A flood forecasting neural network model with genetic algorithm

Author name used in this publication: K. W. Chau2006-2007 > Academic research: refereed > Publication in refereed journalAccepted ManuscriptPublishe

Data-driven models for monthly streamflow time series prediction

Author name used in this publication: K.W. Chau2010-2011 > Academic research: refereed > Publication in refereed journalAccepted ManuscriptPublishe

Rainfall–runoff modeling using artificial neural network coupled with singular spectrum analysis

Author name used in this publication: K. W. Chau2011-2012 > Academic research: refereed > Publication in refereed journalAccepted ManuscriptPublishe

Mathematical model of water quality rehabilitation with rainwater utilization : a case study at Haigang

Author name used in this publication: K. W. Chau2006-2007 > Academic research: refereed > Publication in refereed journalAccepted ManuscriptPublishe

Antiviral treatment for chronic hepatitis B

An updated review of the antiviral agents currently available or under trial for the treatment of chronic hepatitis B is presented. There are two broad groups: (1) immunomodulators including interferon α (which also has a direct antiviral effect), thymosin α1 and Theradigm-HBV and (2) viral suppressors such as famciclovir and lamivudine. These agents are still in clinical trial worldwide, singly or in combination. Their long term efficacy in the treatment of hepatitis B remains to be evaluated.published_or_final_versio

Evaluation of several algorithms in forecasting flood

Series: Lecture notes in computer scienceAuthor name used in this publication: K.W. Chau2005-2006 > Academic research: refereed > Publication in refereed journalAccepted ManuscriptPublishe

Non-invasive acquisition of fetal ECG from the maternal xyphoid process: a feasibility study in pregnant sheep and a call for open data sets

Objective: The utility of fetal heart rate (FHR) monitoring can only be achieved with an acquisition sampling rate that preserves the underlying physiological information on the millisecond time scale (1000 Hz rather than 4 Hz). For such acquisition, fetal ECG (fECG) is required, rather than the ultrasound to derive FHR. We tested one recently developed algorithm, SAVER, and two widely applied algorithms to extract fECG from a single channel maternal ECG signal recorded over the xyphoid process rather than the routine abdominal signal. Approach: At 126dG, ECG was attached to near-term ewe and fetal shoulders, manubrium and xyphoid processes (n=12). FECG served as the ground-truth to which the fetal ECG signal extracted from the simultaneously-acquired maternal ECG was compared. All fetuses were in good health during surgery (pH 7.29+/-0.03, pO2 33.2+/-8.4, pCO2 56.0+/-7.8, O2Sat 78.3+/-7.6, lactate 2.8+/-0.6, BE -0.3+/-2.4). Main result: In all animals, single lead fECG extraction algorithm could not extract fECG from the maternal ECG signal over the xyphoid process with the F1 less than 50%. Significance: The applied fECG extraction algorithms might be unsuitable for the maternal ECG signal over the xyphoid process, or the latter does not contain strong enough fECG signal, although the lead is near the mother's abdomen. Fetal sheep model is widely used to mimic various fetal conditions, yet ECG recordings in a public data set form are not available to test the predictive ability of fECG and FHR. We are making this data set openly available to other researchers to foster non-invasive fECG acquisition in this animal model

Comparison of several flood forecasting models in Yangtze River

Author name used in this publication: K. W. Chau2005-2006 > Academic research: refereed > Publication in refereed journalAccepted ManuscriptPublishe

The natural history of chronic hepatitis B infection

Chronic hepatitis B infection is a global health problem that affects about 300 million people. Of these, 75% are Chinese. Most Chinese who become chronic carriers, contract the virus during the perinatal period. The natural history of these chronic hepatitis B carriers includes an initial immune tolerance phase, followed by immune clearance and an inactive hepatitis B non-replicative phase with the development of cirrhosis that may be complicated by hepatocellular carcinoma. The classification of hepato-cellular carcinoma has recently been revised. Based on immunohistochemical studies, it has been found that patients with hepatocellular carcinoma and biliary markers have a poorer survival than patients with hepatocellular carcinoma but who have negative biliary markers. Sometimes, a fourth phase, a hepatitis B envelope-negative hepatitis B virus replicative phase, reflecting the emergence of a pre-core mutant strain, may follow. Our improved understanding of the natural history of chronic hepatitis B infection has led to more effective approaches towards the control of this viral infection and its sequelae. Most importantly, immunisation against hepatitis B virus in the perinatal setting has been shown to prevent chronic infection.published_or_final_versio

Modelling coupled water and heat transport in a soil–mulch–plant–atmosphere continuum (SMPAC) system

Author name used in this publication: K. W. Chau2006-2007 > Academic research: refereed > Publication in refereed journalAccepted ManuscriptPublishe