753 research outputs found
Hunter Activities, Conflicts, and Opinions Following Implementation of a Controlled Waterfowl Hunting Program on the Rend Lake Public Hunting Area in 1995-96
Waterfowl Program Periodic Report no. 90Report issued on: 2 December 199
Non-additivity of van der Waals forces on liquid surfaces
We present an approach for modeling nanoscale wetting and dewetting of liquid
surfaces that exploits recently developed, sophisticated techniques for
computing van der Waals (vdW) or (more generally) Casimir forces in arbitrary
geometries. We solve the variational formulation of the Young--Laplace equation
to predict the equilibrium shapes of fluid--vacuum interfaces near solid
gratings and show that the non-additivity of vdW interactions can have a
significant impact on the shape and wetting properties of the liquid surface,
leading to very different surface profiles and wetting transitions compared to
predictions based on commonly employed additive approximations, such as Hamaker
or Derjaguin approximations.Comment: 5 pages (including abstract, acknowledgments, and references), 3
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Expressed sequence tag survey of gene expression in the scab mite Psoroptes ovis--allergens, proteases and free-radical scavengers
Recurrent depression and relational trauma: a single case of memory processing
\ua9 2024 The Author(s). Published by Cambridge University Press on behalf of British Association for Behavioural and Cognitive Psychotherapies. Cognitive behavioural therapy (CBT) is an effective treatment for depression, but a significant minority of clients are difficult to treat, including those with histories of relational trauma. The model of Beck et al. (1979) proposes that adverse childhood experiences lead to negative core beliefs, and these create a susceptibility to depression. However, Beck\u27s model does not identify trauma as a subset of adverse experiences. An alternative view is that traumatised clients internalise conflicting representations of self and it is conflict, interacting with trauma memories, that creates a vulnerability for depression. In this formulation, methods from the treatment of post-traumatic stress disorder (PTSD) could be incorporated into the treatment of depression, to emotionally process trauma memories and resolve self-identity conflicts. The aims of this study were to: (1) report the treatment of a 67-year-old man with recurrent depression and a history of prolonged relational trauma, and (2) to explore how memory processing from the treatment of PTSD can be incorporated into the treatment of recurrent depression. A single case observational design was used in the long-term treatment of a depressed traumatised client. The client received 47 individual sessions over 19 months in routine clinical practice in a tertiary CBT service. He completed repeated measures of mood, memory intrusions and sleep disruption. The client responded well to treatment with clinically significant improvements across measures of mood, memory and sleep. The effects were sustained over an 18-month follow-up. Memory processing was successfully integrated into a high-intensity treatment for recurrent depression. This is a promising approach for depressed clients with histories of relational trauma. Key learning aims (1) To consider how imaginal reliving can be incorporated into CBT for recurrent depression, when relational trauma is present. (2) To consider the cognitive processing mode of depressed traumatised clients when appraising beliefs about self and others. (3) To consider vulnerability to depression based on intrusive memories and conflicting self-representations, not only core beliefs
High dose BCNU chemotherapy with autologous bone marrow transplantation and full dose radiotherapy for grade IV astrocytoma.
In a series of 22 patients, high dose BCNU (800-1,000mg m-2) with autologous bone marrow transplantation was given as the first post-surgical treatment for grade IV astrocytoma and followed by full dose radiotherapy. When compared to historical experience and matched to control patients in national studies, there appeared to be a small prolongation of survival but no increase in the proportion of long survivors. Acute myelosuppression was mild but toxicity to lung and liver was substantial and limited further dose escalation. Late bone marrow failure was seen in 4 patients. Pharmacokinetic studies were performed and suggested that the late marrow failure was due to persistence of BCNU at the time of marrow return. Despite the suggestion of a prolongation of survival this approach is not routinely recommended and a randomised trial is probably not justified
Serverāside workflow execution using data grid technology for reproducible analyses of dataāintensive hydrologic systems
Many geoscience disciplines utilize complex computational models for advancing understanding and sustainable management of Earth systems. Executing such models and their associated data preprocessing and postprocessing routines can be challenging for a number of reasons including (1) accessing and preprocessing the large volume and variety of data required by the model, (2) postprocessing large data collections generated by the model, and (3) orchestrating data processing tools, each with unique software dependencies, into workflows that can be easily reproduced and reused. To address these challenges, the work reported in this paper leverages the Workflow Structured Object functionality of the Integrated RuleāOriented Data System and demonstrates how it can be used to access distributed data, encapsulate hydrologic data processing as workflows, and federate with other communityādriven cyberinfrastructure systems. The approach is demonstrated for a study investigating the impact of drought on populations in the Carolinas region of the United States. The analysis leverages computational modeling along with data from the Terra Populus project and data management and publication services provided by the Sustainable EnvironmentāActionable Data project. The work is part of a larger effort under the DataNet Federation Consortium project that aims to demonstrate data and computational interoperability across cyberinfrastructure developed independently by scientific communities.Plain Language SummaryExecuting computational workflows in the geosciences can be challenging, especially when dealing with large, distributed, and heterogeneous data sets and computational tools. We present a methodology for addressing this challenge using the Integrated RuleāOriented Data System (iRODS) Workflow Structured Object (WSO). We demonstrate the approach through an endātoāend application of data access, processing, and publication of digital assets for a scientific study analyzing drought in the Carolinas region of the United States.Key PointsReproducibility of dataāintensive analyses remains a significant challengeData grids are useful for reproducibility of workflows requiring large, distributed data setsData and computations should be coālocated on servers to create executable WebāresourcesPeer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/137520/1/ess271_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/137520/2/ess271.pd
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