505 research outputs found

    A Meditative Art

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    My artwork symbolizes the idea of meditation through the true and organic forms. I paint a space where my mind is at ease. A place where all the chaos of the world around me stops and become beauty. In my artwork, the organic forms that I produce reflect the meditative power of natural forms. My mind sees the environment in a simple abstract appearance that mirrors a sense of peace and harmony. By painting with smooth, organic, and soft lines my artwork helps me get to a point of relaxation. Through the process of letting go of the world that surrounds me, I am at ease as I create. My hope is that each painting inspires a person to visually ponder and become lost within his or her thoughts

    Reflections on Math Students’ Circles: Two Personal Stories from Colorado

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    Math Students’ Circles provide an opportunity for mathematicians to work in their communities to engage young students in mathematics as a human, aesthetic, and social endeavor. Sometimes referred to simply as Math Circles, these venues give mathematicians experience in introducing children to topics not typically seen in school curricula in an exciting, hands-on format. This article explores two Math Students’ Circles (MSCs) in the state of Colorado from the point of view of two pre-tenure faculty members. One participated in MSCs for four years while working on her Ph.D. in mathematics, the other started an MSC as an offshoot of a successful professional development program for middle school mathematics teachers. We discuss how and why MSCs have influenced our professional lives

    Identification of known and novel pancreas genes expressed downstream of Nkx2.2 during development

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    <p>Abstract</p> <p>Background</p> <p>The homeodomain containing transcription factor Nkx2.2 is essential for the differentiation of pancreatic endocrine cells. Deletion of Nkx2.2 in mice leads to misspecification of islet cell types; insulin-expressing β cells and glucagon-expressing α cells are replaced by ghrelin-expressing cells. Additional studies have suggested that Nkx2.2 functions both as a transcriptional repressor and activator to regulate islet cell formation and function. To identify genes that are potentially regulated by Nkx2.2 during the major wave of endocrine and exocrine cell differentiation, we assessed gene expression changes that occur in the absence of Nkx2.2 at the onset of the secondary transition in the developing pancreas.</p> <p>Results</p> <p>Microarray analysis identified 80 genes that were differentially expressed in e12.5 and/or e13.5 Nkx2.2<sup>-/- </sup>embryos. Some of these genes encode transcription factors that have been previously identified in the pancreas, clarifying the position of Nkx2.2 within the islet transcriptional regulatory pathway. We also identified signaling factors and transmembrane proteins that function downstream of Nkx2.2, including several that have not previously been described in the pancreas. Interestingly, a number of known exocrine genes are also misexpressed in the Nkx2.2<sup>-/- </sup>pancreas.</p> <p>Conclusions</p> <p>Expression profiling of Nkx2.2<sup>-/- </sup>mice during embryogenesis has allowed us to identify known and novel pancreatic genes that function downstream of Nkx2.2 to regulate pancreas development. Several of the newly identified signaling factors and transmembrane proteins may function to influence islet cell fate decisions. These studies have also revealed a novel function for Nkx2.2 in maintaining appropriate exocrine gene expression. Most importantly, Nkx2.2 appears to function within a complex regulatory loop with Ngn3 at a key endocrine differentiation step.</p

    Mind the Gap: Student Researchers Use Secondary Data to Explore Disparities in STEM Education

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    Large data sets offer opportunities for graduate students to become involved in meaningful research, but also comes with a unique set of challenges. This paper seeks to examine that relationship through utilizing the High School Longitudinal Study 2009 – representative of US ninth graders in 2009 (n = 21,444) – to examine a set of research questions about STEM interest and preparation amongst secondary students. Student researchers identified gaps in plans and outcomes with regards to race, gender, exceptionalities, and socioeconomic status. Findings indicated inequities that affect STEM outcomes. A significant interaction was found between students education expectations by gender on science self-efficacy [F(4,1264) = 2.797, p =.025]. This interaction was not observed for math self-efficacy. Females and underrepresented minorities were less likely to pursue computer science courses and computer science careers [Females: Χ2 (2, N = 20,594) = 111.500, p \u3c .0001; Minorities: Χ2 (2, N = 13,069) = 6.455, p = .040]. Students’ expectations for post-secondary education differed by IEP status and socioeconomic status [Χ2 (3, n =165,684) = 26.886, p = 0.001]. Finally, time spent in extracurricular activities impacted academic achievement and students in lower socioeconomic groups were less involved in extracurricular activities [Χ2 (4, n = 20,598) = 132.298, p \u3c .0001]

