262 research outputs found

    Service: Meeting Youth\u27s Need To Be Needed

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    In April 1861, hours after the smoke cleared at Fort Sumpter, the first volunteer military units from the North were organized in preparation for the battle to preserve the Union. They were from Minnesota. The North Star State is again mobilizing, capturing some of the fresh air of the service movement sweeping the nation, and adding its own populist brand of citizen involvement. Youth service is blooming in America\u27s heartland, and community educators are leading the way

    Effects of Estuary-Wide Seagrass Loss on Fish Populations

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    Globally, habitat loss in coastal marine systems is a major driver of species decline, and estuaries are particularly susceptible to loss. Along the United States Pacific coast, monospecific eelgrass (Zostera marina) beds form the major estuarine vegetated habitat. In Morro Bay, California, eelgrass experienced an unprecedented decline of \u3e 95%, from 139 ha in 2007 to \u3c 6 ha by 2017. Fish populations were compared before and after the eelgrass decline using trawl surveys. Beach seines surveys were also conducted during the post-decline period to characterize species within and outside of remnant eelgrass beds.While the estuary-wide loss of eelgrass did not result in fewer fish or less biomass, it led to changes in species composition. The post-eelgrass decline period was characterized by increases in flatfish (mainly Citharichthys stigmaeus) and staghorn sculpin (Leptocottus armatus), and decreases in habitat specialists including bay pipefish (Syngnathus leptorhynchus) and shiner perch (Cymatogaster aggregata). There were similar trends inside and outside of remnant eelgrass patches. These findings support evidence across multiple ecosystems suggesting that the predominance of habitat-specialists predicts whether or not habitat loss leads to an overall decline in fish abundance. In addition, loss of critical habitats across seascapes can restrict population connectivity and lead to range contraction. For bay pipefish, the loss of eelgrass in Morro Bay is likely to create a population biogeographic divide. Currently, Morro Bay is dominated by flatfish and sculpins, and the longevity of this new ecosystem state will depend on future eelgrass recovery dynamics supported by ecosystem-based management approaches

    EXOGEN ultrasound bone healing system for long bone fractures with non-union or delayed healing: a NICE medical technology guidance

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    Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.This article has been made available through the Brunel Open Access Publishing Fund.A routine part of the process for developing National Institute for Health and Care Excellence (NICE) medical technologies guidance is a submission of clinical and economic evidence by the technology manufacturer. The Birmingham and Brunel Consortium External Assessment Centre (EAC; a consortium of the University of Birmingham and Brunel University) independently appraised the submission on the EXOGEN bone healing system for long bone fractures with non-union or delayed healing. This article is an overview of the original evidence submitted, the EAC’s findings, and the final NICE guidance issued.The Birmingham and Brunel Consortium is funded by NICE to act as an External Assessment Centre for the Medical Technologies Evaluation Programme

    Dmitri Bovykine, Î‘ĐœĐ°Ń‚ĐŸĐ»ĐžĐč Î’Đ°ŃĐžĐ»ŃŒĐ”ĐČоч Î‘ĐŽĐŸâ€Ż: ĐŸĐ±Ń€Đ°Đ· ĐżĐ°ĐŒŃŃ‚ŃŒ [Anatoli Vassilievitch Ado : image et mĂ©moire]

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    Les historiens sont prisonniers de leur temps : le regard qu’ils portent sur le passĂ© est dĂ©terminĂ© par leur prĂ©sent et les rĂ©sultats de leurs travaux sont sans cesse remis en question et dĂ©passĂ©s. Anatoli Vassilievitch Ado n’échappe pas Ă  ce piĂšge tendu par le temps Ă  la scientificitĂ© de l’histoire. NĂ© le 8 janvier 1928 et mort le 1er juillet 1995, il a vĂ©cu et ƓuvrĂ© en URSS sous l’emprise de l’idĂ©ologie dominante. Sa formation Ă  l’UniversitĂ© de Moscou (1945‑1953) ainsi que l’enseignement qu..

