4,157 research outputs found
Steam gasification of rapeseed, wood, sewage sludge and miscanthus biochars for the production of a hydrogen-rich syngas
Steam gasification of biochars has emerged as a promising method for generating syngas that is rich in hydrogen. In this study four biochars formed via intermediate pyrolysis (wood pellet, sewage sludge, rapeseed and miscanthus) were gasified in a quartz tubular reactor using steam. The dynamic behaviour of the process and effects of temperature, steam flow and particle size were studied. The results show that increases in both steam flow and temperature significantly increase the dry gas yield and carbon conversion, but hydrogen volume fraction decreases at higher temperatures whilst particle size has little effect on gaseous composition. The highest volume fraction of hydrogen, 58.7%, was obtained at 750 °C from the rapeseed biochar
Warm dust in the terrestrial planet zone of a sun-like Pleiad: collisions between planetary embryos?
Only a few solar-type main sequence stars are known to be orbited by warm
dust particles; the most extreme is the G0 field star BD+20 307 that emits ~4%
of its energy at mid-infrared wavelengths. We report the identification of a
similarly dusty star HD 23514, an F6-type member of the Pleiades cluster. A
strong mid-IR silicate emission feature indicates the presence of small warm
dust particles, but with the primary flux density peak at the non-standard
wavelength of ~9 micron. The existence of so much dust within an AU or so of
these stars is not easily accounted for given the very brief lifetime in orbit
of small particles. The apparent absence of very hot (>~1000 K) dust at both
stars suggests the possible presence of a planet closer to the stars than the
dust. The observed frequency of the BD+20 307/HD 23514 phenomenon indicates
that the mass equivalent of Earth's Moon must be converted, via collisions of
massive bodies, to tiny dust particles that find their way to the terrestrial
planet zone during the first few hundred million years of the life of many
(most?) sun-like stars. Identification of these two dusty systems among
youthful nearby solar-type stars suggests that terrestrial planet formation is
common.Comment: ApJ in press, 19 pages including 3 figures and 2 tables, minor
changes to the tables and figure
Resolution of Clinical Signs of Ventilator-Associated Pneumonia in Trauma Patients
Objectives: The ATS/IDSA Ventilator-Associated Pneumonia (VAP) guidelines suggest that clinical improvement of VAP should be apparent within 3–6 days. This study evaluated resolution of clinical signs of VAP in trauma patients after diagnosis.
Methods: Critically injured adults admitted to the trauma intensive care unit (ICU) from June 1, 2006, to December 31, 2007, and subsequently given a diagnosis of VAP were retrospectively assessed. Clinical signs, including derangements of maximum temperature (Tmax), white blood cell (WBC) count, and PaO2/FiO2, were evaluated on days 1–16 after VAP diagnosis. Data are presented as mean ± SD unless otherwise stated. Clinical parameters after VAP were compared using repeated-measures ANOVA with the Tukey test for multiple comparisons.
Results: A total of 82 patients were identified. Data for the 34 patients without concurrent infections are presented. Demographic data include: Age 46 ± 17 years; 71% men; 94% blunt trauma; median (IQR) Injury Severity Score 29.5 (24–38); duration of mechanical ventilation 33 ± 27 days; ICU length of stay (LOS) 39 ± 25 days; hospital LOS 53 ± 33 days. Clinical signs following VAP diagnosis: Tmax (°F): Day 1=101.8 ± 1.3, Day 3=101.1 ± 1.1, Day 6=101.1 ± 1.4, Day 16=100.1 ± 3. Compared to Day 1, there was a significant reduction in Tmax at days 10, 11, 12, 13, 14, and 16 (p\u3c0.05 for all). WBC count (cells per microliter): day 1 = 12.9 ± 5, day 3 = 13.7 ± 5, day 6 = 14.4 ± 5, and day 16 = 13.8 ± 6. There was no significant difference in WBC on days 1–16 (p=0.42). PaO2/FiO2: day 1 = 232 ± 108, day 3 = 200 ± 87, day 6 = 218 ± 104, day 16 = 246 ± 126. Differences in PaO2/FiO2 on days 1–16 did not reach statistical significance (p=0.06).
Conclusion: Improvement of clinical parameters after a VAP diagnosis is delayed in trauma patients. Alternative methods for determining resolution should be investigated. Published in To be published in Critical Care Medicine’s December 2009 supplement
cDNA-RNA subtractive hybridization reveals increased expression of mycocerosic acid synthase in intracellular Mycobacterium bovis BCG.
Identifying genes that are differentially expressed by Mycobacterium bovis BCG after phagocytosis by macrophages will facilitate the understanding of the molecular mechanisms of host cell-intracellular pathogen interactions. To identify such genes a cDNA-total RNA subtractive hybridization strategy has been used that circumvents the problems both of limited availability of bacterial RNA from models of infection and the high rRNA backgrounds in total bacterial RNA. The subtraction products were used to screen a high-density gridded Mycobacterium tuberculosis genomic library. Sequence data were obtained from 19 differential clones, five of which contained overlapping sequences for the gene encoding mycocerosic acid synthase (mas). Mas is an enzyme involved in the synthesis of multi-methylated long-chain fatty acids that are part of phthiocerol dimycocerosate, a major component of the complex mycobacterial cell wall. Northern blotting and primer extension data confirmed up-regulation of mas in intracellular mycobacteria and also revealed a putative extended -10 promoter structure and a long untranslated upstream region 5' of the mas transcripts, containing predicted double-stranded structures. Furthermore, clones containing overlapping sequences for furB, groEL-2, rplE and fadD28 were identified and the up-regulation of these genes was confirmed by Northern blot analysis. The cDNA-RNA subtractive hybridization enrichment and high density gridded library screening, combined with selective extraction of bacterial mRNA represents a valuable approach to the identification of genes expressed during intra-macrophage residence for bacteria such as M. bovis BCG and the pathogenic mycobacterium, M. tuberculosis
Resolution of Clinical Signs in Trauma Intensive Care Unit Patients Following Diagnosis of Ventilator-Associated Pneumonia
PURPOSE: The ATS/IDSA Ventilator-Associated Pneumonia (VAP) guidelines suggest that clinical improvement of VAP should be apparent within 3-6 days. Anecdotally, such improvement has not been noted in trauma patients at our institution. The current study was conducted to evaluate resolution of clinical signs of VAP following diagnosis.
