The Impact of R&D on the Singapore Economy:An Empirical Evaluation

Much of the literature on the impact of R&D on economic performance is founded on the advanced countries, where the intensity of R&D expenditure has been relatively high and stable for many years. In this paper, we provide empirical estimates of the impact of R&D on the economic growth of a Newly Industrialised Economy, Singapore, where R&D expenditure intensity has been low initially, bur rising rapidly in recent years. The Cobb-Douglas based analysis provided empirical evidence that R&D investment in Singapore had a significant impact on its total factor productivity performance in the last 20 years and established a long-term equilibrium relationship between R&D investments and TFP. However, compared to the OECD nations, the impact of R&D investment on economic growth in Singapore is not as strong, as evidenced by lower estimated elasticity values. The long run elasticity of output with respect to R&D was computed to be 8.1% for Singapore compared to long run elasticities of over 10% estimated by other researchers for OECD countries. This suggests that Singapore still has some way to go in catching up with the advanced nations in terms of R&D productivity. This not only means increasing the level of R&D intensity in Singapore but also more efficient exploitation of domestic R&D activity.Economic Growth, R&D Expenditure, Total Factor Productivity

Combating plagiarism in the classroom / Wong Soon Heng

As plagiarism is a perennial problem among university students, there is a wealth of literature on this issue. In this paper, the authors share some of the practices they have adopted to combat the plagiarism problem such as teaching paraphrasing and referencing skills, requiring multiple drafts and authenticity statements. Feedback from students has shown that they find these practices useful to help them use sources ethically

A preliminary study on cultivation of Mucor plumbeus: For microbial oil production using molasses

Sugarcane molasses, sugarcane trash and bagasse are the major by-products generated in cane sugar production process. Conversion of these by -products into valuable products has the potential to improve the profitability of the sugarcane industry. Biofuels are one of the value- added products. However, the profits from the production of low value biofuels such as bioethanol and biodiesel are marginal under current market conditions . In recent years, production of high value advanced drop- in biofuels from renewable carbohydrate feedstocks has gained increasing interests worldwide. The research team at QUT is working together with industrial partners on advanced biofuels production from sugarcane processing by-products through a two-stage process. In the first stage, microbial oils are prod uced by oleaginous microorganisms . In the second stage, advanced biofuels are produced through hydro deoxygenation of either microbial oils extracted from microbial biomass or microbial oils obtained from hydrothermal liquefaction of microbial biomass. In this study, microbial oil production by an oleaginous filamentous fungus , Mucorplumbeus , was carried out using molasses as a carbon source. Morphology control strategy and nutrient optimisation were firstly developed to improve biomass and microbial oil production. Furthermore, microbial oil production by M. plumbeus was scaled up from shake flasks to laboratory scale stirred tank reactors . Inoculation of crushed fungal pellet biomass led to the formation of dispersed short hyphae in reactors and improved biomass and oil production. Finally, the inoculation strategy was demonstrated in a 1 000 L reactor at Mackay Renewable Biocommodity Pilot Plant

PTEN/Akt Signaling Controls Mitochondrial Respiratory Capacity through 4E-BP1

10.1371/journal.pone.0045806PLoS ONE79

Intrathecal Morphine and Post-Operative Pain Relief in Robotic Surgeries : A Systematic Review and Meta-Analysis

Peer reviewedPublisher PD

Determination of borneol and other chemical compounds of essential oil of Dryobalanops aromatica exudate from Malaysia

Purpose: To determine borneol and other chemical compounds of essential oil derived from the exudate of Dryobalanops aromatica in Malaysia.Methods: Exudate was collected from D. aromatica and subjected to fractional distillation to obtain essential oil. Gas chromatography-mass spectrometry (GC-MS) was performed to characterize the composition of the isolated essential oil.Results: Essential oil (7.58 %) was obtained with the highest yield (3.24 %) in the first 2 h of fractional distillation. Thirty compounds which accounted for 97.56 % of total essential oil composition were identified by GC-MS, and they include sesquiterpenes (46.87 %), monoterpenes (31.05 %), oxygenated monoterpenes (16.76 %) and oxygenated sesquiterpenes (2.13 %). Borneol (0.74 %) was also detected in the essential oil.Conclusion: Borneol and other terpenoid compounds are present in the essential oil of the exudate of D. aromatica.Keywords: Exudate, Dryobalanops Aromatica, Fractional distillation, Essential oil, Gaschromatography-mass spectrometry, Borneo

Chemical composition of essential oil of exudates of Dryobalanops aromatica

Purpose: To identify the chemical composition of essential oil from the exudates of Dryobalanops aromatica from Malaysia.Methods: Exudate was collected from D. aromatica and subjected to fractional  distillation to obtain essential oil. Gas chromatography-mass spectrometry  (GC-MS) was used to characterize the composition of the isolated essential oil.Results: The yield of essential oil was 7.58 %, with the highest yield (3.24 %) within the first 2 h of fractional distillation. Thirty compounds which accounted for 97.56 % of essential oil composition were identified. These include sesquiterpenes (46.87 %), monoterpenes (31.05 %), oxygenated monoterpenes (16.76 %) and oxygenated  sesquiterpenes (2.13 %). Borneol accounted for 0.74 % of the essential oil.Conclusion: Essential oil from the exudates of D. aromatica contains terpenoid  compounds and borneol.Keywords: Dryobalanops aromatica, exudate, fractional distillation, essential oil, GS-MS, borneo

Potential enhancement of post-stroke angiogenic response by targeting the oligomeric aggregation of p53 protein

Tumor suppressor gene p53 and its aggregate have been found to be involved in many angiogenesis-related pathways. We explored the possible p53 aggregation formation mechanisms commonly occur after ischemic stroke, such as hypoxia and the presence of reactive oxygen species (ROS). The angiogenic pathways involving p53 mainly occur in nucleus or cytoplasm, with one exception that occurs in mitochondria. Considering the high mitochondrial density in brain and endothelial cells, we proposed that the cyclophilin D (CypD)-dependent vascular endothelial cell (VECs) necrosis pathway occurring in the mitochondria is one of the major factors that affects angiogenesis. Hence, targeting p53 aggregation, a key intermediate in the pathway, could be an alternative therapeutic target for post-stroke management

Observation of electron-antineutrino disappearance at Daya Bay

The Daya Bay Reactor Neutrino Experiment has measured a non-zero value for the neutrino mixing angle $\theta_{13}$ with a significance of 5.2 standard deviations. Antineutrinos from six 2.9 GW$_{\rm th}$ reactors were detected in six antineutrino detectors deployed in two near (flux-weighted baseline 470 m and 576 m) and one far (1648 m) underground experimental halls. With a 43,000 ton-GW_{\rm th}-day livetime exposure in 55 days, 10416 (80376) electron antineutrino candidates were detected at the far hall (near halls). The ratio of the observed to expected number of antineutrinos at the far hall is $R=0.940\pm 0.011({\rm stat}) \pm 0.004({\rm syst})$. A rate-only analysis finds $\sin^22\theta_{13}=0.092\pm 0.016({\rm stat})\pm0.005({\rm syst})$ in a three-neutrino framework.Comment: 5 figures. Version to appear in Phys. Rev. Let