5,130 research outputs found

    Mechanisms for Direct Breakup Reactions

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    We review some simple mechanisms of breakup in nuclear reactions. We mention the spectator breakup, which is described in the post-form DWBA. The relation to other formulations is also indicated. An especially important mechanism is Coulomb dissociation. It is a distinct advantage that the perturbation due to the electric field of the nucleus is exactly known. Therefore firm conclusions can be drawn from such measurements. Some new applications of Coulomb dissociation for nuclear astrophysics are discussed.Comment: 17 pages, 5 figures, to appear in the proceedings of the RCNP-TMU Symposium on Spins in Nuclear and Hadronic Reactions, October 16-18 199

    An important role for Myb-MuvB and its target gene KIF23 in a mouse model of lung adenocarcinoma

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    The conserved Myb-MuvB (MMB) multiprotein complex has an important role in transcriptional activation of mitotic genes. MMB target genes are overexpressed in several different cancer types and their elevated expression is associated with an advanced tumor state and a poor prognosis. This suggests that MMB could contribute to tumorigenesis by mediating overexpression of mitotic genes. However, although MMB has been extensively characterized biochemically, the requirement for MMB in tumorigenesis in vivo has not been investigated. Here we demonstrate that MMB is required for tumor formation in a mouse model of lung cancer driven by oncogenic K-RAS. We also identify a requirement for the mitotic kinesin KIF23, a key target gene of MMB, in tumorigenesis. RNA interference-mediated depletion of KIF23 inhibited lung tumor formation in vivo and induced apoptosis in lung cancer cell lines. Our results suggest that inhibition of KIF23 could be a strategy for treatment of lung cancer

    Inzicht en toezicht: controle in de kennissamenleving

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    Nieuwe technieken maken het opslaan en verwerken van informatie eenvoudiger. Sterker\ud nog: ze maken de weg vrij om gegevens vast te leggen voordat duidelijk is welk inzicht\ud we eigenlijk nastreven. Toezicht wint zo terrein ten opzichte van de kennisverwerving.\ud \ud Voorbeelden van toenemend toezicht zijn elektronische dossiers over burgers,\ud informatievergaring door de politie en in private initiatieven zoals Google Earth. Deze\ud systemen maken het mogelijk om op grote schaal verbanden te ontdekken en afwijkingen op\ud te sporen, zonder dat er duidelijke kennisvragen aan vooraf gaan.\ud \ud De relatie tussen inzicht en toezicht is bepalend voor hoe we met de verzamelde kennis\ud omgaan. Ligt de nadruk daarbij op inzicht, overzicht, toezicht, of nog iets anders? Dit\ud Jaarboek Kennissamenleving 2010 stelt kritische vragen bij de alomtegenwoordige blik van\ud toezicht. Het draagt ideeën aan om deze in de toekomst anders te richten, zodat inzicht en\ud toezicht in balans kunnen blijven

    Symmetry energy of dilute warm nuclear matter

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    The symmetry energy of nuclear matter is a fundamental ingredient in the investigation of exotic nuclei, heavy-ion collisions and astrophysical phenomena. New data from heavy-ion collisions can be used to extract the free symmetry energy and the internal symmetry energy at subsaturation densities and temperatures below 10 MeV. Conventional theoretical calculations of the symmetry energy based on mean-field approaches fail to give the correct low-temperature, low-density limit that is governed by correlations, in particular by the appearance of bound states. A recently developed quantum statistical (QS) approach that takes the formation of clusters into account predicts symmetry energies that are in very good agreement with the experimental data. A consistent description of the symmetry energy is given that joins the correct low-density limit with quasiparticle approaches valid near the saturation density.Comment: 4 pages, 2 figures, 1 tabl

    Features of water chemical composition of oligotrophic and eutrophic bogs in the South of the Tomsk region

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    On the basis of the actual material the analysis of chemical composition of bog waters in the territory of the South of the Tomsk region is carried out. The data on average concentration of macro and trace components, organic matter, pH of bog waters are obtained. Significant distinctions in a chemical composition of surface water for different types of bogs are revealed. The composition and macrostructure of humic acids by the example of eutrophic bogs is studied

    Dirac-Brueckner Hartree-Fock Approach: from Infinite Matter to Effective Lagrangians for Finite Systems

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    One of the open problems in nuclear structure is how to predict properties of finite nuclei from the knowledge of a bare nucleon-nucleon interaction of the meson-exchange type. We point out that a promising starting point consists in Dirac-Brueckner-Hartree-Fock (DBHF) calculations us- ing realistic nucleon-nucleon interactions like the Bonn potentials, which are able to reproduce satisfactorily the properties of symmetric nuclear matter without the need for 3-body forces, as is necessary in non-relativistic BHF calculations. However, the DBHF formalism is still too com- plicated to be used directly for finite nuclei. We argue that a possible route is to define effective Lagrangians with density-dependent nucleon-meson coupling vertices, which can be used in the Relativistic Hartree (or Relativistic Mean Field (RMF)) or preferrably in the Relativistic Hartree- Fock (RHF) approach. The density-dependence is matched to the nuclear matter DBHF results. We review the present status of nuclear matter DBHF calculations and discuss the various schemes to construct the self-energy, which lead to differences in the predictions. We also discuss how effective Lagrangians have been constructed and are used in actual calculations. We point out that completely consistent calculations in this scheme still have to be performed.Comment: 16 pages, to be published in Journal of Physics G: Nuclear and Particle Physics, special issue

    Dilution of the magnetic lattice in the Kitaev candidate α\alpha-RuCl3_3 by Rh3+^{3+} doping

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    Magnetic dilution of a well-established Kitaev candidate system is realized in the substitutional Ru1x_{1-x}Rhx_xCl3_3 series (x=0.020.6x = 0.02-0.6). Optimized syntheses protocols yield uniformly-doped single crystals and polycrystalline powders that are isostructural to the parental α\alpha-RuCl3_3 as per X-ray diffraction. The Rh content xx is accurately determined by the quantitative energy-dispersive X-ray spectroscopy technique with standards. We determine the magnetic phase diagram of Ru1x_{1-x}Rhx_xCl3_3 for in-plane magnetic fields from magnetization and specific-heat measurements as a function of xx and stacking periodicity, and identify the suppression of the magnetic order at x0.2x \approx 0.2 towards a disordered phase, which does not show any clear signature of freezing into a spin glass. Comparing with previous studies on the substitution series Ru1x_{1-x}Irx_xCl3_3, we propose that chemical pressure would contribute to the suppression of magnetic order especially in Ru1x_{1-x}Irx_xCl3_3 and that the zigzag magnetic ground state appears to be relatively robust with respect to the dilution of the Kitaev--Γ\Gamma--Heisenberg magnetic lattice. We also discovered a slight dependence of the magnetic properties on thermal cycling, which would be due to an incomplete structural transition
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