New Evidence for Proton Cyclotron Resonance in a Magnetar Strength Field from SGR 1806-20

A great deal of evidence has recently been gathered in favor of the picture that Soft Gamma Repeaters and Anomalous X-Ray Pulsars are powered by ultra-strong magnetic fields (B > 10^{14} G; i.e. magnetars). Nevertheless, present determination of the magnetic field in such magnetar candidates has been indirect and model dependent. A key prediction concerning magnetars is the detection of ion cyclotron resonance features, which would offer a decisive diagnostic of the field strength. Here we present the detection of a 5 keV absorption feature in a variety of bursts from the Soft Gamma Repeater SGR 1806-20, confirming our initial discovery (Ibrahim et al. 2002) and establishing the presence of the feature in the source's burst spectra. The line feature is well explained as proton cyclotron resonance in an ultra-strong magnetic field, offering a direct measurement of SGR 1806-20's magnetic field (B ~ 10^{15} G) and a clear evidence of a magnetar. Together with the source's spin-down rate, the feature also provides the first measurement of the gravitational redshift, mass and radius of a magnetar.Comment: Accepted for Publication in ApJ

Discovery of a New Transient Magnetar Candidate: XTE J1810-197

We report the discovery of a new X-ray pulsar, XTE J1810-197. The source was serendipitously discovered on 2003 July 15 by the Rossi X-ray Timing Explorer (RXTE) while observing the soft gamma repeater SGR 1806-20. The pulsar has a 5.54 s spin-period and a soft spectrum (photon index ~ 4). We detect the source in earlier RXTE observations back to 2003 January. These show that a transient outburst began between 2002 November 17 and 2003 January 23 and that the pulsar has been spinning down since then, with a high rate Pdot ~ 10^-11 s/s showing significant timing noise, but no evidence for Doppler shifts due to a binary companion. The rapid spin-down rate and slow spin-period imply a super-critical magnetic field B=3x10^14 G and a young characteristic age < 7600 yr. These properties are strikingly similar to those of anomalous X-ray pulsars and soft gamma repeaters, making the source a likely new magnetar. A follow-up Chandra observation provided a 2".5 radius error circle within which the 1.5 m Russian-Turkish Optical Telescope RTT150 found a limiting magnitude of R_c=21.5, in accord with other recently reported limits. The source is present in archival ASCA and ROSAT data as well, at a level 100 times fainter than the \~ 3 mCrab seen in 2003. This suggests that other X-ray sources that are currently in a state similar to the inactive phase of XTE J1810-197 may also be unidentified magnetars awaiting detection via a similar activity.Comment: Submitted to ApJL; 4 pages; 4 figure

Alternatives for Scheduling Departures for Efficient Surface Metering in ATD-2: Exploration in a Human-in-the-Loop Simulation

Human-in-the-Loop (HITL) simulation was conducted to explore the impacts of various surface metering goals on operations and Ramp Controllers at Charlotte Douglas International Airport (CLT). Three conditions were compared: Baseline, with no surface metering, instructions to meet advisory times at the gate only, and instructions to meet advisory times at the gate as well as the times at the scheduled taxiway spot, where aircraft are delivered to Air Traffic Control (ATC). Results showed increased compliance for taxiway spot times when compliance was first met for gate advisories. Instructing Ramp Controllers to meet advisory times at the gate improves spot time compliance and therefore surface scheduling predictability at CLT. Results also demonstrated there was increased compliance overall with gate and spot times in the second condition. This was likely due to higher Ramp Controller workload in the third condition

How Hospitable Are Space Weather Affected Habitable Zones? The Role of Ion Escape

Atmospheres of exoplanets in the habitable zones around active young G-K-M stars are subject to extreme X-ray and EUV (XUV) fluxes from their host stars that can initiate atmospheric erosion. Atmospheric loss affects exoplanetary habitability in terms of surface water inventory, atmospheric pressure, the efficiency of greenhouse warming, and the dosage of the UV surface irradiation. Thermal escape models suggest that exoplanetary atmospheres around active K-M stars should undergo massive hydrogen escape, while heavier species including oxygen will accumulate forming an oxidizing atmosphere. Here, we show that non-thermal oxygen ion escape could be as important as thermal, hydrodynamic H escape in removing the constituents of water from exoplanetary atmospheres under supersolar XUV irradiation. Our models suggest that the atmospheres of a significant fraction of Earth-like exoplanets around M dwarfs and active K stars exposed to high XUV fluxes will incur a significant atmospheric loss rate of oxygen and nitrogen, which will make them uninhabitable within a few tens to hundreds of Myr, given a low replenishment rate from volcanism or cometary bombardment. Our non-thermal escape models have important implications for the habitability of the Proxima Centauri\u27s terrestrial planet

Additively manufactured artificial materials with metallic meta‐atoms

This is an Open Access Article. It is published by IET under the Creative Commons Attribution 3.0 Unported Licence (CC BY). Full details of this licence are available at: http://creativecommons.org/licenses/by/3.0/The paper presents the analysis and fabrication of artificial materials with metallic cuboid inclusions (termed here as meta-atoms) in a dielectric host material. These synthetic materials or metamaterials have been additively manufactured with a fused deposition modelling (FDM) 3D-printer. The effective permittivity and permeability have been numerically analyzed using the Maxwell-Garnett and Lewin’s approximation. Simulations and measurements have shown good agreement with analytical calculations. The anisotropy of the heterogeneous mixture due to the orientation of the meta-atoms has been demonstrated. The effective permittivity has been increased by the presence of the meta-atoms, which has the potential of producing 3D-printing metamaterials with tailored electromagnetic properties

