25 research outputs found
Down Conversion Scheme for PDV
Author Institution: Lawrence Livermore National LaboratorySlides presented at the 2nd Annual Photonic Doppler Velocimetry (PDV) Workshop held at Lawrence Livermore National Laboratory, Livermore, California, August 16-17, 2007
Factors to Consider when Choosing a Probe
Author Institution: Lawrence Livermore National LaboratorySlides presented at the 3nd Annual Photonic Doppler Velocimetry (PDV) Conference and Workshop held at Sandia National Laboratories, Albuquerque, New Mexico, September 3-4, 2008
Processing Oscillatory Data with PDV
Author Institution: Lawrence Livermore National LaboratorySlides presented at the 2nd Annual Photonic Doppler Velocimetry (PDV) Workshop held at Lawrence Livermore National Laboratory, Livermore, California, August 16-17, 2007
Embedded Fiber Optic Probes to Measure Detonation Velocities Using the PDV
Author Institution: Lawrence Livermore National LaboratoryAuthor Institution: Los Alamos National LaboratorySlides presented at the 5th Annual Photonic Doppler Velocimetry (PDV) Users Conference held at The Ohio State University, Columbus, Ohio, September 8-9, 2010
What are the Limits of PDV?
Author Institution: Lawrence Livermore National LaboratorySlides presented at the Heterodyne Velocimeter Workshop held at Lawrence Livermore National Laboratory, Livermore, California, July 20-21, 2006
GWAS meta-analysis of intrahepatic cholestasis of pregnancy implicates multiple hepatic genes and regulatory elements
Intrahepatic cholestasis of pregnancy (ICP) is a pregnancy-specific liver disorder affecting 0.5–2% of pregnancies. The majority of cases present in the third trimester with pruritus, elevated serum bile acids and abnormal serum liver tests. ICP is associated with an increased risk of adverse outcomes, including spontaneous preterm birth and stillbirth. Whilst rare mutations affecting hepatobiliary transporters contribute to the aetiology of ICP, the role of common genetic variation in ICP has not been systematically characterised to date. Here, we perform genome-wide association studies (GWAS) and meta-analyses for ICP across three studies including 1138 cases and 153,642 controls. Eleven loci achieve genome-wide significance and have been further investigated and fine-mapped using functional genomics approaches. Our results pinpoint common sequence variation in liver-enriched genes and liver-specific cis-regulatory elements as contributing mechanisms to ICP susceptibility
All-in-one PDV (APDV) Control, Analysis, and Reporting Software
Author Insitution: Lawrence Livermore National LaboratorySlides presented at the 2014 Photonic Doppler Velocimetry (PDV) Workshop Hosted by National Security Technologies, LLC, and the University of Nevada Las Vegas, June 24-26, 2014, Las Vegas, Nevada
Duplexing Data
Author Institution: Lawrence Livermore National LaboratorySlides presented at the 6th Annual Photonic Doppler Velocimetry (PDV) Workshop held at Lawrence Livermore National Laboratory, Livermore, California, November 3-4, 2011
Embedded Fiber Optical Probes
Author Institution: Lawrence Livermore National LaboratoryAuthor Institution: Los Alamos National LaboratorySlides presented at the 2nd Annual Photonic Doppler Velocimetry (PDV) Workshop held at Lawrence Livermore National Laboratory, Livermore, California, August 16-17, 2007