The bonding environment of chlorine in silicate melts

The local bonding environment of chlorine in silicate melts has a profound influence over the thermodynamic properties and structure of a melt, affecting the viscosity, rheology, and volatile degassing potential. To constrain the bonding environment of Cl in natural silicate melts, we have determined Cl K-edge X-ray absorption fine structure (XAFS) spectra for 44 experimentally produced silicate glasses in both the X-ray absorption near edge structure (XANES) and extended X-ray absorption fine structure (EXAFS) regions. In the pre-edge region, the presence of a pre-edge peak indicates covalent bonding of chlorine with silicon. Addition of divalent cations suppresses this pre-edge feature, and its centroid shifts to higher energy, indicating a change to increasingly more ionic bonding. In the XANES region the main absorption edge energy, E0, and the energy of maximum intensity, EMax, are also compositionally dependent. SiO2- rich glasses have relatively low values of E0 and EMax while the addition of 2+ ions increases both to values close to those found in the end-member chlorides CaCl2, MgCl2, and FeCl2. In two Na-rich glasses, E0 and EMax are close to corresponding energies in NaCl. It appears, therefore that bonding in the glasses is closely related to that found in the simple chlorides. This may be due to clustering which generates Ca[sbnd]Cl, Mg[sbnd]Cl, Fe[sbnd]Cl and Na[sbnd]Cl linkages either in the melts themselves or in the glasses due to rearrangements during quenching. The EXAFS parts of the glass spectra confirm the conclusions derived from the XANES region. These show that, as expected from the XANES region, addition of Ca and Fe2+ leads to R-space peaks which are closely related to those found in anhydrous CaCl2 and FeCl2 respectively. In order to determine if the spectra depend on pressure, temperature or chlorine fugacity of synthesis, 9 experiments were conducted using a single starting composition (Fe-free haplobasalt, An50Di28Fo22) across a range of temperatures (1300–1400 °C), pressures (5–20 kbar), chlorine fugacities (f(Cl2)) (1.38E−03 to 1.66E−06), and water contents (expected 0–8 wt% H2O). The results show that there is almost no change in the spectra across the XANES and EXAFS regions, indicating either that chlorine bonding is independent of the intensive parameters of the experiment or that all melts quench to glasses with the same local structure around the Cl atoms

SweetSpot: Near-Infrared Observations of Thirteen Type Ia Supernovae from a New NOAO Survey Probing the Nearby Smooth Hubble Flow

We present 13 Type Ia supernovae (SNe Ia) observed in the restframe near-infrared (NIR) from 0.02 < z < 0.09 with the WIYN High-resolution Infrared Camera (WHIRC) on the WIYN 3.5-m telescope. With only 1-3 points per light curve and a prior on the time of maximum from the spectrum used to type the object we measure an H-band dispersion of spectroscopically normal SNe Ia of 0.164 mag. These observations continue to demonstrate the improved standard brightness of SNe Ia in H-band even with limited data. Our sample includes two SNe Ia at z ~ 0.09, which represent the most distant restframe NIR H-band observations published to date. This modest sample of 13 NIR SNe Ia represent the pilot sample for "SweetSpot" - a three-year NOAO Survey program that will observe 144 SNe Ia in the smooth Hubble flow. By the end of the survey we will have measured the relative distance to a redshift of z ~ 0.05 to 1%. Nearby Type Ia supernova (SN Ia) observations such as these will test the standard nature of SNe Ia in the restframe NIR, allow insight into the nature of dust, and provide a critical anchor for future cosmological SN Ia surveys at higher redshift.Comment: 36 pages, 8 figures, Submitted to Ap

COVID-19 scenario modelling for the mitigation of capacity-dependent deaths in intensive care

