56 research outputs found
Évolution des comportements et des représentations sociales liés à la consommation de cannabis chez les adolescents. Résumé
La recherche, dont les résultats principaux sont
décrits dans ce résumé, visait trois objectifs différents:
a) mieux comprendre l'évolution de la
consommation de substances durant l'adolescence;
b) mesurer les représentations sociales, par
rapport à la consommation, dans une population
de consommateurs comparée à une population
«tout-venant»; c) valider un instrument de dépistage
de la consommation.
L'échantillon, sur lequel porte l'observation du
suivi, est représentatif d'une population de
consommateurs de substances. Le suivi a été
réalisé sur une période de quatre ans, l'âge des
sujets variant entre 15 et 20 ans au moment du
premier entretien. Pour l'évaluation des représentations
sociales, une population «tout-venant» a
été recrutée, afin de pouvoir comparer les attitudes
et opinions des adolescents en relation avec
la consommation. Enfin, pour la validation de
l'instrument de screening, les deux populations,
suivi et «tout-venant», ont été réunies
Assertive outreach treatment versus care as usual for the treatment of high-need, high-cost alcohol related frequent attenders: study protocol for a randomised controlled trial
Background: Alcohol-related hospital admissions have doubled in the last ten years to >1.2m per year in England. High-need, high-cost (HNHC) alcohol-related frequent attenders (ARFA) are a relatively small subgroup of patients, having multiple admissions or attendances from alcohol during a short time period. This trial aims to test the effectiveness of an assertive outreach treatment (AOT) approach in improving clinical outcomes for ARFA, and reducing resource use in the acute setting.
Methods: One hundred and sixty ARFA patients will be recruited and following baseline assessment, randomly assigned to AOT plus care as usual (CAU) or CAU alone in equal numbers. Baseline assessment includes alcohol consumption and related problems, physical and mental health comorbidity and health and social care service use in the previous 6 months using standard validated tools, plus a measure of resource use. Follow-up assessments at 6 and 12months after randomization includes the same tools as baseline plus standard measure of patient satisfaction. Outcomes for CAU+AOT and CAU at 6 and 12months will be compared, controlling for pre-specified baseline measures. Primary outcome will be percentage of days abstinent at 12months. Secondary outcomes include emergency department (ED) attendance, number and length of hospital admissions, alcohol consumption, alcohol-related problems, other health service use, mental and physical comorbidity 6 and 12months post intervention. Health economic analysis will estimate the economic impact of AOT from health, social care and societal perspectives and explore cost-effectiveness in terms of quality adjusted life years and alcohol consumption at 12-month follow-up.
Discussion: AOT models piloted with alcohol dependent patients have demonstrated significant reductions in alcohol consumption and use of unplanned National Health Service (NHS) care, with increased engagement with alcohol treatment services, compared with patients receiving CAU. While AOT interventions are costlier per case than current standard care in the UK, the rationale for targeting HNHC ARFAs is because of their disproportionate contribution to overall alcohol burden on the NHS. No previous studies have evaluated the clinical and costeffectiveness of AOT for HNHC ARFAs: this randomized controlled trial (RCT) targeting ARFAs across five South London NHS Trusts is the first. Trial registration: International standard randomized controlled trial number (ISRCTN) registry: ISRCTN67000214, retrospectively registered 26/11/2016
A multimodal approach for tracing lateralization along the olfactory pathway in the honeybee through electrophysiological recordings, morpho-functional imaging, and behavioural studies
Recent studies have revealed asymmetries between the left and right sides of
the brain in invertebrate species. Here we present a review of a series of
recent studies from our labs, aimed at tracing asymmetries at different stages
along the honeybee's (Apis mellifera) olfactory pathway. These include
estimates of the number of sensilla present on the two antennae, obtained by
scanning electron microscopy, as well as electroantennography recordings of the
left and right antennal responses to odorants. We describe investigative
studies of the antennal lobes, where multi-photon microscopy is used to search
for possible morphological asymmetries between the two brain sides. Moreover,
we report on recently published results obtained by two-photon calcium imaging
for functional mapping of the antennal lobe aimed at comparing patterns of
activity evoked by different odours. Finally, possible links to the results of
behavioural tests, measuring asymmetries in single-sided olfactory memory
recall, are discussed.Comment: 28 pages, 8 figure
Greek Music and Poetry - Hermann Koller: Musik und Dichtung im alten Griechenland. Pp. 212; 20 plates. Bern: Francke, 1963. Cloth, 24.50 Sw. fr.
(Alister) Cameron The identity of Oedipus the king: five essays on the Oedipus Tyrannus. New York: New York University Press (London: University of London Press). 1968. Pp. xxiii + 165. $6.95.
Der griechische Rhythmus: Musik, Reigen, Vers und Sprache. By T. Georgiades. Pp. 163. Hamburg: Marion von Schröder, 1949.
Greek Music - Otto Johannes Gombosi: Tonarten und Stimmungen der antiken Musik. Pp. xiii+148; 1 plate. Copenhagen: Munksgaard, 1939 [1950]. Paper, kr. 25.
The Loeb Aeschylus - Aeschylus. With an English translation by Herbert Weir Smyth. Vol. ii. Reprinted with an Appendix edited by Hugh Lloyd-Jones. (Loeb Classical Library.) Pp. 611. London: Heinemann, 1957. Cloth, 15 s
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