Bad apples in bad barrels revisited: Cognitive moral development, just world beliefs, rewards, and ethical decision-making

In this study, we test the interactive effect on ethical decision-making of (1) personal characteristics, and (2) personal expectancies based on perceptions of organizational rewards and punishments. Personal characteristics studied were cognitive moral development and belief in a just world. Using an in-basket simulation, we found that exposure to reward system information influenced managers' outcome expectancies. Further, outcome expectancies and belief in a just world interacted with managers' cognitive moral development to influence managers' ethical decision-making. In particular, low-cognitive moral development managers who expected that their organization condoned unethical behavior made less ethical decisions while high cognitive moral development managers became more ethical in this environment. Low cognitive moral development managers also behaved less ethically when their belief in a just world was high

Effects of Tropical Storm Agnes on Nutrient Flux and Distribution in Lower Chesapeake Bay

Nutrient concentrations measured in lower Chesapeake Bay in the summer of 1972 immediately following the flooding associated with Tropical Storm Agnes are compared with those in the summer of 1973, a season of more normal rainfall. The large amount of land runoff produced unseasonably high concentrations of dissolved inorganic nitrogen in the Bay near the mouth of the Potomac River. Phosphate concentrations were essentially unaffected by the flooding. Fluxes of total nitrogen and total phosphorus nutrients through the mouth of Chesapeake Bay were calculated for both summers. The calculated net export of nutrients from the Bay in both August 1972, and June 1973 was found to be small in comparison to nutrient inputs.https://scholarworks.wm.edu/vimsbooks/1068/thumbnail.jp

Physicochemical and biological properties of novel chlorhexidine‐loaded nanotube‐modified dentin adhesive

A commercially available three‐step (etch‐and‐rinse) adhesive was modified by adding chlorhexidine (CHX)‐loaded nanotubes (Halloysite®, HNT) at two concentrations (CHX10% and CHX20%). The experimental groups were: SBMP (unmodified adhesive, control), HNT (SBMP modified with HNT), CHX10 (SBMP modified with HNT loaded with CHX10%), and CHX20 (SBMP modified with HNT loaded with CHX20%). Changes in the degree of conversion (DC%), Knoop hardness (KHN), water sorption (WS), solubility (SL), antimicrobial activity, cytotoxicity, and anti‐matrix metalloproteinase [MMP‐1] activity (collagenase‐I) were evaluated. In regards to DC%, two‐way ANOVA followed by Tukey’s post‐hoc test revealed that only the factor “adhesive” was statistically significant (p 0.05). For Knoop microhardness, one‐way ANOVA followed by the Tukey’s test showed statistically significant differences when comparing HNT (20.82 ± 1.65) and CHX20% (21.71 ± 2.83) with the SBMP and CHX10% groups. All adhesives presented similar WS and cytocompatibility. The CHX‐loaded nanotube‐modified adhesive released enough CHX to inhibit the growth of S. mutans and L. casei. Adhesive eluates were not able to effectively inhibit MMP‐1 activity. The evaluation of higher CHX concentrations might be necessary to provide an effective and predictable MMP inhibition. © 2018 Wiley Periodicals, Inc. J Biomed Mater Res B Part B, 2018. © 2018 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater 107B: 868–875, 2019.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/148225/1/jbmb34183_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/148225/2/jbmb34183.pd

Psychological adaptation and recovery in youth with sarcoma: a qualitative study with practical implications for clinical care and research

Objectives: This study explored factors that play a role in psychological adaptation and recovery of young people with sarcoma. / Design: Qualitative study. / Setting: National Health Service hospitals in the UK. / Methods: Using purposive sampling, participants were recruited for semistructured interviews over the telephone or face to face in order to answer questions about how cancer impacted various domains of their life. Data were analysed using a framework approach. / Results: Thirty participants, aged 15–39 years with primary sarcoma diagnosis provided in-depth accounts of their experience. Emerging themes from the interviews were grouped into two overarching themes that relate to one’s adaptation to illness: individual level and environmental level. The qualitative nature of our study sheds light on meaningful connections between various factors and their role in one’s psychological adaptation to sarcoma. We devised a visual matrix to illustrate how risk and protective factors in adaptation vary between and within individuals. / Conclusions: This study demonstrates that young people with sarcoma report an array of both positive and negative factors related to their illness experience. The route to recovery is a multifactorial process and a one-size-fits-all approach to psychosocial care proves inadequate. We propose that moving beyond the latent constructs of resilience and psychopathology towards a dynamic model of psychological adaptation and recovery in this population can result in optimisation of care. We offer some recommendations for professionals working with young people with sarcoma in clinic and research

