1,094 research outputs found
Saturated fat enhances incorporation of n-3 polyunsaturated fatty acids into plasma and erythrocyte lipids in healthy humans
Distributed Generation and Resilience in Power Grids
We study the effects of the allocation of distributed generation on the
resilience of power grids. We find that an unconstrained allocation and growth
of the distributed generation can drive a power grid beyond its design
parameters. In order to overcome such a problem, we propose a topological
algorithm derived from the field of Complex Networks to allocate distributed
generation sources in an existing power grid.Comment: proceedings of Critis 2012 http://critis12.hig.no
Proteome phenotypes discriminate the growing location and malting traits in Field-Grown Barley
Barley is one of the key cereal grains for malting and brewing industries. However, climate variability and unprecedented weather events can impact barley yield and end-product quality. The genetic background and environmental conditions are key factors in defining the barley proteome content and malting characteristics. Here, we measure the barley proteome and malting characteristics of three barley lines grown in Western Australia, differing in genetic background and growing location, by applying liquid chromatography–mass spectrometry (LC–MS). Using data-dependent acquisition LC–MS, 1571 proteins were detected with high confidence. Quantitative data acquired using sequential window acquisition of all theoretical (SWATH) MS on barley samples resulted in quantitation of 920 proteins. Multivariate analyses revealed that the barley lines’ genetics and their growing locations are strongly correlated between proteins and desired traits such as the malt yield. Linking meteorological data with proteomic measurements revealed how high-temperature stress in northern regions affects seed temperature tolerance during malting, resulting in a higher malt yield. Our results show the impact of environmental conditions on the barley proteome and malt characteristics; these findings have the potential to expedite breeding programs and malt quality prediction
Successful Strategies for Promoting Self-Advocacy Among Students with LD: The LEAD Group
Students with learning disabilities (LD) often need to be taught self-determination skills to be better prepared for life after high school. This article describes the methods used by one school district to promote self-advocacy and self-awareness skills for students with LD. Through multicomponent group activities, students learned about their strengths and disabilities and how to advocate for their educational needs and rights. Advocacy skills were also applied to leadership roles, mentoring, and community education activities. Important features that contributed to the success of the program are described.Yeshttps://us.sagepub.com/en-us/nam/manuscript-submission-guideline
Risk of not being in employment, education or training (NEET) in late adolescence is signalled by school readiness measures at 4–5 years
Background
Not being in employment, education, or training (NEET) is associated with poor health (physical and mental) and social exclusion. We investigated whether England’s statutory school readiness measure conducted at 4–5 years provides a risk signal for NEET in late adolescence.
Methods
We identified 8,118 individuals with school readiness measures at 4–5 years and NEET records at 16–17 years using Connected Bradford, a bank of linked routinely collected datasets. Children were categorised as ‘school ready’ if they reached a ‘Good Level of Development’ on the Early Years Foundation Stage Profile. We used probit regression and structural equation modelling to investigate the relationship between school readiness and NEET status and whether it primarily relates to academic attainment.
Results
School readiness was significantly associated with NEET status. A larger proportion of young people who were not school ready were later NEET (11%) compared to those who were school ready (4%). Most of this effect was attributable to shared relationships with academic attainment, but there was also a direct effect. Measures of deprivation and Special Educational Needs were also strong predictors of NEET status.
Conclusions
NEET risk factors occur early in life. School readiness measures could be used as early indicators of risk, with interventions targeted to prevent the long-term physical and mental health problems associated with NEET, especially in disadvantaged areas. Primary schools are therefore well placed to be public health partners in early intervention strategies
Large-scale assessment of 7-11-year-olds’ cognitive and sensorimotor function within the Born in Bradford longitudinal birth cohort study [version 2; peer review: 3 approved, 1 approved with reservations]
Background: Cognitive ability and sensorimotor function are crucial aspects of children’s development, and are associated with physical and mental health outcomes and educational attainment. This paper describes cross-sectional sensorimotor and cognitive function data collected on over 15,000 children aged 7-10 years, collected as part of the Born in Bradford (BiB) longitudinal birth-cohort study. Methodological details of the large-scale data collection process are described, along with initial analyses of the data involving the relationship between cognition/sensorimotor ability and age and task difficulty, and associations between tasks.
