Healthy Minds: A child and adolescent mental health research project: What are the mental health needs of Bradford's Pakistani Muslim children and young people and how can they be addressed?

This report was commissioned by the City of Bradford Metropolitan District Council (MDC) Directorate of Social Services; the aims and objectives are presented in section two, but simply stated the research seeks to determine the mental health needs of Bradford’s Pakistani Muslim children and young people and, based on the findings, recommend ways in which those needs can be addressed. It is important to mention here that the research was commissioned following a Joint Planning Team recommendation that noted a lack of information around the mental health needs of Bradford’s ‘Asian’ population. A population that makes up a sizeable component of Bradford and yet whose children and young people are significantly under represented in Child & Adolescent Mental Health Services (CAMHS). In recognition of the complexity of cultural, religious, language, geographical regions of origin and socio- economic experience encompassed in the term ‘Asian’ (Patel K, 2000) the decision was taken to concentrate on the Pakistani Muslim community, which is the largest minority ethnic group in Bradford. This introduction will, therefore, through narrative and through a review of the relevant literature, seek to prepare the ground for the views of the professionals, young people, children, parents, carers and community members that follow this chapter. It will paint a broad demographic picture of the UK’s and Bradford’s Pakistani Muslim population; bearing in mind the universal environmental, family and child risk factors as identified by the Health Advisory Service (HAS. 1995) identifying those specific to the Pakistani Muslim population in the Bradford Metropolitan District; and discussing the impact of the findings, negative and positive, on the mental health and mental health needs of the children and young people of this population

Tracking icebergs with time-lapse photography and sparse optical flow, LeConte Bay, Alaska, 2016–2017

We present a workflow to track icebergs in proglacial fjords using oblique time-lapse photos and the Lucas-Kanade optical flow algorithm. We employ the workflow at LeConte Bay, Alaska, where we ran five time-lapse cameras between April 2016 and September 2017, capturing more than 400 000 photos at frame rates of 0.5–4.0 min−1. Hourly to daily average velocity fields in map coordinates illustrate dynamic currents in the bay, with dominant downfjord velocities (exceeding 0.5 m s−1 intermittently) and several eddies. Comparisons with simultaneous Acoustic Doppler Current Profiler (ADCP) measurements yield best agreement for the uppermost ADCP levels (∼ 12 m and above), in line with prevalent small icebergs that trace near-surface currents. Tracking results from multiple cameras compare favorably, although cameras with lower frame rates (0.5 min−1) tend to underestimate high flow speeds. Tests to determine requisite temporal and spatial image resolution confirm the importance of high image frame rates, while spatial resolution is of secondary importance. Application of our procedure to other fjords will be successful if iceberg concentrations are high enough and if the camera frame rates are sufficiently rapid (at least 1 min−1 for conditions similar to LeConte Bay).This work was funded by the U.S. National Science Foundation (OPP-1503910, OPP-1504288, OPP-1504521 and OPP-1504191).Ye

Active Stars in the Spectroscopic Survey of Mid-to-Late M Dwarfs Within 15pc

We present results from the volume-complete spectroscopic survey of 0.1-0.3M$_\odot$ M dwarfs within 15pc. This work discusses the active sample without close binary companions, providing a comprehensive picture of these 123 stars with H${\alpha}$ emission stronger than -1\unicode{xC5}. Our analysis includes rotation periods (including 31 new measurements), H${\alpha}$ equivalent widths, rotational broadening, inclinations, and radial velocities, determined using high-resolution, multi-epoch spectroscopic data from the TRES and CHIRON spectrographs supplemented by photometry from TESS and MEarth. Using this volume-complete sample, we establish that the majority of active, low-mass M dwarfs are very rapid rotators: specifically, 74$\pm$4% have rotation periods shorter than 2 days, while 19$\pm$4% have intermediate rotation periods of 2-20 days, and the remaining 8$\pm$3% have periods longer than 20 days. Among the latter group, we identify a population of stars with very high H${\alpha}$ emission, which we suggest is indicative of dramatic spindown as these stars transition from the rapidly to slowly rotating modes. We are unable to determine rotation periods for six stars and suggest that some of the stars without measured rotation periods may be viewed pole-on, as such stars are absent from the distribution of inclinations we measure; this lack notwithstanding, we recover the expected isotropic distribution of spin axes. Our spectroscopic and photometric data sets also allow us to investigate activity-induced radial-velocity variability, which we show can be estimated as the product of rotational broadening and the photometric amplitude of spot modulation.Comment: Accepted for publication in AJ; 18 pages, 12 figures, 3 table

Proceedings of the Fourth Annual Conference of the MidSouth Computational Biology and Bioinformatics Society

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Designing Authentic Cybersecurity Learning Experiences: Lessons from the Cybermatics Playable Case Study

