54,890 research outputs found
The impact of charge symmetry and charge independence breaking on the properties of neutrons and protons in isospin-asymmetric nuclear matter
We investigate the effects of charge independence and charge symmetry
breaking in neutron-rich matter. We consider neutron and proton properties in
isospin-asymmetric matter at normal densities as well as the high-density
neutron matter equation of state and the bulk properties of neutron stars. We
find charge symmetry and charge independence breaking effects to be very small.Comment: 6 pages, 8 figure
Application of redundancy in the Saturn 5 guidance and control system
The Saturn launch vehicle's guidance and control system is so complex that the reliability of a simplex system is not adequate to fulfill mission requirements. Thus, to achieve the desired reliability, redundancy encompassing a wide range of types and levels was employed. At one extreme, the lowest level, basic components (resistors, capacitors, relays, etc.) are employed in series, parallel, or quadruplex arrangements to insure continued system operation in the presence of possible failure conditions. At the other extreme, the highest level, complete subsystem duplication is provided so that a backup subsystem can be employed in case the primary system malfunctions. In between these two extremes, many other redundancy schemes and techniques are employed at various levels. Basic redundancy concepts are covered to gain insight into the advantages obtained with various techniques. Points and methods of application of these techniques are included. The theoretical gain in reliability resulting from redundancy is assessed and compared to a simplex system. Problems and limitations encountered in the practical application of redundancy are discussed as well as techniques verifying proper operation of the redundant channels. As background for the redundancy application discussion, a basic description of the guidance and control system is included
The formation of ion acoustic shocks
Recent experiments performed in the double plasma (DP) device have verified the existence of electrostatic ion acoustic laminar shocks. The influence of the piston on the shock structure is investigated by modeling the DP device and by numerically solving the temporal and spatial evolution of the shock. In order to isolate piston effects, as opposed to kinetic theory effects such as reflected ions and trapped electrons, the DP plasma is modeled as a cold ion fluid with isothermal Boltzmann electrons. It is shown that laminar shock transitions with structure agreeing with DP shock experiments can be excited
The impact of prior information on estimates of disease transmissibility using Bayesian tools
The basic reproductive number (R₀) and the distribution of the serial interval (SI) are often used to quantify transmission during an infectious disease outbreak. In this paper, we present estimates of R₀ and SI from the 2003 SARS outbreak in Hong Kong and Singapore, and the 2009 pandemic influenza A(H1N1) outbreak in South Africa using methods that expand upon an existing Bayesian framework. This expanded framework allows for the incorporation of additional information, such as contact tracing or household data, through prior distributions. The results for the R₀ and the SI from the influenza outbreak in South Africa were similar regardless of the prior information (R0 = 1.36-1.46, μ = 2.0-2.7, μ = mean of the SI). The estimates of R₀ and μ for the SARS outbreak ranged from 2.0-4.4 and 7.4-11.3, respectively, and were shown to vary depending on the use of contact tracing data. The impact of the contact tracing data was likely due to the small number of SARS cases relative to the size of the contact tracing sample
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Beyond Critical Period Learning: Striatal FoxP2 Affects the Active Maintenance of Learned Vocalizations in Adulthood.