Method: Data collection was completed in 86 schools between May 2016 and July 2019. Children were tested at school, individually, using a tablet computer with a digital stylus or finger touch for input. Assessments comprised a battery of three sensorimotor tasks (Tracking, Aiming, & Steering) and five cognitive tasks (three Working Memory tasks, Inhibition, and Processing Speed), which took approximately 40 minutes.
Results: Performance improved with increasing age and decreasing task difficulty, for each task. Performance on all three sensorimotor tasks was correlated, as was performance on the three working memory tasks. In addition, performance on a composite working memory score correlated with performance on both inhibition and processing speed. Interestingly, within age-group variation was much larger than between age-group variation.
Conclusions: The current project collected computerised measures of a range of cognitive and sensorimotor functions at 7-10 years of age in over 15,000 children. Performance varied as expected by age and task difficulty, and showed the predicted correlations between related tasks. Large within-age group variation highlights the need to consider the profile of individual children in studying cognitive and sensorimotor development. These data can be linked to the wider BiB dataset including measures of physical and mental health, biomarkers and genome-wide data, socio-demographic information, and routine data from local health and education services
A Statistical Study on the Morphology of Rays and Dynamics of Blobs in the Wake of Coronal Mass Ejections
In this paper, with a survey through the Large Angle and Spectrometric
Coronagraph (LASCO) data from 1996 to 2009, we present 11 events with plasma
blobs flowing outwards sequentially along a bright coronal ray in the wake of a
coronal mass ejection. The ray is believed to be associated with the current
sheet structure that formed as a result of solar eruption, and the blobs are
products of magnetic reconnection occurring along the current sheet. The ray
morphology and blob dynamics are investigated statistically. It is found that
the apparent angular widths of the rays at a fixed time vary in a range of
2.1-6.6 (2.0-4.4) degrees with an average of 3.5 (2.9) degrees at 3 (4) Rs,
respectively, and the observed durations of the events vary from 12 h to a few
days with an average of 27 h. It is also found, based on the analysis of blob
motions, that 58% (26) of the blobs were accelerated, 20% (9) were decelerated,
and 22% (10) moved with a nearly-constant speed. Comparing the dynamics of our
blobs and those that are observed above the tip of a helmet streamer, we find
that the speeds and accelerations of the blobs in these two cases differ
significantly. It is suggested that these differences of the blob dynamics stem
from the associated magnetic reconnection involving different magnetic field
configurations and triggering processes.Comment: 12 pages, 6 figures, accepted by Solar Physic
Effect of Solar Wind Drag on the Determination of the Properties of Coronal Mass Ejections from Heliospheric Images
The Fixed-\Phi (F\Phi) and Harmonic Mean (HM) fitting methods are two methods
to determine the average direction and velocity of coronal mass ejections
(CMEs) from time-elongation tracks produced by Heliospheric Imagers (HIs), such
as the HIs onboard the STEREO spacecraft. Both methods assume a constant
velocity in their descriptions of the time-elongation profiles of CMEs, which
are used to fit the observed time-elongation data. Here, we analyze the effect
of aerodynamic drag on CMEs propagating through interplanetary space, and how
this drag affects the result of the F\Phi and HM fitting methods. A simple drag
model is used to analytically construct time-elongation profiles which are then
fitted with the two methods. It is found that higher angles and velocities give
rise to greater error in both methods, reaching errors in the direction of
propagation of up to 15 deg and 30 deg for the F\Phi and HM fitting methods,
respectively. This is due to the physical accelerations of the CMEs being
interpreted as geometrical accelerations by the fitting methods. Because of the
geometrical definition of the HM fitting method, it is affected by the
