419 research outputs found

    A Call for Item-ordering Transparency in Online IS Survey Administration

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    Online survey applications typically offer the capability to individually randomize the order in which survey items are presented to subjects, a method that structurally eliminates several sources of method bias inherent to static surveys. IS researchers who use online surveys have a strong interest in knowing how prior surveys were administered in published research, however, we find this information is rarely available in current practice. This paper presents a call for increased transparency in reporting item-ordering methodology in future online IS survey research. This call is based on 1) a literature review of online survey research published in the AIS Senior Scholars’ Basket of Journals, 2) results of new research comparing reliability and construct validity characteristics produced by individually-randomized vs. static survey administration methods, and 3) results of hypothetical structural equation modeling (SEM) analyses contrasting structural models following purification of the individually-randomized and static datasets

    Activity Predicts Male Reproductive Success in a Polygynous Lizard

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    Activity patterns and social interactions play a key role in determining reproductive success, although this is poorly understood for species that lack overt social behaviour. We used genetic paternity analysis to quantify both multiple paternity and the relative roles of activity and social behaviour in determining reproductive success in a nondescript Australian lizard. During the breeding season we intensively followed and recorded the behaviour of a group of seven males and 13 females in a naturalistic outdoor enclosure to examine the relative roles of body size, activity and social interactions in determining male fertilization success. We found multiple paternity in 42% of clutches. No single behaviour was a significant predictor of male fertilization success in isolation, but male-female association, interactions and courtship explained 41% of the variation in male fertilization success. Males with the highest number of offspring sired invested heavily in interacting with females but spent very little time in interactions with males. These same males also sired offspring from more clutches. When taken collectively, an index of overall male activity, including locomotion and all social interactions, significantly explained 81% of the variation in the total number of offspring sired and 90% of the variation in the number of clutches in which males sired offspring. We suggest that the most successful male strategy is a form of endurance rivalry in which active mate searching and interactions with females have the greatest fitness benefits.This work was supported by grants from the Australian Research Council to JSK

    The Iowa Homemaker vol.3, no.3-4

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    Table of Contents The Architectural Design of a Home by Allen Holmes Kimball, page 1 “For a Man’s House Is His Castle” by Alda Wilson, page 2 The Economics of Consumption compiled by John E. Brindley, page 3 Sunfast and Tubfast Materials by Pearl Apland, page 5 On Our Street by Juanita J. Beard, page 6 Who Is Responsible for the Child? by Orange H. Cessna, page 7 Summer Suppers by N. Beth Bailey, page 8 Vacation First Aid by Dr. Mary Sheldon, page 9 Episodes Concerning Evolution of Home Economics by Ruth Elaine Wilson, page 10 Extravagant Economics by Blanche Ingersoll, page 11 Breakfast Bridge by Eleanor Murray, page 12 Veishea Celebrates First Birthday by Helen G. Lamb, page 1

    Anticipatory prescribing in end-of-life care

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    Anticipatory prescriptions are often issued by GPs for patients nearing the end of life, ahead of symptoms they may experience. These prescriptions are often activated by nurses. This article summarises a study investigating nurses’ experiences of using anticipatory prescriptions

    The acute transcriptome response of the midbrain/diencephalon to injury in the adult mummichog (\u3cem\u3eFundulus heteroclitus\u3c/em\u3e)

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    Adult fish produce new cells throughout their central nervous system during the course of their lives and maintain a tremendous capacity to repair damaged neural tissue. Much of the focus on understanding brain repair and regeneration in adult fish has been directed at regions of the brainstem and forebrain; however, the mesencephalon (midbrain) and diencephalon have received little attention. We sought to examine differential gene expression in the midbrain/diencephalon in response to injury in the adult fish using RNA-seq. Using the mummichog (Fundulus heteroclitus), we administered a mechanical lesion to the midbrain/diencephalon and examined differentially expressed genes (DEGs) at an acute recovery time of 1 h post-injury. Comparisons of whole transcriptomes derived from isolated RNA of intact and injured midbrain/diencephalic tissue identified 404 DEGs with the vast majority being upregulated. Using qPCR, we validated the upregulation of DEGs pim-2-like, syndecan-4-like, and cd83. Based on genes both familiar and novel regarding the adult brain response to injury, these data provide an extensive molecular profile giving insight into a range of cellular processes involved in the injury response of a brain regenerative-capable vertebrate

