5,130 research outputs found
Mechanisms for Direct Breakup Reactions
We review some simple mechanisms of breakup in nuclear reactions. We mention
the spectator breakup, which is described in the post-form DWBA. The relation
to other formulations is also indicated. An especially important mechanism is
Coulomb dissociation. It is a distinct advantage that the perturbation due to
the electric field of the nucleus is exactly known. Therefore firm conclusions
can be drawn from such measurements. Some new applications of Coulomb
dissociation for nuclear astrophysics are discussed.Comment: 17 pages, 5 figures, to appear in the proceedings of the RCNP-TMU
Symposium on Spins in Nuclear and Hadronic Reactions, October 16-18 199
An important role for Myb-MuvB and its target gene KIF23 in a mouse model of lung adenocarcinoma
The conserved Myb-MuvB (MMB) multiprotein complex has an important role in transcriptional activation of mitotic genes. MMB target genes are overexpressed in several different cancer types and their elevated expression is associated with an advanced tumor state and a poor prognosis. This suggests that MMB could contribute to tumorigenesis by mediating overexpression of mitotic genes. However, although MMB has been extensively characterized biochemically, the requirement for MMB in tumorigenesis in vivo has not been investigated. Here we demonstrate that MMB is required for tumor formation in a mouse model of lung cancer driven by oncogenic K-RAS. We also identify a requirement for the mitotic kinesin KIF23, a key target gene of MMB, in tumorigenesis. RNA interference-mediated depletion of KIF23 inhibited lung tumor formation in vivo and induced apoptosis in lung cancer cell lines. Our results suggest that inhibition of KIF23 could be a strategy for treatment of lung cancer
Inzicht en toezicht: controle in de kennissamenleving
Nieuwe technieken maken het opslaan en verwerken van informatie eenvoudiger. Sterker\ud
nog: ze maken de weg vrij om gegevens vast te leggen voordat duidelijk is welk inzicht\ud
we eigenlijk nastreven. Toezicht wint zo terrein ten opzichte van de kennisverwerving.\ud
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Voorbeelden van toenemend toezicht zijn elektronische dossiers over burgers,\ud
informatievergaring door de politie en in private initiatieven zoals Google Earth. Deze\ud
systemen maken het mogelijk om op grote schaal verbanden te ontdekken en afwijkingen op\ud
te sporen, zonder dat er duidelijke kennisvragen aan vooraf gaan.\ud
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De relatie tussen inzicht en toezicht is bepalend voor hoe we met de verzamelde kennis\ud
omgaan. Ligt de nadruk daarbij op inzicht, overzicht, toezicht, of nog iets anders? Dit\ud
Jaarboek Kennissamenleving 2010 stelt kritische vragen bij de alomtegenwoordige blik van\ud
toezicht. Het draagt ideeën aan om deze in de toekomst anders te richten, zodat inzicht en\ud
toezicht in balans kunnen blijven
Symmetry energy of dilute warm nuclear matter
The symmetry energy of nuclear matter is a fundamental ingredient in the
investigation of exotic nuclei, heavy-ion collisions and astrophysical
phenomena. New data from heavy-ion collisions can be used to extract the free
symmetry energy and the internal symmetry energy at subsaturation densities and
temperatures below 10 MeV. Conventional theoretical calculations of the
symmetry energy based on mean-field approaches fail to give the correct
low-temperature, low-density limit that is governed by correlations, in
particular by the appearance of bound states. A recently developed quantum
statistical (QS) approach that takes the formation of clusters into account
predicts symmetry energies that are in very good agreement with the
experimental data. A consistent description of the symmetry energy is given
that joins the correct low-density limit with quasiparticle approaches valid
near the saturation density.Comment: 4 pages, 2 figures, 1 tabl
Features of water chemical composition of oligotrophic and eutrophic bogs in the South of the Tomsk region
On the basis of the actual material the analysis of chemical composition of bog waters in the territory of the South of the Tomsk region is carried out. The data on average concentration of macro and trace components, organic matter, pH of bog waters are obtained. Significant distinctions in a chemical composition of surface water for different types of bogs are revealed. The composition and macrostructure of humic acids by the example of eutrophic bogs is studied
Dirac-Brueckner Hartree-Fock Approach: from Infinite Matter to Effective Lagrangians for Finite Systems
One of the open problems in nuclear structure is how to predict properties of
finite nuclei from the knowledge of a bare nucleon-nucleon interaction of the
meson-exchange type. We point out that a promising starting point consists in
Dirac-Brueckner-Hartree-Fock (DBHF) calculations us- ing realistic
nucleon-nucleon interactions like the Bonn potentials, which are able to
reproduce satisfactorily the properties of symmetric nuclear matter without the
need for 3-body forces, as is necessary in non-relativistic BHF calculations.
However, the DBHF formalism is still too com- plicated to be used directly for
finite nuclei. We argue that a possible route is to define effective
Lagrangians with density-dependent nucleon-meson coupling vertices, which can
be used in the Relativistic Hartree (or Relativistic Mean Field (RMF)) or
preferrably in the Relativistic Hartree- Fock (RHF) approach. The
density-dependence is matched to the nuclear matter DBHF results. We review the
present status of nuclear matter DBHF calculations and discuss the various
schemes to construct the self-energy, which lead to differences in the
predictions. We also discuss how effective Lagrangians have been constructed
and are used in actual calculations. We point out that completely consistent
calculations in this scheme still have to be performed.Comment: 16 pages, to be published in Journal of Physics G: Nuclear and
Particle Physics, special issue
Dilution of the magnetic lattice in the Kitaev candidate -RuCl by Rh doping
Magnetic dilution of a well-established Kitaev candidate system is realized
in the substitutional RuRhCl series (). Optimized
syntheses protocols yield uniformly-doped single crystals and polycrystalline
powders that are isostructural to the parental -RuCl as per X-ray
diffraction. The Rh content is accurately determined by the quantitative
energy-dispersive X-ray spectroscopy technique with standards. We determine the
magnetic phase diagram of RuRhCl for in-plane magnetic fields
from magnetization and specific-heat measurements as a function of and
stacking periodicity, and identify the suppression of the magnetic order at towards a disordered phase, which does not show any clear
signature of freezing into a spin glass. Comparing with previous studies on the
substitution series RuIrCl, we propose that chemical pressure
would contribute to the suppression of magnetic order especially in
RuIrCl and that the zigzag magnetic ground state appears to be
relatively robust with respect to the dilution of the
Kitaev----Heisenberg magnetic lattice. We also discovered a slight
dependence of the magnetic properties on thermal cycling, which would be due to
an incomplete structural transition
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