Comment on: The Vitamin D⁻Folate Hypothesis as an Evolutionary Model for Skin Pigmentation: An Update and Integration of Current Ideas, Nutrients 2018, 10, 554.

In response to a recent article by Jones et al. (Nutrients 10: 554⁻568, 2018) [1], we agree that three distinctive features evolved in Homo erectus prior to the emergence of modern humans.[...]

A Lesson Before Prying: Invitation to Inquiry within a Collaborative Community of Literacy Educators

A university-school collaborative, responding to the many challenges of urban educators, including high-stakes testing, invited the authors to improve literacy instruction. The authors chronicle their initials steps of this action research. Their lesson before prying into the teaching and learning lives of the stakeholders of the learning community indicated that the teachers a) used professional vocabulary that often conflicted with classroom practices, b) expressed interest in improving instruction, and c) highly value their students

SB 201 - Sick Leave

The Act amends Georgia’s general provisions relating to labor and industrial relations by adding a new provision that requires qualifying employers to allow their employees to use sick leave to care for immediate family members

Restoring the Chesapeake--A Watershed Education and Restoration Project for Virginia Youth

A watershed education and restoration project was started in the Virginia portion of the Chesapeake Bay watershed in 2002. Over 37,000 hardwood seedlings were distributed to school groups and 4-H leaders in 19 counties. A geographic information system (GIS) identified subwatersheds in greatest need of riparian restoration. A Web site provided educational material and facilitated communication. Results indicate 3 years are needed to develop partnerships necessary for large-scale projects such as this one. Hands-on activities like planting trees result in large knowledge gains. Use of land-use maps and a Web site also result in knowledge gain about watershed

The development of norms of pediatric interpupillary distance

Interpupillary distances (PDs) were measured on 220 Caucasian children, newborn to six years of age, at fixation distances of 3 m and 40 em. A photographic method was used to determine the distance between the corneal light reflexes provided by the camera flash. The subjects were divided into six groups based on age. The average PDs (mm) for each age group were: Group 1 (newborn-11 months): NA/40.5; Group 2 (12-23 months): 46.5/43.0; Group 3 (24-35 months): 47.5/43.5; Group 4 (36-47 months): 49.5/46.0; Group 5 (48-59 months): 51.0/46.5; Group 6 (60-71 months): 51.0/46.5; far/near respectively

Functional Reprogramming of the Primary Immune Response by T Cell Receptor Antagonism

The T cell receptor must translate modest, quantitative differences in ligand binding kinetics into the qualitatively distinct signals used to determine cell fate. Here, we use mice that express an endogenous T cell receptor (TCR) antagonist and an adoptive transfer system to examine the influence of TCR signal quality on the development of effector function. We show that activation of antigen-specific T cells in the presence of an antagonist results in a functional reprogramming of the primary immune response, marked by altered T cell homing, a failure to develop effector function, and ultimately clonal elimination by apoptosis. Importantly, antagonism does not block cell division, implying that the signals promoting clonal expansion and effector differentiation are distinct

Maximizing Access through Consortial Partnership: Mississippi State Univeristy Libraries\u27 Journal Expansion Project

Consortial licenses with online access clauses can offer libraries the opportunity to begin new journal subscriptions at no additional cost and without losing access to existing subscriptions. Mississippi State University (MSU) participates in consortial partnerships that provide online access to all Elsevier and Wiley journals to which any partner subscribes. The license agreements prohibit simply canceling duplicate subscriptions, but allow any library to swap existing subscriptions for titles of equal cost. In 2006, librarians realized MSU was paying for access that it would retain regardless of whether it maintained subscriptions because many subscriptions were duplicated with partner libraries. This article describes a project that allowed MSU to provide online access to an additional 60 journals at no additional cost

Maximizing Access through Consortial Partnership: Mississippi State University Libraries’ Journal Expansion Project

The published article may contain minor edits and revisions not included in this preprint.Consortial licenses with online access clauses can offer libraries the opportunity to begin new journal subscriptions at no additional cost and without losing access to existing subscriptions. Mississippi State University (MSU) participates in consortial partnerships that provide online access to all Elsevier and Wiley journals to which any partner subscribes. The license agreements prohibit simply canceling duplicate subscriptions, but allow any library to swap existing subscriptions for titles of equal cost. In 2006, librarians realized MSU was paying for access that it would retain regardless of whether it maintained subscriptions because many subscriptions were duplicated with partner libraries. This article describes a project that allowed MSU to provide online access to an additional 60 journals at no additional cost

Adenosine and Stroke: Maximizing the Therapeutic Potential of Adenosine as a Prophylactic and Acute Neuroprotectant

Stroke is a leading cause of morbidity and mortality in the United States. Despite intensive research into the development of treatments that lessen the severity of cerebrovascular injury, no major therapies exist. Though the potential use of adenosine as a neuroprotective agent in the context of stroke has long been realized, there are currently no adenosine-based therapies for the treatment of cerebral ischemia and reperfusion. One of the major obstacles to developing adenosine-based therapies for the treatment of stroke is the prevalence of functional adenosine receptors outside the central nervous system. The activities of peripheral immune and vascular endothelial cells are particularly vulnerable to modulation via adenosine receptors. Many of the pathophysiological processes in stroke are a direct result of peripheral immune infiltration into the brain. Ischemic preconditioning, which can be induced by a number of stimuli, has emerged as a promising area of focus in the development of stroke therapeutics. Reprogramming of the brain and immune responses to adenosine signaling may be an underlying principle of tolerance to cerebral ischemia. Insight into the role of adenosine in various preconditioning paradigms may lead to new uses for adenosine as both an acute and prophylactic neuroprotectant

Service Provider Views of Oxycontin Use on an Indian Reservation: Traumatic Effects on the Tribal Community

This is the publisher's version, also available electronically from http://alliance1.metapress.com/home/main.mpx.This qualitative research study on a Great Lakes Indian reservation used semistructured interviews of American Indian (n = 8) and non-American Indian (n = 2) providers of behavioral and physical health services to elicit views of Oxycontin use. We gathered data on existing substance abuse services including accessibility, cultural appropriateness, service strengths and weaknesses, barriers to treatment, and treatment needs. Results indicated a high prevalence of the use of Oxycontin, with traumatic effects on families and the tribal community such that the providers were overburdened with their dual role as service providers and caretakers in their own community. Implications for social work practice are discussed