    Mitigating intensive care unit noise: Design-led modeling solutions, calculated acoustic outcomes, and cost implications

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    Objectives, Purpose, or Aim: The study aimed to decrease noise levels in the ICU, anticipated to have adverse effects on both patients and staff, by implementing enhancements in acoustic design. Background: Recognizing ICU noise as a significant disruptor of sleep and a potential hindrance to patient recovery, this study was conducted at a 40-bed ICU in Fiona Stanley Hospital in Perth, Australia. Methods: A comprehensive mixed-methods approach was employed, encompassing surveys, site analysis, and acoustic measurements. Survey data highlighted the importance of patient sleep quality, emphasizing the negative impact of noise on work performance, patient connection, and job satisfaction. Room acoustics analysis revealed noise levels ranging from 60 to 90 dB(A) in the presence of patients, surpassing sleep disruption criteria. Results: Utilizing an iterative 3D design modeling process, the study simulated significant acoustic treatment upgrades. The design integrated effective acoustic treatments within patient rooms, aiming to reduce noise levels and minimize transmission to adjacent areas. Rigorous evaluation using industry-standard acoustic software highlights the design’s efficacy in reducing noise transmission in particular. Additionally, cost implications were examined, comparing standard ICU construction with acoustically treated options for new construction and refurbishment projects. Conclusions: This study provides valuable insights into design-based solutions for addressing noise-related challenges in the ICU. While the focus is on improving the acoustic environment by reducing noise levels and minimizing transmission to adjacent areas. It is important to clarify that direct measurements of patient outcomes were not conducted. The potential impact of these solutions on health outcomes, particularly sleep quality, remains a crucial aspect for consideration

    Semi-automated surface water detection with synthetic aperture radar data: A wetland case study

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    In this study, a new method is proposed for semi-automated surface water detection using synthetic aperture radar data via a combination of radiometric thresholding and image segmentation based on the simple linear iterative clustering superpixel algorithm. Consistent intensity thresholds are selected by assessing the statistical distribution of backscatter values applied to the mean of each superpixel. Higher-order texture measures, such as variance, are used to improve accuracy by removing false positives via an additional thresholding process used to identify the boundaries of water bodies. Results applied to quad-polarized RADARSAT-2 data show that the threshold value for the variance texture measure can be approximated using a constant value for different scenes, and thus it can be used in a fully automated cleanup procedure. Compared to similar approaches, errors of omission and commission are improved with the proposed method. For example, we observed that a threshold-only approach consistently tends to underestimate the extent of water bodies compared to combined thresholding and segmentation, mainly due to the poor performance of the former at the edges of water bodies. The proposed method can be used for monitoring changes in surface water extent within wetlands or other areas, and while presented for use with radar data, it can also be used to detect surface water in optical images

    Moving to the RADARSAT Constellation Mission: Comparing Synthesized Compact Polarimetry and Dual Polarimetry Data with Fully Polarimetric RADARSAT-2 Data for Image Classification of Peatlands

