237 research outputs found
Experimental X-ray Stress Analysis Procedures for Ultra High Strength Materials
X-ray stress analysis procedures for accurate measurement of elastic strain in high strength steel
Effect of a patient engagement tool on positive airway pressure adherence: analysis of a German healthcare provider database
Objective/background: This study investigated the addition of a real-time
feedback patient engagement tool on positive airway pressure (PAP) adherence
when added to a proactive telemedicine strategy. Patients/methods: Data from a
German healthcare provider (ResMed Healthcare Germany) were retrospectively
analyzed. Patients who first started PAP therapy between 1 September 2009 and
30 April 2014, and were managed using telemedicine (AirView™; proactive care)
or telemedicine + patient engagement tool (AirView™ + myAir™; patient
engagement) were eligible. Patient demographics, therapy start date, sleep-
disordered breathing indices, device usage hours, and therapy termination rate
were obtained and compared between the two groups. Results: The first 500
patients managed by telemedicine-guided care and a patient engagement tool
were matched with 500 patients managed by telemedicine-guided care only. The
proportion of nights with device usage ≥4 h was 77 ± 25% in the patient
engagement group versus 63 ± 32% in the proactive care group (p < 0.001).
Therapy termination occurred less often in the patient engagement group (p <
0.001). The apnea-hypopnea index was similar in the two groups, but leak was
significantly lower in the patient engagement versus proactive care group (2.7
± 4.0 vs 4.1 ± 5.3 L/min; p < 0.001). Conclusions: Addition of a patient
engagement tool to telemonitoring-guided proactive care was associated with
higher device usage and lower leak. This suggests that addition of an
engagement tool may help improve PAP therapy adherence and reduce mask leak
A high-precision polarimeter
We have built a polarimeter in order to measure the electron beam
polarization in hall C at JLAB. Using a superconducting solenoid to drive the
pure-iron target foil into saturation, and a symmetrical setup to detect the
Moller electrons in coincidence, we achieve an accuracy of <1%. This sets a new
standard for Moller polarimeters.Comment: 17 pages, 9 figures, submitted to N.I.
Adaptive servo-ventilation for central sleep apnea in heart failure
Background Central sleep apnea is associated with poor prognosis and death in patients with heart failure. Adaptive servo-ventilation is a therapy that uses a noninvasive ventilator to treat central sleep apnea by delivering servo-controlled inspiratory pressure support on top of expiratory positive airway pressure. We investigated the effects of adaptive servo-ventilation in patients who had heart failure with reduced ejection fraction and predominantly central sleep apnea. Methods We randomly assigned 1325 patients with a left ventricular ejection fraction of 45% or less, an apnea–hypopnea index (AHI) of 15 or more events (occurrences of apnea or hypopnea) per hour, and a predominance of central events to receive guideline-based medical treatment with adaptive servo-ventilation or guideline-based medical treatment alone (control). The primary end point in the time-to-event analysis was the first event of death from any cause, lifesaving cardiovascular intervention (cardiac transplantation, implantation of a ventricular assist device, resuscitation after sudden cardiac arrest, or appropriate lifesaving shock), or unplanned hospitalization for worsening heart failure. Results In the adaptive servo-ventilation group, the mean AHI at 12 months was 6.6 events per hour. The incidence of the primary end point did not differ significantly between the adaptive servo-ventilation group and the control group (54.1% and 50.8%, respectively; hazard ratio, 1.13; 95% confidence interval [CI], 0.97 to 1.31; P=0.10). All-cause mortality and cardiovascular mortality were significantly higher in the adaptive servo-ventilation group than in the control group (hazard ratio for death from any cause, 1.28; 95% CI, 1.06 to 1.55; P=0.01; and hazard ratio for cardiovascular death, 1.34; 95% CI, 1.09 to 1.65; P=0.006). Conclusions Adaptive servo-ventilation had no significant effect on the primary end point in patients who had heart failure with reduced ejection fraction and predominantly central sleep apnea, but all-cause and cardiovascular mortality were both increased with this therapy. (Funded by ResMed and others; SERVE-HF ClinicalTrials.gov number, NCT00733343. opens in new tab.
Final State Interaction Effects in pol 3He(pol e,e'p)
Asymmetries in quasi-elastic pol 3He(pol e,e'p) have been measured at a
momentum transfer of 0.67 (GeV/c)^2 and are compared to a calculation which
takes into account relativistic kinematics in the final state and a
relativistic one-body current operator. With an exact solution of the Faddeev
equation for the 3He-ground state and an approximate treatment of final state
interactions in the continuum good agreement is found with the experimental
data.Comment: 11 pages, 6 figures, submitted to Phys. Lett. B, revised version,
sensitivity study to relativity and NN-potential adde
Analyzing the impact of different excipients on drug release behavior in hot-melt extrusion formulations using FTIR spectroscopic imaging.
Systematic Evaluation of Nanomaterial Toxicity: Utility of Standardized Materials and Rapid Assays
Measurement of the Electric Form Factor of the Neutron at Q^2=0.5 and 1.0 (GeV/c)^2
The electric form factor of the neutron was determined from measurements of
the \vec{d}(\vec{e},e' n)p reaction for quasielastic kinematics. Polarized
electrons were scattered off a polarized deuterated ammonia target in which the
deuteron polarization was perpendicular to the momentum transfer. The scattered
electrons were detected in a magnetic spectrometer in coincidence with neutrons
in a large solid angle detector. We find G_E^n = 0.0526 +/- 0.0033 (stat) +/-
0.0026 (sys) and 0.0454 +/- 0.0054 +/- 0.0037 at Q^2 = 0.5 and 1.0 (GeV/c)^2,
respectively.Comment: 5 pages, 2 figures, as publishe
The neutron charge form factor and target analyzing powers from 3He(e, e\u27n) scattering
The charge form factor of the neutron has been determined from asymmetries measured in quasi-elastic 3He(e, e\u27n) at a momentum transfer of 0.67 (GeV/c)2. In addition, the target analyzing power, Ayo, has been measured to study effects of final state interactions and meson exchange currents
Functionalized Ag nanoparticles with tunable optical properties for selective protein analysis
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