METHODS: Critically injured adults admitted to the trauma intensive care unit (TICU) from 6/1/06-12/31/07 and subsequently diagnosed with VAP were retrospectively reviewed. Clinical signs, including derangements of maximum temperature (Tmax), white blood cell (WBC) count and Pa02/FiO2, were evaluated on days 1-16 following VAP diagnosis. Data are presented as mean ± SD unless otherwise stated. Clinical parameters following VAP were compared using repeated measures ANOVA with the Tukey test for multiple comparisons.
RESULTS: A total of 82 patients were identified. Data for the 34 patients without concurrent infections are presented. Demographic data include: Age 46 ± 17 years; 71% males; 94% blunt trauma; median (IQR) Injury Severity Score 29.5 (24 to 38); duration of mechanical ventilation 33 ± 27 days; ICU length of stay (LOS) 39 ± 25 days; hospital LOS 53 ± 33 days. Clinical signs following VAP diagnosis (Figure): Tmax (°F): Day 1=101.8 ± 1.3, Day 3=101.1 ± 1.1, Day 6=101.1 ± 1.4, Day 16=100.1 ± 3. Compared to Day 1, there was a significant reduction in Tmax at Days 10, 11, 12, 13, 14 and 16 (p \u3c 0.05 for all). WBC count (cells/μL): Day 1=12.9 ± 5, Day 3=13.7 ± 5, Day 6=14.4 ± 5, Day 16=13.8 ± 6. There was no significant difference in WBC count on Days 1-16 (p=0.42). PaO2/FiO2: Day 1=232 ± 108, Day 3=200 ± 87, Day 6=218 ± 104, Day 16=246 ± 126. Differences in PaO2/FiO2 on Days 1-16 did not reach statistical significance (p=0.06).
CONCLUSIONS: In trauma patients, improvement of clinical parameters following diagnosis of VAP is delayed beyond the 3-6 day timeframe suggested in the ATS/IDSA guidelines. Alternative methods for determining resolution of VAP in trauma patients should be investigated. METHODS INTRODUCTIO
A Blind Search for Magnetospheric Emissions from Planetary Companions to Nearby Solar-type Stars
This paper reports a blind search for magnetospheric emissions from planets
around nearby stars. Young stars are likely to have much stronger stellar winds
than the Sun, and because planetary magnetospheric emissions are powered by
stellar winds, stronger stellar winds may enhance the radio luminosity of any
orbiting planets. Using various stellar catalogs, we selected nearby stars (<~
30 pc) with relatively young age estimates (< 3 Gyr). We constructed different
samples from the stellar catalogs, finding between 100 and several hundred
stars. We stacked images from the 74-MHz (4-m wavelength) VLA Low-frequency Sky
Survey (VLSS), obtaining 3\sigma limits on planetary emission in the stacked
images of between 10 and 33 mJy. These flux density limits correspond to
average planetary luminosities less than 5--10 x 10^{23} erg/s. Using recent
models for the scaling of stellar wind velocity, density, and magnetic field
with stellar age, we estimate scaling factors for the strength of stellar
winds, relative to the Sun, in our samples. The typical kinetic energy carried
by the stellar winds in our samples is 15--50 times larger than that of the
Sun, and the typical magnetic energy is 5--10 times larger. If we assume that
every star is orbited by a Jupiter-like planet with a luminosity larger than
that of the Jovian decametric radiation by the above factors, our limits on
planetary luminosities from the stacking analysis are likely to be a factor of
10--100 above what would be required to detect the planets in a statistical
sense. Similar statistical analyses with observations by future instruments,
such as the Low Frequency Array (LOFAR) and the Long Wavelength Array (LWA),
offer the promise of improvements by factors of 10--100.Comment: 11 pages; AASTeX; accepted for publication in A
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Single-Layer Deposits of Nickel Base Superalloy by Means of Selective Laser Sintering
Single layer deposits consisting of Mar-M 247 powder were consolidated on
Alloy 718 polycrystalline flat sheets by means of the Selective Laser Melting (SLM)
technique. The deposition process consisted in selectively fusing a powder bed precompacted using of an insulating non-wettable mask trough. The mask-powder-substrate
arrangement was pre-heated inside a processing chamber under high vacuum. An inertreducing atmosphere was applied, and a focused Nd:YAG laser beam was then raster
scanned at high speed along the contour of the trough, providing energy to induce a
melting front to propagate along the powder as well as over the surface of the plate. As
the laser beam moved forward a solidification front was left behind with a metallurgical
bond between the substrate and the deposited layer. Optical microscopy revealed that
epitaxial growth occurred in the [001] direction from the melted substrate to about half
the height of the deposits. Above that height, the [001] dendritic front bowed towards the
[100] direction. A dendritic-equiaxed transition appeared near the free surface of the
deposit. These results indicate that the SLM technique could have potential application
for growing single crystal structures as well as in repairing damaged or worn turbine
blades.Funding for this project was provided by Rolls-Royce North America and the
University of Texas at Austin.Mechanical Engineerin
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