This paper reports our work on an educational simulation that we call the Playable Case Study (PCS). A PCS is characterized by a fictitious narrative integrated with real-world learning activities, helping students learn skills, knowledge, and dispositions relevant to a professional career. We describe a recent pilot test of a PCS focused on the discipline of cybersecurity, emphasizing the kinds of tensions and difficulties that can arise during the development of immersive, experiential learning experiences: a) challenges accompanying the work of interdisciplinary PCS teams, particularly maintaining technical accuracy while still developing an authentic and engaging narrative; b) reconciling the opportunities provided by the philosophy of the simulation with the need to scaffold educational experiences to support students’ capabilities; and c) integrating the PCS into the classroom environment. We also provide design recommendations, in the form of questions that others can consider if they are attempting to create similar educational experiences

Theory of Experiential Career Exploration Technology (TECET): Increasing cybersecurity career interest through playable case studies

There is a large demand to fill cybersecurity jobs. To alleviate this need, it is important to generate interest in cybersecurity as a career. One way to do this is through job shadowing and internships. Using design science principles, we have built and tested a playable case study (PCS) where participants can act out a virtual internship and learn relevant cybersecurity skills. We ran a study with students in introductory university courses where they played through a simulated internship at a penetration testing company called CyberMatics. In the study we showed that a PCS format helps students 1) better understand what skills and traits are needed for, 2) more firmly decide whether to pursue, and 3) increase their confidence in their ability to succeed in a career in cybersecurity. Through this study we propose the Theory of Experiential Career Exploration Technology (TECET)

Robo-AO M-dwarf Multiplicity Survey: Catalog

We analyze observations from Robo-AO's field M dwarf survey taken on the 2.1 m Kitt Peak telescope and perform a multiplicity comparison with Gaia DR2. Through its laser-guided, automated system, the Robo-AO instrument has yielded the largest adaptive optics M dwarf multiplicity survey to date. After developing an interface to visually identify and locate stellar companions, we selected 11 low-significance Robo-AO detections for follow-up on the Keck II telescope using NIRC2. In the Robo-AO survey we find 553 candidate companions within 4'' around 534 stars out of 5566 unique targets, most of which are new discoveries. Using a position cross-match with DR2 on all targets, we assess the binary recoverability of Gaia DR2 and compare the properties of multiples resolved by both Robo-AO and Gaia. The catalog of nearby M dwarf systems and their basic properties presented here can assist other surveys which observe these stars, such as the NASA TESS mission

Resistance Mutations to Zidovudine and Saquinavir in Patients Receiving Zidovudine plus Saquinavir or Zidovudine and Zalcitabine plus Saquinavir in AIDS Clinical Trials Group 229

The relationships among treatment regimens, plasma human immunodeficiency virus (HIV) RNA levels, and resistance mutations to saquinavir (codons 48 and 90) and zidovudine (codon 215) were examined in a cohort of 144 patients from the AIDS Clinical Trials Group 229 study. After 24-40 weeks of therapy, no patients who had received the two-drug combination (zidovudine plus saquinavir) had only codon 48 mutations, 45.8% had only codon 90 mutations, and 8.3% had both codon 48 and 90 mutations. Mutations developed by patients who had received the three-drug combination (zidovudine and zalcitabine plus saquinavir) were codon 48 alone in 1.4%, codon 90 alone in 33.3%, and both codons 48 and 90 in 4.2%. The difference between the groups showed a trend toward reduced mutations with three versus two drugs but did not reach significance (p = .11, two-sided χ2). Higher baseline HIV RNA levels correlated with the development of protease mutations. Mutations at codon 215 were present in 82% of all patients at baseline and in 87% after therap

Coronary angiographic morphology in myocardial infarction: A link between the pathogenesis of unstable angina and myocardial infarction

It has previously been shown that analysis of coronary morphology can separate unstable from stable angina. An eccentric stenosis with a narrow neck or irregular borders, or both, is very common in patients who present with acute unstable angina, whereas it is rare in patients with stable angina. To extend these observations to myocardial infarction, the coronary morphology of 41 patients with acute or recent infarction and nontotally occluded infarct vessels was studied. For all patients, 27 (66%) of 41 infarct vessels contained this eccentric narrowing, whereas only 2 (11%) of 18 noninfarct vessels with narrowing of 50 to less than 100% had this lesion (p < 0.001). In addition, a separate group of patients with acute myocardial infarction who underwent intracoronary streptokinase infusion were also analyzed in similar fashion. Fourteen (61%) of 23 infarct vessels contained this lesion after streptokinase infusion compared with 1 (9%) of 11 noninfarct vessels with narrowing of 50 to less than 100% (p < 0.01).Therefore, an eccentric coronary stenosis with a narrow neck or irregular borders, or both, is the most common morphologic feature on angiography in both acute and recent infarction as well as unstable angina. This lesion probably represents either a disrupted atherosclerotic plaque or a partially occlusive or lysed thrombus, or both. The predominance of this morphology in both unstable angina and acute infarction suggests a possible link between these two conditions. Unstable angina and myocardial infarction may form a continuous spectrum with the clinical outcome dependent on the subsequent change in coronary supply relative to myocardial demand