In humans, mutations in the transcription factor forkhead box P2 (FOXP2) result in language disorders associated with altered striatal structure. Like speech, birdsong is learned through social interactions during maturational critical periods, and it relies on auditory feedback during initial learning and on-going maintenance. Hearing loss causes learned vocalizations to deteriorate in adult humans and songbirds. In the adult songbird brain, most FoxP2-enriched regions (e.g., cortex, thalamus) show a static expression level, but in the striatal song control nucleus, area X, FoxP2 is regulated by singing and social context: when juveniles and adults sing alone, its levels drop, and songs are more variable. When males sing to females, FoxP2 levels remain high, and songs are relatively stable: this "on-line" regulation implicates FoxP2 in ongoing vocal processes, but its role in the auditory-based maintenance of learned vocalization has not been examined. To test this, we overexpressed FoxP2 in both hearing and deafened adult zebra finches and assessed effects on song sung alone versus songs directed to females. In intact birds singing alone, no changes were detected between songs of males expressing FoxP2 or a GFP construct in area X, consistent with the marked stability of mature song in this species. In contrast, songs of males overexpressing FoxP2 became more variable and were less preferable to females, unlike responses to songs of GFP-expressing control males. In deafened birds, song deteriorated more rapidly following FoxP2 overexpression relative to GFP controls. Together, these experiments suggest that behavior-driven FoxP2 expression and auditory feedback interact to precisely maintain learned vocalizations
Microplankton species assemblages at the Scripps Pier from March to November 1983 during the 1982-1984 El Nino event
A semiweekly sampling program at the Scripps Institution of Oceanography pier was begun in 1983 during an El Nino event. Microplankton data for March to November 1983 show a temporal sequence of species assemblages of the 24 important taxa, with a residence time of 1 to 4 weeks. From March to early September, the assemblages consisted of typical neritic taxa. From mid-September to mid-November, the presence of oceanic warm-wave species was associated with positive temperature anomalies characteristic of the El Nino condition. During the period studied numerical abundances were low
Is Cosmology Solved?
We have fossil evidence from the thermal background radiation that our
universe expanded from a considerably hotter denser state. We have a well
defined and testable description of the expansion, the relativistic
Friedmann-Lemaitre model. Its observational successes are impressive but I
think hardly enough for a convincing scientific case. The lists of
observational constraints and free hypotheses within the model have similar
lengths. The scorecard on the search for concordant measures of the mass
density parameter and the cosmological constant shows that the high density
Einstein-de Sitter model is challenged, but that we cannot choose between low
density models with and without a cosmological constant. That is, the
relativistic model is not strongly overconstrained, the usual test of a mature
theory. Work in progress will greatly improve the situation and may at last
yield a compelling test. If so, and the relativistic model survives, it will
close one line of research in cosmology: we will know the outlines of what
happened as our universe expanded and cooled from high density. It will not end
research: some of us will occupy ourselves with the details of how galaxies and
other large-scale structures came to be the way they are, others with the issue
of what our universe was doing before it was expanding. The former is being
driven by rapid observational advances. The latter is being driven mainly by
theory, but there are hints of observational guidance.Comment: 13 pages, 3 figures. To be published in PASP as part of the
proceedings of the Smithsonian debate, Is Cosmology Solved
To what extent does severity of loneliness vary among different mental health diagnostic groups: A cross-sectional study.
Loneliness is a common and debilitating problem in individuals with mental health disorders. However, our knowledge on severity of loneliness in different mental health diagnostic groups and factors associated with loneliness is poor, thus limiting the ability to target and improve loneliness interventions. The current study investigated the association between diagnoses and loneliness and explored whether psychological and social factors were related to loneliness. This study employed a cross-sectional design using data from a completed study which developed a measure of social inclusion. It included 192 participants from secondary, specialist mental health services with a primary diagnosis of psychotic disorders (n = 106), common mental disorders (n = 49), or personality disorders (n = 37). The study explored differences in loneliness between these broad diagnostic groups, and the relationship to loneliness of: affective symptoms, social isolation, perceived discrimination, and internalized stigma. The study adhered to the STROBE checklist for observational research. People with common mental disorders (MD = 3.94, CI = 2.15 to 5.72, P < 0.001) and people with personality disorders (MD = 4.96, CI = 2.88 to 7.05, P < 0.001) reported higher levels of loneliness compared to people with psychosis. These differences remained significant after adjustment for all psychological and social variables. Perceived discrimination and internalized stigma were also independently associated with loneliness and substantially contributed to a final explanatory model. The severity of loneliness varies between different mental health diagnostic groups. Both people with common mental disorders and personality disorders reported higher levels of loneliness than people with psychosis. Addressing perceived mental health discrimination and stigma may help to reduce loneliness
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