Managing healthcare demand and capacity is especially difficult in the context of the COVID-19 pandemic, where limited intensive care resources can be overwhelmed by a large number of cases requiring admission in a short space of time. If patients are unable to access this specialist resource, then death is a likely outcome. In appreciating these ‘capacity-dependent’ deaths, this paper reports on the clinically-led development of a stochastic discrete event simulation model designed to capture the key dynamics of the intensive care admissions process for COVID-19 patients. With application to a large public hospital in England during an early stage of the pandemic, the purpose of this study was to estimate the extent to which such capacity-dependent deaths can be mitigated through demand-side initiatives involving non-pharmaceutical interventions and supply-side measures to increase surge capacity. Based on information available at the time, results suggest that total capacity-dependent deaths can be reduced by 75% through a combination of increasing capacity from 45 to 100 beds, reducing length of stay by 25%, and flattening the peak demand to 26 admissions per day. Accounting for the additional ‘capacity-independent’ deaths, which occur even when appropriate care is available within the intensive care setting, yields an aggregate reduction in total deaths of 30%. The modelling tool, which is freely available and open source, has since been used to support COVID-19 response planning at a number of healthcare systems within the UK National Health Service

Religious Freedom, Church–State Separation, and the Ministerial Exception

The Hosanna-Tabor case concerns the separation of church and state, an arrangement that is often misunderstood but is nevertheless a critical dimension of the freedom of religion protected by the First Amendment to our Constitution. For nearly a thousand years, the tradition of Western constitutionalism - the project of protecting political freedom by marking boundaries to the power of government - has been assisted by the principled commitment to religious liberty and to church-state separation, correctly understood. A community that respects - as ours does - both the importance of, and the distinction between, the spheres of political and religious authority is one in which the fundamental rights of all are more secure. A government that acknowledges this distinction, and the limits to its own reach, is one that will more consistently protect and vindicate the liberties of both individuals and institutions.The “ministerial exception,” at issue in Hosanna-Tabor, is a clear and crucial implication of religious liberty, church autonomy, and the separation of church and state. Because any worthwhile account of religious freedom would respect the authority of religious communities to select freely their own clergy, ministers, teachers, and doctrines, any such account must include something like the ministerial-exception rule. Reasonably constructed and applied, this rule helps civil decision-makers to avoid deciding essentially religious questions. In addition, and more importantly, it protects the fundamental freedom of religious communities to educate and form their members. Although the exception may, in some cases, block lawsuits against religious institutions and communities for discrimination, it rests on the overriding and foundational premise that there are some questions the civil courts do not have the power to answer, some wrongs that a constitutional commitment to church-state separation puts beyond the law’s corrective reach. The civil authority - that is, the authority of a constitutional government - lacks “competence” to intervene in such questions, not so much because they lie beyond its technical or intellectual capacity, but because they lie beyond its jurisdiction

Assessment and Mission Planning Capability For Quantitative Aerothermodynamic Flight Measurements Using Remote Imaging

High resolution calibrated infrared imagery of vehicles during hypervelocity atmospheric entry or sustained hypersonic cruise has the potential to provide flight data on the distribution of surface temperature and the state of the airflow over the vehicle. In the early 1980 s NASA sought to obtain high spatial resolution infrared imagery of the Shuttle during entry. Despite mission execution with a technically rigorous pre-planning capability, the single airborne optical system for this attempt was considered developmental and the scientific return was marginal. In 2005 the Space Shuttle Program again sponsored an effort to obtain imagery of the Orbiter. Imaging requirements were targeted towards Shuttle ascent; companion requirements for entry did not exist. The engineering community was allowed to define observation goals and incrementally demonstrate key elements of a quantitative spatially resolved measurement capability over a series of flights. These imaging opportunities were extremely beneficial and clearly demonstrated capability to capture infrared imagery with mature and operational assets of the US Navy and the Missile Defense Agency. While successful, the usefulness of the imagery was, from an engineering perspective, limited. These limitations were mainly associated with uncertainties regarding operational aspects of data acquisition. These uncertainties, in turn, came about because of limited pre-flight mission planning capability, a poor understanding of several factors including the infrared signature of the Shuttle, optical hardware limitations, atmospheric effects and detector response characteristics. Operational details of sensor configuration such as detector integration time and tracking system algorithms were carried out ad hoc (best practices) which led to low probability of target acquisition and detector saturation. Leveraging from the qualified success during Return-to-Flight, the NASA Engineering and Safety Center sponsored an assessment study focused on increasing the probability of returning spatially resolved scientific/engineering thermal imagery. This paper provides an overview of the assessment task and the systematic approach designed to establish confidence in the ability of existing assets to reliably acquire, track and return global quantitative surface temperatures of the Shuttle during entry. A discussion of capability demonstration in support of a potential Shuttle boundary layer transition flight test is presented. Successful demonstration of a quantitative, spatially resolved, global temperature measurement on the proposed Shuttle boundary layer transition flight test could lead to potential future applications with hypersonic flight test programs within the USAF and DARPA along with flight test opportunities supporting NASA s project Constellation

