Elemental surface analysis at ambient pressure by electron-induced x-ray fluorescence

The development of a portable surface elemental analysis tool, based on the excitation of characteristic x rays from samples at ambient pressure with a focused electron beam is described. This instrument relies on the use of a thin electron transmissive membrane to isolate the vacuum of the electron source from the ambient atmosphere. The major attributes of this instrument include rapid (several minutes) spectrum acquisition, nondestructive evaluation of elemental composition, no sample preparation, and high-to-medium (several hundreds µm) spatial resolution. The instrument proof-of-principle has been demonstrated in a laboratory setup by obtaining energy dispersive x-ray spectra from metal and mineral samples

Atmospheric electron x-ray spectrometer

The present invention comprises an apparatus for performing in-situ elemental analyses of surfaces. The invention comprises an atmospheric electron x-ray spectrometer with an electron column which generates, accelerates, and focuses electrons in a column which is isolated from ambient pressure by a:thin, electron transparent membrane. After passing through the membrane, the electrons impinge on the sample in atmosphere to generate characteristic x-rays. An x-ray detector, shaping amplifier, and multi-channel analyzer are used for x-ray detection and signal analysis. By comparing the resultant data to known x-ray spectral signatures, the elemental composition of the surface can be determined

Antinociception Following Implantation of AtT-20 and Genetically Modified AtT-20/hENK Cells in Rat Spinal Cord

AtT-20 cells, which produce β-endorphin, and AtT-20/hENK cells, which are AtT-20 cells transfected with a proenkephalin gene, were implanted in the rat spinal subarachnoid space in an effort to produce an antinociceptive effect. Host rats were tested for antinociceptive activity by standard nociceptive tests, tail flick and hot plate. Although cell implants had minimal effect on the basal response to thermal nociceptive stimuli, administration of the β2-adrenergic agonist isoproterenol produced antinociception in the cell-implanted group but not in the control group. The antinociceptive effect of isoproterenol was dose-related and could be blocked by the opioid antagonist naloxone. Immunohistochemical analysis of spinal cords revealed the presence of enkephalin-negative cells surrounding the spinal cord of rats receiving AtT-20 cell implants, and enkephalinpositive cells surrounding the spinal cord of rats. receiving AtT-20/hENK cell implants. These results suggest that opioid-releasing cells implanted around rat spinal cord can produce antinociception and may provide an alternative therapy for chronic pain

1865-11-02 George Wilcox of the Assessor\u27s Office inquires about Benjamin C. Fogg of Company G, who was detached to the U.S. Sanitary Commission

https://digitalmaine.com/cw_me_1st_heavy_corr/1444/thumbnail.jp

A handbook of Nebraska grasses : with illustrated keys for their identification, together with a general account of their structure and economic importance

The true grasses belong to the one family Poaceae, often called Gramineae, and constitute a very well defined natural group of plants. This family comprises upward of 3,000 species distributed among almost 300 genera. From the economic point of view the family is of supreme importance thru the fact that here belong the cereals, which supply a large part of the food of man, and the forage grasses which are so important as feed for our domesticated animals. The genera and species are for the most part separated by artificial characters—a fact which renders their study and identification extremely difficult even for the expert. The experience of the authors has convinced them that much of this difficulty is to be credited to the keys found in our common manuals. Theoretically a key is intended to assist one in properly identifying a plant, but actually many of the keys, upon close inspection. are found to contain so many vague and contradictory statements that they can be depended upon only by the expert who, on account of his working knowledge, makes slight use of the keys. It occurred to the senior author some years ago that an illustrated key might solve many of these difficulties. An accurate illustration conveys a more definite idea of any particular structure and leaves less room for doubt than any number of words. In fact, the serious and annoying inaccuracies of most keys to the grasses became more and more apparent as the work of preparing the illustrations progressed. The authors are fully convinced that illustrated keys of the type here employed will prove useful in many other groups of plants. The nomenclature here employed is largely that of the seventh edition of Gray\u27s Manual—tho our purpose has not been to insist upon any particular name but to provide means whereby the student can with some certainty attach to any given plant some one name which has been properly authorized. The present key includes most of the species known to occur in Nebraska, tho a few of minor importance and very restricted distribution have been omitted. There are provided also some data on the economic value of certain of the most important species. The illustrations for the grass keys have been drawn expressly for this publication. They are derived in part from actual authentic specimens and in part redrawn in modified form from various manuals and monographs. T he authors have made free use of the manuals, monographs. etc., included in the Bibliography and take this opportunity to commend these publications to the attention of all who wish to learn more of our common grasses. It is hoped that the keys here presented will facilitate the study of the grass flora of Nebraska by farmers and students

Bias Associated with Mining Electronic Health Records

Large-scale electronic health record research introduces biases compared to traditional manually curated retrospective research. We used data from a community-acquired pneumonia study for which we had a gold standard to illustrate such biases. The challenges include data inaccuracy, incompleteness, and complexity, and they can produce in distorted results. We found that a naïve approach approximated the gold standard, but errors on a minority of cases shifted mortality substantially. Manual review revealed errors in both selecting and characterizing the cohort, and narrowing the cohort improved the result. Nevertheless, a significantly narrowed cohort might contain its own biases that would be difficult to estimate

Fitness, Friendship, and Fun: University Sponsored Community PE Program

This paper describes a University-sponsored community physical education program and the feedback received about it from teachers, children, and the college students who oversaw it. The program, called Fitness, Friendship, and Fun, was staffed by 65 first-year student interns from the University of Dayton; four graduate assistants; and two university professors. It began with 65 male and female elementary students, primarily from the fifth and sixth grades at a nearby elementary school

Atmospheric electron X-ray spectrometer development

The development of a portable surface elemental analysis tool based on the excitation of characteristic X-rays at ambient pressure with an electron beam is described. This instrument relies on the use of a thin electron transmissive membrane to isolate the vacuum of the electron source from the ambient atmosphere. The major advantages offered by this instrument include rapid spectrum acquisition, nondestructive evaluation of elemental composition, and high spatial resolution in comparison to similar portable instruments. The instrument proof-of-principle has been demonstrated by obtaining energy dispersive X-ray spectra from metal and mineral samples. SEM experiments have been carried out to determine beam spot size and quantitative analysis limits. Modeling has been performed to study performance limits and to understand the influence of membrane and atmosphere interactions on the focused electron beam

Dune Evolution Accomack County, Virginia Chesapeake Bay Shorelines

Shoreline evolution is the change in shore position through time. In fact, it is the material resistance of the coastal geologic underpinnings against the impinging hydrodynamic (and aerodynamic) forces. Along the shores of Chesapeake Bay, it is a process-response system. The processes at work include winds, waves, tides and currents, which shape and modify coastlines by eroding, transporting and depositing sediments. The shore line is commonly plotted and measured to provide a rate of change but it is as important to understand the geomorphic patterns of change. Shore analysis provides the basis to know how a particular coast has changed through time and how it might proceed in the future. The purpose of this report is to document how the dunes on Chesapeake Bay shores of Accomack (Figure 1) have evolved since 1938. Aerial imagery was taken for most of the Bay region beginning that year, and it is this imagery that allows one to assess the geomorphic nature of shore change. Aerial imagery shows how the coast has changed, how beaches, dunes, bars, and spits have grown or decayed, how barriers have breached, how inlets have changed course, and how one shore type has displaced another or has not changed at all. Shore change is a natural process but, quite often, the impacts of man through shore hardening or inlet stabilization come to dominate a given shore reach. Most of the change in shore positions where dunes occur will be quantified in this report. Others, particularly very irregular coasts, around inlets, and other complicated areas will be subject to interpretation