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    For this research, the Random Forest (RF) classifier was used to evaluate the potential of simulated RADARSAT Constellation Mission (RCM) data for mapping landcover within peatlands. Alfred Bog, a large peatland complex in Southern Ontario, was used as a test case. The goal of this research was to prepare for the launch of the upcoming RCM by evaluating three simulated RCM polarizations for mapping landcover within peatlands. We examined (1) if a lower RCM noise equivalent sigma zero (NESZ) affects classification accuracy, (2) which variables are most important for classification, and (3) whether classification accuracy is affected by the use of simulated RCM data in place of the fully polarimetric RADARSAT-2. Results showed that the two RCM NESZs (−25 dB and −19 dB) and three polarizations (compact polarimetry, HH+HV, and VV+VH) that were evaluated were all able to achieve acceptable classification accuracies when combined with optical data and a digital elevation model (DEM). Optical variables were consistently ranked to be the most important for mapping landcover within peatlands, bu

    X-ray Properties of Intermediate-Redshift Groups of Galaxies

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    We have undertaken a multiwavelength project to study the relatively unknown properties of groups and poor clusters of galaxies at intermediate redshifts. In this paper, we describe the XMM-Newton observations of six X-ray selected groups with 0.2<z<0.6. The X-ray properties of these systems are generally in good agreement with the properties of low-redshift groups. They appear to follow the scaling relations between luminosity, temperature, and velocity dispersion defined by low-redshift groups and clusters. The X-ray emission in four of the six groups is also centered on a dominant early-type galaxy. The lack of a bright elliptical galaxy at the peak of the group X-ray emission is rare at low-redshifts, and the other two groups may be less dynamically evolved. We find indications of excess entropy in these systems over self-similar predictions out to large radii. We also confirm the presence of at least one X-ray luminous AGN associated with a group member galaxy and find several other potential group AGN.Comment: 31 pages, 13 figures, accepted to ApJ for version with full resolution figures see http://www.ociw.edu/~tesla/midzgroups.ps.g

    Upward revision of global fossil fuel methane emissions based on isotope database

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    Methane has the second-largest global radiative forcing impact of anthropogenic greenhouse gases after carbon dioxide, but our understanding of the global atmospheric methane budget is incomplete. The global fossil fuel industry (production and usage of natural gas, oil and coal) is thought to contribute 15 to 22 per cent of methane emissions to the total atmospheric methane budget. However, questions remain regarding methane emission trends as a result of fossil fuel industrial activity and the contribution to total methane emissions of sources from the fossil fuel industry and from natural geological seepage, which are often co-located. Here we re-evaluate the global methane budget and the contribution of the fossil fuel industry to methane emissions based on long-term global methane and methane carbon isotope records. We compile the largest isotopic methane source signature database so far, including fossil fuel, microbial and biomass-burning methane emission sources. We find that total fossil fuel methane emissions (fossil fuel industry plus natural geological seepage) are not increasing over time, but are 60 to 110 per cent greater than current estimates owing to large revisions in isotope source signatures. We show that this is consistent with the observed global latitudinal methane gradient. After accounting for natural geological methane seepage, we find that methane emissions from natural gas, oil and coal production and their usage are 20 to 60 per cent greater than inventories. Our findings imply a greater potential for the fossil fuel industry to mitigate anthropogenic climate forcing, but we also find that methane emissions from natural gas as a fraction of production have declined from approximately 8 per cent to approximately 2 per cent over the past three decades.Published88-916A. Geochimica per l'ambienteJCR Journa

    The Grizzly, February 24, 1997

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    Dr. Gaede Receives $28,500 Grant • Organist and Dancer to Perform at Ursinus • Dr. Goetz to Lecture • Greek Life Discussion at Common Hour • Opinion: Things That Make Me Go Hmmm; Letters from Great Britain; A Non-Greek Speaks Back; Go Out and Do Something; Student Ponders Greek Life; Politicians\u27 Greed Outweighs Desires of Constituents • Daniel Pipes to Lecture on the Middle East • Torsone Wins 118-Pound Regional Title • Women\u27s Basketball Drops Two in a Row • Larkin Honored Twice • Gymnastics Place Third at Ithaca Invitational • Buyse Scores 1,000th Pointhttps://digitalcommons.ursinus.edu/grizzlynews/1398/thumbnail.jp
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