The First Data Release from SweetSpot: 74 Supernovae in 36 Nights on WIYN+WHIRC

SweetSpot is a three-year National Optical Astronomy Observatory (NOAO) Survey program to observe Type Ia supernovae (SNe Ia) in the smooth Hubble flow with the WIYN High-resolution Infrared Camera (WHIRC) on the WIYN 3.5-m telescope. We here present data from the first half of this survey, covering the 2011B-2013B NOAO semesters, and consisting of 493 calibrated images of 74 SNe Ia observed in the rest-frame near-infrared (NIR) from $0.02 < z < 0.09$. Because many observed supernovae require host galaxy subtraction from templates taken in later semesters, this release contains only the 186 NIR ($JHK_s$) data points for the 33 SNe Ia that do not require host-galaxy subtraction. The sample includes 4 objects with coverage beginning before the epoch of B-band maximum and 27 beginning within 20 days of B-band maximum. We also provide photometric calibration between the WIYN+WHIRC and Two-Micron All Sky Survey (2MASS) systems along with light curves for 786 2MASS stars observed alongside the SNe Ia. This work is the first in a planned series of three SweetSpot Data Releases. Future releases will include the full set of images from all 3 years of the survey, including host-galaxy reference images and updated data processing and host-galaxy reference subtraction. SweetSpot will provide a well-calibrated sample that will help improve our ability to standardize distance measurements to SNe Ia, examine the intrinsic optical-NIR colors of SNe Ia at different epochs, explore nature of dust in other galaxies, and act as a stepping stone for more distant, potentially space-based surveys.Comment: Published in AJ. 10 tables. 11 figures. Lightcurve plots included as a figureset and available in source tarball. Data online at http://www.phyast.pitt.edu/~wmwv/SweetSpot/DR1_data

A Comparison of Four Professional Groups\u27 Support for a Strengthened DUI Law

This study examined support patterns among criminal justice professionals for an enhanced DUI law. We surveyed North Dakota\u27s police, prosecutors, judges, and addiction counselors to measure their personal support and their perceptions of the support of others for the law. Respondents generally favored the strengthened law, but consistent with role theory, there were significant between group differences. There also were significant differences in personal versus perceived peer support and in perceived peer support versus the perceived support of other groups. Groups tended to agree in the differential levels of support they attributed to other groups. Implications for a coordinated system approach to combatting DUI are identified

Evolutionary conservation of residues in vertebrate DNA polymerase N conferring low fidelity and bypass activity

POLN is a nuclear A-family DNA polymerase encoded in vertebrate genomes. POLN has unusual fidelity and DNA lesion bypass properties, including strong strand displacement activity, low fidelity favoring incorporation of T for template G and accurate translesion synthesis past a 5S-thymine glycol (5S-Tg). We searched for conserved features of the polymerase domain that distinguish it from prokaryotic pol I-type DNA polymerases. A Lys residue (679 in human POLN) of particular interest was identified in the conserved ‘O-helix’ of motif 4 in the fingers sub-domain. The corresponding residue is one of the most important for controlling fidelity of prokaryotic pol I and is a nonpolar Ala or Thr in those enzymes. Kinetic measurements show that K679A or K679T POLN mutant DNA polymerases have full activity on nondamaged templates, but poorly incorporate T opposite template G and do not bypass 5S-Tg efficiently. We also found that a conserved Tyr residue in the same motif not only affects sensitivity to dideoxynucleotides, but also greatly influences enzyme activity, fidelity and bypass. Protein sequence alignment reveals that POLN has three specific insertions in the DNA polymerase domain. The results demonstrate that residues have been strictly retained during evolution that confer unique bypass and fidelity properties on POLN