Vigs invisier: ’n teologies-etiese besínning

In this article the characteristics of Aids are touched upon and then the (rather difficult) question whether Aids should be seen as God’s judgement over the sin (immorality) of man is discussed. Some typical aspects (sexual, medical, political and personal) are discussed and furthermore the line of argumentation is continued by elaborating on the calling of the church, the task of authorities and society as well as the responsibility of the family and the individual. The conclusion arrived at is that however serious the case of Aids may be, there is no room for pessimism, because Christians expect and await the full realisation of the kingdom of God This expectation does not nullify but maximises man’s responsibilty to fight Aids with all moral means at his disposal

Effect of specimen block orientation on separation artefact in pulpal sections

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Response op lesing van prof.Wentzel Van Huyssteen

Dit is nie ’n maklike taak om op hierdie prikkelende artikel van prof. Van Huyssteen (VH) te reageer nie. Dieskrywer se gedagtes neem somssulke hoë vlugte dat ek nie altyd seker is of ek horn, ook na herlesing, korrek verstaan nie. Ek gaan ’n paar temas op grond en sells na aanleiding van die voordrag uitlig en kortliks bespreek. Kritiek en waardering word nie altyd eksplisiel verwoord nie maar kom dikwels verskuil ter sprake

Die politieke dimensie in die romankuns van André P. Brink: 'n Etiese evaluering

The author justifies writing about the political dimension in the novels of André P. Brink on the basis that committed literature also embraces the political dimension as one of its m any dimensions. He thus proposes to deal not with whether but how this dimension manifests its e lf in the literature. A rising line of political involvement is detected in the late st novels - and this tendency can be defined in terms of "in situation alized violence ". An analysis of a number of novels, including Kennis van die aand, Houd-den-bek and Muur van die Pes underscores his views, and reveals, too, a view that the church is caught up in pietistic immobility, and that the novels abound in Existentia list, Marxist and even at times Calvin is ethical motifs. The political dimension is then evaluated in terms of Calvin is views and the Calvin is tradition - especially in view of the concept of the justifiability of violence and in surreciton

Liberate konserwatisme? H.G. Stoker en die ideologie van apartheid: 'n Verkenning

In this article the intriguing question is discussed how it could be possible that a Christian philosopher o f the stature of H. G. Stoker could legitimise a policy of apartheid. It is argued that each ideology has a blinding effect on its supporters; thus making it almost impossible to take a critical stance towards it. It has been attempted to explain in more detail that some key features of the Biblical message were overlooked and tinder-developed in the philosophy of Stoker

Verantwoordelikheid: 'n Etniese benadering*

The author deals with the concept of responsibility (“verantwoordelikheid”). He breaks the word up into component parts and then deals with each of these separately and ultimately in conjunction. These can be roughly summed up in terms of man being the questioned being (the questions being set by God). Man has to ‘respond’, being a ‘homo respondens’, and this response has to be done in love and in faith. Man also has to act in a manner that is responsive to the demands made: that is, to be involved in and with other people and issues. Man has to justify his actions, his life

Christian pedagogy, education and teaching

The question which confronts one at the outset is: What is the nature and content of that Christian pedagogy, education, teaching and type of school for which Calvinists in South Africa have struggled in the past, and in fact are still struggling for, even today

“Was sollen wir tun?” Theological reflections on aspects of the ethics of Karl Barth

The author investigates some aspects of the ethics of the wellknown Swiss theologian Karl Barth. The article focuses on to the coherence between dogmatics and ethics, aspects of theocentricity and christocentricty, followed by an exploration of Barth’s views on (homo-)sexuality and politics. Before concluding, a final question is discussed: did Barth practice what he preached? – that is the question regarding integrity. Although the author may not agree with some facets of Barth’s theology, he has and shows appreciation for many of Barth’s views on ethics

Neutron activation and high resolution gamma spectrometry - activation analysis

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The relationship between tumour budding, the tumour microenvironment and survival in patients with primary operable colorectal cancer

Background: Tumour budding has been reported to reflect invasiveness, metastasis and unfavourable prognosis in colorectal cancer. The aim of the study was to examine the relationship between tumour budding and clinicopathological characteristics, tumour microenvironment and survival in patients with primary operable colorectal cancer. Methods: A total of 303 patients from a prospective data set of patients with primary operable colorectal cancer were included in the study. The presence of budding was determined through assessment of all tumour-containing H&E slides and the number of tumour buds was counted using a 10 high-powered field method. Routine pathologic sections were used to assess: tumour necrosis, the tumour inflammatory cell infiltrate using Klintrup–Makinen (KM) grade and tumour stroma percentage (TSP) combined as the Glasgow Microenvironment Score (GMS). Results: High-grade tumour budding was present in 39% of all tumours and in 28% of node-negative tumours respectively. High-grade budding was significantly associated with T stage (P<0.001), N stage (P<0.001), TNM stage (P<0.001), serosal involvement (P<0.001), venous invasion (P<0.005), KM grade (P=0.022), high tumour stroma (P<0.001) and GMS (P<0.001). Tumour budding was associated with reduced cancer-specific survival (CSS) (HR=4.03; 95% confidence interval (CI), 2.50–6.52; P<0.001), independent of age (HR=1.47; 95% CI, 1.13–1.90; P=0.004), TNM stage (HR=1.52; 95% CI, 1.02–2.25; P=0.040), venous invasion (HR=1.73; 95% CI, 1.13–2.64; P=0.012) and GMS (HR=1.54; 95% CI, 1.15–2.07; P=0.004). Conclusions: The presence of tumour budding was associated with elements of the tumour microenvironment and was an independent adverse prognostic factor in patients with primary operable colorectal cancer. Specifically high tumour budding stratifies effectively the prognostic value of tumour stage, venous invasion and GMS. Taken together, tumour budding should be assessed routinely in patients with primary operable colorectal cancer