2,241 research outputs found

    Map the distribution of glaciofluvial deposits and associated glacial landforms

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    There are no author-identified significant results in this report

    Basic questions in the task of inheritance law reform

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    Changing family studie

    Develop a land use-peak runoff classification system for highway engineering purposes

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    The author has identified the following significant results. Based on the detail study of the Sunkhaze Stream Watershed, it is believed that good detailed drainage studies can be derived from repetitive ERTS imagery. Land use maps tailored to hydrologic study can be prepared from ERTS imagery. Significant changes in the Sunkhaze Stream and Otter Stream Watersheds at spring flood conditions have given important information on the causes for flooding in the town of Bradley

    Multidisciplinary analysis for highway engineering purposes

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    There are no author-identified significant results in this report

    A brief introduction to the use of event-related potentials in studies of perception and attention

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    Scintillation observations at Ancon and Jicamarca Observatories

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    Satellite scintillation and diffraction pattern scale size distribution from ionospheric irregularitie

    Serum vitamin D decreases during chemotherapy: an Australian prospective cohort study

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    Background and Objectives: Vitamin D plays an important role in bone and muscle function, and cell prolifera-tion. The impact of chemotherapy and associated behavioural changes such as fatigue and sun avoidance on vit-amin D (25(OH) D) is unknown. This study aims to evaluate variations in serum vitamin D during chemotherapy and the predictive value of latitude, season and pre-existing vitamin D deficiency. Methods and Study Design: A 12-week prospective cohort study was conducted in chemotherapy-naïve patients in two Australian locations with different sun exposure. Vitamin D deficiency was defined as ≤ 25 nmol/L and insufficiency 26-50 nmol/L 25(OH) D. Demographics, chemotherapy regimen, nutritional status, sun exposure, geographic location, and sea-son were collected at baseline, 6 and 12 weeks after commencing chemotherapy. Results: Eighty-five patients (μ55.3±13.4 years of age; 49% female) were recruited, 96% Caucasian. Fifty-four patients were treated with cura-tive intent (mostly for breast [n=29] or colorectal [n=12] cancers). At baseline, 10 patients were vitamin D defi-cient and 33 were insufficient. Mean serum 25(OH) D (nmol/L) was higher at latitude -27.5o (Brisbane) than lati-tude -34.9o (Adelaide) (μ61.9±22.1 vs μ42.2±19.2, p < 0.001) and varied according to season (spring: μ46.9±20.3, summer: μ50.8±18.2, autumn: μ76.4±25.2, winter: μ36.5±15.7, p < 0.001). Serum 25(OH) D decreased with chemotherapy (baseline: μ49.2±22.3, 6-weeks: μ40.9±19.0, 12-weeks: μ45.9±19.7, p=0.05), with a significant and more rapid decline in winter and autumn (p=0.03). Conclusions: Chemotherapy is associated with a decrease in serum vitamin D, particularly during winter and autumn. Investigations into the underlying mechanism and as-sociated potential outcomes with this decrease requires further investigation

    Protocol for developing core outcome sets for evaluation of psychosocial interventions for children and families with experience or at risk of child maltreatment or domestic abuse

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    Introduction Recognition that child maltreatment (CM) and domestic violence and abuse (DVA) are common and have serious and long-term adverse health consequences has resulted in policies and programmes to ensure that services respond to and safeguard children and their families. However, high-quality evidence about how services can effectively intervene is scant. The value of the current evidence base is limited partly because of the variety of outcomes and measures used in evaluative studies. One way of addressing this limitation is to develop a core outcome set (COS) which is measured and reported as a minimum standard in the context of trials and other types of evaluative research. The study described in this protocol aims to develop two discrete COSs for use in future evaluation of psychosocial interventions aimed at improving outcomes for children and families at risk or with experience of (1) CM or (2) DVA. Methods and analysis A two-phase mixed methods design: (1) rapid reviews of evidence, stakeholder workshops and semistructured interviews with adult survivors of CM/DVA and parents of children who have experienced CM/DVA and (2) a three panel adapted E-Delphi Study and consensus meeting. This study protocol adheres to reporting guidance for COS protocols and has been registered on the Core Outcome Measures for Effectiveness Trials (COMET) database. Ethics and dissemination We will disseminate our findings through peer-reviewed and open access publications, the COMET website and presentations at international conferences. We will engage with research networks, journal editors and funding agencies to promote awareness of the CM-COS and DVA-COS. We will work with advisory and survivor and public involvement groups to coproduce a range of survivor, policy and practice facing outputs. Approval for this study has been granted by the Research Ethics Committee at University College London

    Physiological Measures of Risk Perception in Highly Automated Driving

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    Highly automated driving will likely result in drivers being out-of-the-loop during specific scenarios and engaging in a wide range of non-driving related tasks. Manifesting in lower levels of risk perception to emerging events, and thus affect drivers' availability to take-over manual control in safety-critical scenarios. In this empirical research, we measured drivers' (N = 20) risk perception with cardiac and skin conductance indicators through a series of high-fidelity, simulated highly automated driving scenarios. By manipulating the presence of surrounding traffic and changing driving conditions as long-term risk modulators, and including a driving hazard event as a short-term risk modulator, we hypothesised that an increase in risk perception would induce greater physiological arousal. Our results demonstrate that heart rate variability features are superior at capturing arousal variations from these long-term, low to moderate risk scenarios. In contrast, skin conductance responses are more sensitive to rapidly evolving situations associated with moderate to high risk. Based on this research, future driver state monitoring systems should adopt multiple physiological measures to capture changes in the long and short term, modulation of risk perception. This will enable enhanced perception of driver readiness and improved availability to safely deal with take-over events when requested by an automated vehicle.</p
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