18 research outputs found

    On the Origin of Cosmic Magnetic Fields

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    We review the literature concerning how the cosmic magnetic fields pervading nearly all galaxies actually got started. some observational evidence involves the chemical abundance of the light elements Be and B, while another one is based on strong magnetic fields seen in high red shift galaxies. Seed fields, whose strength is of order 10^{-20} gauss, easily sprung up in the era preceding galaxy formation. Several mechanisms are proposed to amplify these seed fields to microgauss strengths. The standard mechanism is the Alpha-Omega dynamo theory. It has a major difficulty that makes unlikely to provide the sole origin. The difficulty is rooted in the fact that the total flux is constant. This implies that flux must be removed from the galactic discs. This requires that the field and flux be separated, for otherwise interstellar mass must be removed from the deep galactic gravitational and then their strength increased by the alpha omega theory.Comment: 90 pages and 6 figures; accepted for publication in Reports of Progress in Physics as an invited revie

    Worldwide trends in population-based survival for children, adolescents, and young adults diagnosed with leukaemia, by subtype, during 2000–14 (CONCORD-3) : analysis of individual data from 258 cancer registries in 61 countries

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    Background Leukaemias comprise a heterogenous group of haematological malignancies. In CONCORD-3, we analysed data for children (aged 0–14 years) and adults (aged 15–99 years) diagnosed with a haematological malignancy during 2000–14 in 61 countries. Here, we aimed to examine worldwide trends in survival from leukaemia, by age and morphology, in young patients (aged 0–24 years). Methods We analysed data from 258 population-based cancer registries in 61 countries participating in CONCORD-3 that submitted data on patients diagnosed with leukaemia. We grouped patients by age as children (0–14 years), adolescents (15–19 years), and young adults (20–24 years). We categorised leukaemia subtypes according to the International Classification of Childhood Cancer (ICCC-3), updated with International Classification of Diseases for Oncology, third edition (ICD-O-3) codes. We estimated 5-year net survival by age and morphology, with 95% CIs, using the non-parametric Pohar-Perme estimator. To control for background mortality, we used life tables by country or region, single year of age, single calendar year and sex, and, where possible, by race or ethnicity. All-age survival estimates were standardised to the marginal distribution of young people with leukaemia included in the analysis. Findings 164563 young people were included in this analysis: 121328 (73·7%) children, 22963 (14·0%) adolescents, and 20272 (12·3%) young adults. In 2010–14, the most common subtypes were lymphoid leukaemia (28205 [68·2%] patients) and acute myeloid leukaemia (7863 [19·0%] patients). Age-standardised 5-year net survival in children, adolescents, and young adults for all leukaemias combined during 2010–14 varied widely, ranging from 46% in Mexico to more than 85% in Canada, Cyprus, Belgium, Denmark, Finland, and Australia. Individuals with lymphoid leukaemia had better age-standardised survival (from 43% in Ecuador to ≄80% in parts of Europe, North America, Oceania, and Asia) than those with acute myeloid leukaemia (from 32% in Peru to ≄70% in most high-income countries in Europe, North America, and Oceania). Throughout 2000–14, survival from all leukaemias combined remained consistently higher for children than adolescents and young adults, and minimal improvement was seen for adolescents and young adults in most countries. Interpretation This study offers the first worldwide picture of population-based survival from leukaemia in children, adolescents, and young adults. Adolescents and young adults diagnosed with leukaemia continue to have lower survival than children. Trends in survival from leukaemia for adolescents and young adults are important indicators of the quality of cancer management in this age group.peer-reviewe

    The Reorientation in British Strategic Policy During the 1960s

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    In the period 1964 – 70 arguably the most significant decisions were taken in British strategic military policy in the whole post-war period. During these years, Britain narrowed its strategic focus away from a global orientation and towards a concentration upon the continent of Europe. With the aid of hindsight, such a transition appears to have been inevitable as Britain came to terms with its status as a middle-ranking European power. However, as the new Labour government came into office ..

    Dynamiques européennes. Nouvel espace, nouveaux acteurs

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    Les Ă©checs de la construction europĂ©enne font plus de bruit que ses succĂšs. Les blocages de l’Europe sont patents et, pourtant, l’Europe avance encore, car elle s’appuie depuis le milieu du XXe siĂšcle sur une « dynamique » ou un ensemble de « dynamiques » intĂ©ressantes Ă  analyser dans leur complexitĂ©. Les chercheurs qui ont contribuĂ© au prĂ©sent ouvrage ont concentrĂ© leur rĂ©flexion sur cette notion de « dynamique europĂ©enne » en scrutant une pĂ©riode dĂ©cisive, celle des annĂ©es soixante-dix et du dĂ©but des annĂ©es quatre-vingt. Avec l’élargissement de la CommunautĂ© europĂ©enne, de nouveaux acteurs entrent en scĂšne, un nouvel espace se dessine, de nouveaux enjeux s’imposent. Une identitĂ© nouvelle est mĂȘme affirmĂ©e Ă  la confĂ©rence de Copenhague en 1973, une identitĂ© politique communautaire, diffĂ©rente de la vieille et classique identitĂ© culturelle europĂ©enne. En outre, avec la « dĂ©tente » entre l’Est et l’Ouest et le processus d’Helsinki, l’Autre Europe, celle de l’autre cĂŽtĂ© du rideau de fer, est dĂšs cette Ă©poque concernĂ©e par la dynamique d’échanges intra-europĂ©ens. L’étude de ces changements dĂ©terminants, qui ont contribuĂ© Ă  modeler l’Europe d’aujourd’hui, a Ă©tĂ© dĂ©veloppĂ©e lors d’un colloque organisĂ© Ă  Oxford, sous la direction d’Élisabeth du RĂ©au (École doctorale « Espace europĂ©en contemporain », Paris III), d’Anne Deighton (St Anthony College, Oxford) et de Robert Frank (Institut Pierre Renouvin, Paris I), dans le cadre du vaste rĂ©seau international d’historiens travaillant sur « Les identitĂ©s europĂ©ennes au XXe siĂšcle »
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