    Efficacy of salmeterol/fluticasone propionate by GOLD stage of chronic obstructive pulmonary disease: analysis from the randomised, placebo-controlled TORCH study

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    Background: The efficacy of inhaled salmeterol plus fluticasone propionate (SFC) in patients with severe or very severe COPD is well documented. However, there are only limited data about the influence of GOLD severity staging on the effectiveness of SFC, particularly in patients with milder disease. Methods: TORCH was a 3-year, double-blind, placebo-controlled trial of 6112 patients with moderate/severe COPD with pre-bronchodilator FEV1 < 60% predicted (mean age 65 years, 76% male, mean 44% predicted FEV1, 43% current smokers). To understand the relative efficacy of SFC and its components by GOLD stages, we conducted a post-hoc analysis of the TORCH dataset using baseline post-bronchodilator FEV1 to segment patients into three groups: moderate COPD (GOLD stage II and above: Âł 50%; n = 2156), severe COPD (GOLD stage III: 30% to < 50%; n = 3019) and very severe COPD (GOLD stage IV: < 30%; n = 937). Results: Compared with placebo, SFC improved post-bronchodilator FEV1: 101 ml (95% confidence interval [CI]: 71, 132) in GOLD stage II, 82 ml (95% CI: 60, 104) in GOLD stage III and 96 ml (95% CI: 54, 138) in GOLD stage IV patients, and reduced the rate of exacerbations: 31% (95% CI: 19, 40) in GOLD stage II, 26% (95% CI: 17, 34) in GOLD stage III and 14% (95% CI: -4,29) in GOLD stage IV. SFC improved health status to a greater extent than other treatments regardless of baseline GOLD stage. Similarly, SFC reduced the risk of death by 33% (hazard ratio [HR] 0.67; 95% CI: 0.45, 0.98) for GOLD stage II, 5% (HR 0.95; 95% CI: 0.73, 1.24) for GOLD stage III, and 30% (HR 0.70; 95% CI: 0.47, 1.05) for GOLD stage IV. The rates of adverse events were similar across treatment arms and increased with disease severity. Overall, there was a higher incidence of pneumonia in the fluticasone propionate and SFC arms, compared with other treatments in all GOLD stages. Conclusion: In the TORCH study, SFC reduced moderate-to-severe exacerbations and improved health status and FEV1 across GOLD stages. Treatment with SFC may be associated with reduced mortality compared with placebo in patients with GOLD stage II disease. The effects were similar to those reported for the study as a whole. Thus, SFC is an effective treatment option for patients with GOLD stage II COPD

    Tracer diffusion in granular shear flows

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    Tracer diffusion in a granular gas in simple shear flow is analyzed. The analysis is made from a perturbation solution of the Boltzmann kinetic equation through first order in the gradient of the mole fraction of tracer particles. The reference state (zeroth-order approximation) corresponds to a Sonine solution of the Boltzmann equation, which holds for arbitrary values of the restitution coefficients. Due to the anisotropy induced in the system by the shear flow, the mass flux defines a diffusion tensor DijD_{ij} instead of a scalar diffusion coefficient. The elements of this tensor are given in terms of the restitution coefficients and mass and size ratios. The dependence of the diffusion tensor on the parameters of the problem is illustrated in the three-dimensional case. The results show that the influence of dissipation on the elements DijD_{ij} is in general quite important, even for moderate values of the restitution coefficients. In the case of self-diffusion (mechanically equivalent particles), the trends observed in recent molecular dynamics simulations are similar to those obtained here from the Boltzmann kinetic theory.Comment: 5 figure

    Local inequality and crime: exploring how variation in the scale of the inequality measures affects relationships betweeen inequality and crime

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    There is considerable interest in the role of inequality in affecting social outcomes yet there is also uncertainty and disagreement about the appropriate scale at which to measure inequality within such analyses. Whilst some have argued for larger-area inequality measures to be used there are good theoretical, empirical and intuitive grounds to think that local inequality may have relevance as a driver of social ills. This paper explores whether differing understandings of ‘local’ inequality does—or can—matter and, if so, within which contexts this is the case. Contrasting findings across the two areas support the notion that local inequality does have relevance to social outcomes but that the socio-spatial context matters
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