Electron-phonon coupling in the conventional superconductor YNi2_2B2_2C at high phonon energies studied by time-of-flight neutron spectroscopy

We report an inelastic neutron scattering investigation of phonons with energies up to 159 meV in the conventional superconductor YNi$_2$B$_2$C. Using the SWEEP mode, a newly developed time-of-flight technique involving the continuous rotation of a single crystal specimen, allowed us to measure a four dimensional volume in (Q,E) space and, thus, determine the dispersion surface and linewidths of the $A_{1g}$ (~ 102 meV) and $A_u$ (~ 159 meV) type phonon modes for the whole Brillouin zone. Despite of having linewidths of $\Gamma = 10 meV$, $A_{1g}$ modes do not strongly contribute to the total electron-phonon coupling constant $\lambda$. However, experimental linewidths show a remarkable agreement with ab-initio calculations over the complete phonon energy range demonstrating the accuracy of such calculations in a rare comparison to a comprehensive experimental data set.Comment: accepted for publication in PR

Doxycycline-loaded nanotube-modified adhesives inhibit MMP in a dose-dependent fashion

OBJECTIVES: This article evaluated the drug loading, release kinetics, and matrix metalloproteinase (MMP) inhibition of doxycycline (DOX) released from DOX-loaded nanotube-modified adhesives. DOX was chosen as the model drug, since it is the only MMP inhibitor approved by the U.S. Food and Drug Administration. MATERIALS AND METHODS: Drug loading into the nanotubes was accomplished using DOX solution at distinct concentrations. Increased concentrations of DOX significantly improved the amount of loaded DOX. The modified adhesives were fabricated by incorporating DOX-loaded nanotubes into the adhesive resin of a commercial product. The degree of conversion (DC), Knoop microhardness, DOX release kinetics, antimicrobial, cytocompatibility, and anti-MMP activity of the modified adhesives were investigated. RESULTS: Incorporation of DOX-loaded nanotubes did not compromise DC, Knoop microhardness, or cell compatibility. Higher concentrations of DOX led to an increase in DOX release in a concentration-dependent manner from the modified adhesives. DOX released from the modified adhesives did not inhibit the growth of caries-related bacteria, but more importantly, it did inhibit MMP-1 activity. CONCLUSIONS: The loading of DOX into the nanotube-modified adhesives did not compromise the physicochemical properties of the adhesives and the released levels of DOX were able to inhibit MMP activity without cytotoxicity. CLINICAL SIGNIFICANCE: Doxycycline released from the nanotube-modified adhesives inhibited MMP activity in a concentration-dependent fashion. Therefore, the proposed nanotube-modified adhesive may hold clinical potential as a strategy to preserve resin/dentin bond stability

Multiple magnetic ordering phenomena in multiferroic o-HoMnO3

Orthorhombic HoMnO3 is a multiferroic in which Mn antiferromagnetic order induces ferroelectricity. A second transition occurs within the multiferroic phase, in which a strong enhancement of the ferroelectric polarization occurs concomitantly to antiferromagnetic ordering of Ho 4f magnetic moments. Using the element selectivity of resonant X-ray diffraction, we study the magnetic order of the Mn 3d and Ho 4f moments. We explicitly show that the Mn magnetic order is affected by the Ho 4f magnetic ordering transition. Based on the azimuthal dependence of the (0 q 0) and (0 1-q 0) magnetic reflections, we suggest that the Ho 4f order is similar to that previously observed for Tb 4f in TbMnO3, which resembles an ac-cycloid. This is unlike the Mn order, which has already been shown to be different for the two materials. Using non-resonant diffraction, we show that the magnetically-induced ferroelectric lattice distortion is unaffected by the Ho ordering, suggesting a mechanism through which the Ho order affects polarization without affecting the lattice in the same manner as the Mn order