    The acute transcriptome response of the midbrain/diencephalon to injury in the adult mummichog (\u3cem\u3eFundulus heteroclitus\u3c/em\u3e)

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    Adult fish produce new cells throughout their central nervous system during the course of their lives and maintain a tremendous capacity to repair damaged neural tissue. Much of the focus on understanding brain repair and regeneration in adult fish has been directed at regions of the brainstem and forebrain; however, the mesencephalon (midbrain) and diencephalon have received little attention. We sought to examine differential gene expression in the midbrain/diencephalon in response to injury in the adult fish using RNA-seq. Using the mummichog (Fundulus heteroclitus), we administered a mechanical lesion to the midbrain/diencephalon and examined differentially expressed genes (DEGs) at an acute recovery time of 1 h post-injury. Comparisons of whole transcriptomes derived from isolated RNA of intact and injured midbrain/diencephalic tissue identified 404 DEGs with the vast majority being upregulated. Using qPCR, we validated the upregulation of DEGs pim-2-like, syndecan-4-like, and cd83. Based on genes both familiar and novel regarding the adult brain response to injury, these data provide an extensive molecular profile giving insight into a range of cellular processes involved in the injury response of a brain regenerative-capable vertebrate

    The Iowa Homemaker vol.2, no.5-6

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    Table of Contents Your Child Between the Bottle and School Age by Belle Lowe, page 1 Buy Your Hat From Your Grocery Savings by Blanche Ingersoll, page 2 Has Hosiery Become Your Hobby? by Mildred B. Elder, page 3 Pottery Making as a Community Work by Paul E. Cox, page 4 Fall Forecast for Children’s Frocks by Helen Paschal, page 5 “Ye Hatte Shoppe” As a Summer’s Occupation by Ruth Wilson, page 6 Will Courtesy Count in Your Child’s Career? by Eda Lord Murphy, page 7 Who’s There and Where by Jeanette Beyer, page 10 Card File Your Foreign Terms by Eleanor Murphy, page 10 Rival the Orient With Sealing Wax by Opal Wind, page 11 “Back to Natur”-ing With a Camp Kit by Helen T. Peterson, page 12 The Art of Outcasting Flies by Dorothy Morris, page 1

    Redox-switchable siderophore anchor enables reversible artificial metalloenzyme assembly

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    Artificial metalloenzymes that contain protein-anchored synthetic catalysts are attracting increasing interest. An exciting, but still unrealized advantage of non-covalent anchoring is its potential for reversibility and thus component recycling. Here we present a siderophore–protein combination that enables strong but redox-reversible catalyst anchoring, as exemplified by an artificial transfer hydrogenase (ATHase). By linking the iron(iii)-binding siderophore azotochelin to an iridium-containing imine-reduction catalyst that produces racemic product in the absence of the protein CeuE, but a reproducible enantiomeric excess if protein bound, the assembly and reductively triggered disassembly of the ATHase was achieved. The crystal structure of the ATHase identified the residues involved in high-affinity binding and enantioselectivity. While in the presence of iron(iii), the azotochelin-based anchor binds CeuE with high affinity, and the reduction of the coordinated iron(iii) to iron(ii) triggers its dissociation from the protein. Thus, the assembly of the artificial enzyme can be controlled via the iron oxidation state

    Bridging Alone: Religious Conservatism, Marital Homogamy, and Voluntary Association Membership

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    This study characterizes social insularity of religiously conservative American married couples by examining patterns of voluntary associationmembership. Constructing a dataset of 3938 marital dyads from the second wave of the National Survey of Families and Households, the author investigates whether conservative religious homogamy encourages membership in religious voluntary groups and discourages membership in secular voluntary groups. Results indicate that couples’ shared affiliation with conservative denominations, paired with beliefs in biblical authority and inerrancy, increases the likelihood of religious group membership for husbands and wives and reduces the likelihood of secular group membership for wives, but not for husbands. The social insularity of conservative religious groups appears to be reinforced by homogamy—particularly by wives who share faith with husbands
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