution of coupled nonlinear Schrodinger equations with repulsive self-interaction but strongly attractive interspecies interaction. For such coupled nonlinear Schrodinger equations in two and three dimensional domains, we prove the existence of least energy solutions and study the location and configuration of symbiotic bright solitons. We use Nehari's manifold to construct least energy solutions and derive their asymptotic behaviors by some techniques of singular perturbation problems.Comment: to appear in Nonlinearit

    Hierarchically heterostructured metal hydr(oxy)oxides for efficient overall water splitting

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    The design of highly efficient electrocatalysts containing non-precious metals is crucial for promoting overall water splitting in alkaline media. In particular, Janus catalysts simultaneously facilitating the hydrogen evolution reaction (HER) and oxygen evolution reaction (OER) are desirable. Herein, we fabricated a unique hierarchical heterostructure via growing Ni4W6O21(OH)2·4H2O (denoted as Ni-W-O) nanosheets on NiMoO4 rods, which was indispensable for regulating the morphology of the Ni-W-O structure. This heterostructure of Ni-W-O/NiMoO4 could be utilized as an electrocatalyst to realize superior activity for overall water splitting in 1.0 M KOH. It substantially promoted overall water splitting with 1.6 V at 30 mA cm-2, outperforming numerous bifunctional electrocatalysts under the same conditions. Notably, the remarkable stability for continuously splitting water endowed this hierarchical heterostructure with potential applications on a large scale. This work emphasizes the effectively controlled growth of heterostructured non-noble-metal catalysts for energy-conversion reaction
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