Genes That Influence Swarming Motility and Biofilm Formation in Variovorax paradoxus EPS

Variovorax paradoxus is an aerobic soil bacterium associated with important biodegradative processes in nature. We use V. paradoxus EPS to study multicellular behaviors on surfaces.We recovered flanking sequence from 123 clones in a Tn5 mutant library, with insertions in 29 different genes, selected based on observed surface behavior phenotypes. We identified three genes, Varpa_4665, Varpa_4680, and Varpa_5900, for further examination. These genes were cloned into pBBR1MCS2 and used to complement the insertion mutants. We also analyzed expression of Varpa_4680 and Varpa_5900 under different growth conditions by qPCR.The 29 genes we identified had diverse predicted functions, many in exopolysaccharide synthesis. Varpa_4680, the most commonly recovered insertion site, encodes a putative N-acetyl-L-fucosamine transferase similar to WbuB. Expression of this gene in trans complemented the mutant fully. Several unique insertions were identified in Varpa_5900, which is one of three predicted pilY1 homologs in the EPS genome. No insertions in the two other putative pilY1 homologs present in the genome were identified. Expression of Varpa_5900 altered the structure of the wild type swarm, as did disruption of the chromosomal gene. The swarming phenotype was complemented by expression of Varpa_5900 from a plasmid, but biofilm formation was not restored. Both Varpa_4680 and Varpa_5900 transcripts were downregulated in biofilms and upregulated during swarming when compared to log phase culture. We identified a putative two component system (Varpa_4664-4665) encoding a response regulator (shkR) and a sensor histidine kinase (shkS), respectively. Biofilm formation increased and swarming was strongly delayed in the Varpa_4665 (shkS) mutant. Complementation of shkS restored the biofilm phenotype but swarming was still delayed. Expression of shkR in trans suppressed biofilm formation in either genetic background, and partially restored swarming in the mutant.The data presented here point to complex regulation of these surface behaviors

Effect of Hydrocortisone on Mortality and Organ Support in Patients With Severe COVID-19: The REMAP-CAP COVID-19 Corticosteroid Domain Randomized Clinical Trial.

Importance: Evidence regarding corticosteroid use for severe coronavirus disease 2019 (COVID-19) is limited. Objective: To determine whether hydrocortisone improves outcome for patients with severe COVID-19. Design, Setting, and Participants: An ongoing adaptive platform trial testing multiple interventions within multiple therapeutic domains, for example, antiviral agents, corticosteroids, or immunoglobulin. Between March 9 and June 17, 2020, 614 adult patients with suspected or confirmed COVID-19 were enrolled and randomized within at least 1 domain following admission to an intensive care unit (ICU) for respiratory or cardiovascular organ support at 121 sites in 8 countries. Of these, 403 were randomized to open-label interventions within the corticosteroid domain. The domain was halted after results from another trial were released. Follow-up ended August 12, 2020. Interventions: The corticosteroid domain randomized participants to a fixed 7-day course of intravenous hydrocortisone (50 mg or 100 mg every 6 hours) (n = 143), a shock-dependent course (50 mg every 6 hours when shock was clinically evident) (n = 152), or no hydrocortisone (n = 108). Main Outcomes and Measures: The primary end point was organ support-free days (days alive and free of ICU-based respiratory or cardiovascular support) within 21 days, where patients who died were assigned -1 day. The primary analysis was a bayesian cumulative logistic model that included all patients enrolled with severe COVID-19, adjusting for age, sex, site, region, time, assignment to interventions within other domains, and domain and intervention eligibility. Superiority was defined as the posterior probability of an odds ratio greater than 1 (threshold for trial conclusion of superiority >99%). Results: After excluding 19 participants who withdrew consent, there were 384 patients (mean age, 60 years; 29% female) randomized to the fixed-dose (n = 137), shock-dependent (n = 146), and no (n = 101) hydrocortisone groups; 379 (99%) completed the study and were included in the analysis. The mean age for the 3 groups ranged between 59.5 and 60.4 years; most patients were male (range, 70.6%-71.5%); mean body mass index ranged between 29.7 and 30.9; and patients receiving mechanical ventilation ranged between 50.0% and 63.5%. For the fixed-dose, shock-dependent, and no hydrocortisone groups, respectively, the median organ support-free days were 0 (IQR, -1 to 15), 0 (IQR, -1 to 13), and 0 (-1 to 11) days (composed of 30%, 26%, and 33% mortality rates and 11.5, 9.5, and 6 median organ support-free days among survivors). The median adjusted odds ratio and bayesian probability of superiority were 1.43 (95% credible interval, 0.91-2.27) and 93% for fixed-dose hydrocortisone, respectively, and were 1.22 (95% credible interval, 0.76-1.94) and 80% for shock-dependent hydrocortisone compared with no hydrocortisone. Serious adverse events were reported in 4 (3%), 5 (3%), and 1 (1%) patients in the fixed-dose, shock-dependent, and no hydrocortisone groups, respectively. Conclusions and Relevance: Among patients with severe COVID-19, treatment with a 7-day fixed-dose course of hydrocortisone or shock-dependent dosing of hydrocortisone, compared with no hydrocortisone, resulted in 93% and 80% probabilities of superiority with regard to the odds of improvement in organ support-free days within 21 days. However, the trial was stopped early and no treatment strategy met prespecified criteria for statistical superiority, precluding definitive conclusions. Trial Registration: ClinicalTrials.gov Identifier: NCT02735707