Astronomical optical frequency comb generation and test in a fiber-fed MUSE spectrograph

We here report on recent progress on astronomical optical frequency comb generation at innoFSPEC-Potsdam and present preliminary test results using the fiber-fed Multi Unit Spectroscopic Explorer (MUSE) spectrograph. The frequency comb is generated by propagating two free-running lasers at 1554.3 and 1558.9 nm through two dispersionoptimized nonlinear fibers. The generated comb is centered at 1590 nm and comprises more than one hundred lines with an optical-signal-to-noise ratio larger than 30 dB. A nonlinear crystal is used to frequency double the whole comb spectrum, which is efficiently converted into the 800 nm spectral band. We evaluate first the wavelength stability using an optical spectrum analyzer with 0.02 nm resolution and wavelength grid of 0.01 nm. After confirming the stability within 0.01 nm, we compare the spectra of the astro-comb and the Ne and Hg calibration lamps: the astro-comb exhibits a much larger number of lines than lamp calibration sources. A series of preliminary tests using a fiber-fed MUSE spectrograph are subsequently carried out with the main goal of assessing the equidistancy of the comb lines. Using a P3d data reduction software we determine the centroid and the width of each comb line (for each of the 400 fibers feeding the spectrograph): equidistancy is confirmed with an absolute accuracy of 0.4 pm

Determination of exciton reduced mass and gyromagnetic factor of wurtzite (inga)as nanowires by photoluminescence spectroscopy under high magnetic fields

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Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches

Extracellular vesicles (EVs), through their complex cargo, can reflect the state of their cell of origin and change the functions and phenotypes of other cells. These features indicate strong biomarker and therapeutic potential and have generated broad interest, as evidenced by the steady year-on-year increase in the numbers of scientific publications about EVs. Important advances have been made in EV metrology and in understanding and applying EV biology. However, hurdles remain to realising the potential of EVs in domains ranging from basic biology to clinical applications due to challenges in EV nomenclature, separation from non-vesicular extracellular particles, characterisation and functional studies. To address the challenges and opportunities in this rapidly evolving field, the International Society for Extracellular Vesicles (ISEV) updates its ‘Minimal Information for Studies of Extracellular Vesicles’, which was first published in 2014 and then in 2018 as MISEV2014 and MISEV2018, respectively. The goal of the current document, MISEV2023, is to provide researchers with an updated snapshot of available approaches and their advantages and limitations for production, separation and characterisation of EVs from multiple sources, including cell culture, body fluids and solid tissues. In addition to presenting the latest state of the art in basic principles of EV research, this document also covers advanced techniques and approaches that are currently expanding the boundaries of the field. MISEV2023 also includes new sections on EV release and uptake and a brief discussion of in vivo approaches to study EVs. Compiling feedback from ISEV expert task forces and more than 1000 researchers, this document conveys the current state of EV research to facilitate robust scientific discoveries and move the field forward even more rapidly