High-dimensional Bell test for a continuous variable state in phase space and its robustness to detection inefficiency

We propose a scheme for testing high-dimensional Bell inequalities in phase space. High-dimensional Bell inequalities can be recast into the forms of a phase-space version using quasiprobability functions with the complex-valued order parameter. We investigate their violations for two-mode squeezed states while increasing the dimension of measurement outcomes, and finally show the robustness of high-dimensional tests to detection inefficiency.Comment: 8 pages, 2 figures; title and abstract changed, published versio

Performance of a family of omni and steered antennas for mobile satellite applications

The design and performance of a family of vehicle antennas developed at JPL in support of an emerging US Mobile Satellite Service (MSS) system are described. Test results of the antennas are presented. Trends for future development are addressed. Recommendations on design approaches for vehicle antennas of the first generation MSS are discussed

Testing quantum nonlocality by generalized quasiprobability functions

We derive a Bell inequality based on a generalized quasiprobability function which is parameterized by one non-positive real value. Two types of known Bell inequalities formulated in terms of the Wigner and Q functions are included as limiting cases. We investigate violations of our Bell inequalities for single photon entangled states and two-mode squeezed vacuum states when varying the detector efficiency. We show that the Bell inequality for the Q function allows the lowest detection efficiency for violations of local realism.Comment: 6 pages, 3 figure

NOD2/RICK-dependent β-defensin 2 regulation is protective for nontypeable Haemophilus influenzae-induced middle ear infection.

Middle ear infection, otitis media (OM), is clinically important due to the high incidence in children and its impact on the development of language and motor coordination. Previously, we have demonstrated that the human middle ear epithelial cells up-regulate β-defensin 2, a model innate immune molecule, in response to nontypeable Haemophilus influenzae (NTHi), the most common OM pathogen, via TLR2 signaling. NTHi does internalize into the epithelial cells, but its intracellular trafficking and host responses to the internalized NTHi are poorly understood. Here we aimed to determine a role of cytoplasmic pathogen recognition receptors in NTHi-induced β-defensin 2 regulation and NTHi clearance from the middle ear. Notably, we observed that the internalized NTHi is able to exist freely in the cytoplasm of the human epithelial cells after rupturing the surrounding membrane. The human middle ear epithelial cells inhibited NTHi-induced β-defensin 2 production by NOD2 silencing but augmented it by NOD2 over-expression. NTHi-induced β-defensin 2 up-regulation was attenuated by cytochalasin D, an inhibitor of actin polymerization and was enhanced by α-hemolysin, a pore-forming toxin. NOD2 silencing was found to block α-hemolysin-mediated enhancement of NTHi-induced β-defensin 2 up-regulation. NOD2 deficiency appeared to reduce inflammatory reactions in response to intratympanic inoculation of NTHi and inhibit NTHi clearance from the middle ear. Taken together, our findings suggest that a cytoplasmic release of internalized NTHi is involved in the pathogenesis of NTHi infections, and NOD2-mediated β-defensin 2 regulation contributes to the protection against NTHi-induced otitis media

Excitation spectroscopy of vortex lattices in a rotating Bose-Einstein condensate

Excitation spectroscopy of vortex lattices in rotating Bose-Einstein condensates is described. We numerically obtain the Bogoliubov-deGenne quasiparticle excitations for a broad range of energies and analyze them in the context of the complex dynamics of the system. Our work is carried out in a regime in which standard hydrodynamic assumptions do not hold, and includes features not readily contained within existing treatments.Comment: 4 pages, 4 figures. Submitted for publicatio

Ability of γδ T cells to modulate the Foxp3 T cell response is dependent on adenosine.

Whether γδ T cells inhibit or enhance the Foxp3 T cell response depends upon their activation status. The critical enhancing effector in the supernatant is adenosine. Activated γδ T cells express adenosine receptors at high levels, which enables them to deprive Foxp3+ T cells of adenosine, and to inhibit their expansion. Meanwhile, cell-free supernatants of γδ T cell cultures enhance Foxp3 T cell expansion. Thus, inhibition and enhancement by γδ T cells of Foxp3 T cell response are a reflection of the balance between adenosine production and absorption by γδ T cells. Non-activated γδ T cells produce adenosine but bind little, and thus enhance the Foxp3 T cell response. Activated γδ T cells express high density of adenosine receptors and have a greatly increased ability to bind adenosine. Extracellular adenosine metabolism and expression of adenosine receptor A2ARs by γδ T cells played a major role in the outcome of γδ and Foxp3 T cell interactions. A better understanding of the functional conversion of γδ T cells could lead to γδ T cell-targeted immunotherapies for related diseases

Moment Rotation Behavior for Concrete Filled SHS Column to Composite Beam Connections

A series of connection tests were carried out to study the behavior of connections between concrete filled Square Hollow Section(SHS) columns and composite W-section beams. The test connections were four different semi-rigid types selected for application to multi -story building frames. The initial flexural rigidities were estimated by different theories and compared with the simple beam. Moment-roration relations were simulated using a finite element program and a simple power model was proposed to predict the moment-rotation behavior of connections