acceleration more greatly than the F\Phi fitting method. Overall, we find that
both techniques overestimate the initial (and final) velocity and direction for
fast CMEs propagating beyond 90 deg from the Sun-spacecraft line, meaning that
arrival times at 1 AU would be predicted early (by up to 12 hours). We also
find that the direction and arrival time of a wide and decelerating CME can be
better reproduced by the F\Phi due to the cancellation of two errors:
neglecting the CME width and neglecting the CME deceleration. Overall, the
inaccuracies of the two fitting methods are expected to play an important role
in the prediction of CME hit and arrival times as we head towards solar maximum
and the STEREO spacecraft further move behind the Sun.Comment: Solar Physics, Online First, 17 page
Speeds and arrival times of solar transients approximated by self-similar expanding circular fronts
The NASA STEREO mission opened up the possibility to forecast the arrival
times, speeds and directions of solar transients from outside the Sun-Earth
line. In particular, we are interested in predicting potentially geo-effective
Interplanetary Coronal Mass Ejections (ICMEs) from observations of density
structures at large observation angles from the Sun (with the STEREO
Heliospheric Imager instrument). We contribute to this endeavor by deriving
analytical formulas concerning a geometric correction for the ICME speed and
arrival time for the technique introduced by Davies et al. (2012, ApJ, in
press) called Self-Similar Expansion Fitting (SSEF). This model assumes that a
circle propagates outward, along a plane specified by a position angle (e.g.
the ecliptic), with constant angular half width (lambda). This is an extension
to earlier, more simple models: Fixed-Phi-Fitting (lambda = 0 degree) and
Harmonic Mean Fitting (lambda = 90 degree). This approach has the advantage
that it is possible to assess clearly, in contrast to previous models, if a
particular location in the heliosphere, such as a planet or spacecraft, might
be expected to be hit by the ICME front. Our correction formulas are especially
significant for glancing hits, where small differences in the direction greatly
influence the expected speeds (up to 100-200 km/s) and arrival times (up to two
days later than the apex). For very wide ICMEs (2 lambda > 120 degree), the
geometric correction becomes very similar to the one derived by M\"ostl et al.
(2011, ApJ, 741, id. 34) for the Harmonic Mean model. These analytic
expressions can also be used for empirical or analytical models to predict the
1 AU arrival time of an ICME by correcting for effects of hits by the flank
rather than the apex, if the width and direction of the ICME in a plane are
known and a circular geometry of the ICME front is assumed.Comment: 15 pages, 5 figures, accepted for publication in "Solar Physics
Possible origins of macroscopic left-right asymmetry in organisms
I consider the microscopic mechanisms by which a particular left-right (L/R)
asymmetry is generated at the organism level from the microscopic handedness of
cytoskeletal molecules. In light of a fundamental symmetry principle, the
typical pattern-formation mechanisms of diffusion plus regulation cannot
implement the "right-hand rule"; at the microscopic level, the cell's
cytoskeleton of chiral filaments seems always to be involved, usually in
collective states driven by polymerization forces or molecular motors. It seems
particularly easy for handedness to emerge in a shear or rotation in the
background of an effectively two-dimensional system, such as the cell membrane
or a layer of cells, as this requires no pre-existing axis apart from the layer
normal. I detail a scenario involving actin/myosin layers in snails and in C.
elegans, and also one about the microtubule layer in plant cells. I also survey
the other examples that I am aware of, such as the emergence of handedness such
as the emergence of handedness in neurons, in eukaryote cell motility, and in
non-flagellated bacteria.Comment: 42 pages, 6 figures, resubmitted to J. Stat. Phys. special issue.
Major rewrite, rearranged sections/subsections, new Fig 3 + 6, new physics in
Sec 2.4 and 3.4.1, added Sec 5 and subsections of Sec
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