A feasibility study of the mass spectrometer instrumentation for the analysis of the Martian atmosphere Final report

Mass spectrometer instrumentation for analysis of Mars atmospher

Evaluation of the operating internal resistance, inductance, and capacitance of intact damped sine wave defibrillators

A method is developed for determining actual values of circuit elements in a damped sine wave (Lown waveform) defibrillator, solely from measurements of the output, using two or more power resistors and a storage oscilloscope. If a defibrillator containing capacitance, C, inductance, L, and internal resistance, Ri, is discharged into increasing 5- to 100-ohm resistive loads, R, it is shown for underdamped output waveforms that aˆ = Ri/2L + R/2L and cˆ = CRi + CR, where aˆ = /[t2 tan(t1/t2)], cˆ = 2 aˆ /[ 2 aˆ + (/t2)2], t1 = time from onset to peak, and t2 = time from onset to first zero crossing of the output waveform on the oscilloscope trace. Linear plots of aˆ vs. R are constructed for seven defibrillators, and values of Ri and L computed as intercept/slope and 1/(2 slope) respectively. C is given by the slope of a linear plot of cˆ vs. R. Delivered energy is accurately predicted as stored energy R/(Ri + R)

Religious discrimination and symbolism: a philosophical perspective

This report is the product of the Arts-and-Humanities Research Council’s Connected Communities programme. The specific project being undertaken at the University of Liverpool is entitled Philosophy of Religion and Religious Communities: Defining Beliefs and Symbols. The aim of the Liverpool project as a whole is to consider the contribution philosophy of religion can make to recent debates surrounding legal cases alleging religious discrimination. Its orienting question runs, ‘when, if ever, is it acceptable to prohibit the use of religious symbols?’. The present report scrutinises in detail the way in which Article 9 of the European Convention of Human Rights has been utilised in recent judgments concerning the uses of religious symbolism. It argues that since 1995, Strasbourg jurisprudence, followed, to some extent, by domestic jurisprudence, has displayed what we call ‘the practical turn’. This we analyse as the turn away from seeing actions solely in the light of the antecedent beliefs that they manifest to seeing actions and the practices that they compose in their own right alongside beliefs. The practical turn can, we consider, be given several slightly different detailed readings. One such is that it is the turn from consideration of high-level theoretical systems of belief (such as religions), to which actions and practices are considered subservient, to consideration of individual low-level practical beliefs on an equal footing with the actions that naturally flow from them

Temporal Stability and Precision of Ventricular Defibrillation Threshold Data

Over two-hundred measurements of the minimum damped sinusoidal current and energy for transchest electrical ventricular defibrillation (ventricular defibrillation threshold) were made to determine the stability and precision of threshold data in 15 pentobarbital-anesthetized dogs. Threshold was determined by repeated trials of fibrillation and defibrillation with successive shocks of diminishing current, each 19% less than that of the preceeding shock. The lowest shock intensity that defibrillated was defined as threshold. In three groups of five dogs each, threshold was measured at intervals of 60, 15, and 5 min. over periods of 8, 5, and 1 hr. respectively. Similar results were obtained for all groups. There was no significant change in mean threshold current with time. Due to a decrease in transchest impedance, threshold delivered energy decreased by 10% during the first hour of testing. The standard deviations for threshold peak current and delivered energy in a given animal were 11 and 22 percent of their respective mean values. Arterial blood pH, pc02, and p02 averaged 7.38, 34 mmHg, and 72 mmHg respectively. The rates of change of pH, pCO2 and p02 were not significantly different from zero. The data demonstrate that ventricular defibrillation threshold is a stable physiologic parameter which may be measured with reasonable precision

Dependence of Defibrillation Threshold Upon Extracellular/Intracellular K+ Concentrations

The effect of increasing extracellular potassium concentration (Ko) upon electrical ventricular defibrillation threshold was investigated in pentobarbital anesthetized dogs treated with intravenous potassium chloride. Defibrillation threshold fell during potassium intoxication. The percent decrease in defibrillation threshold was linearly related to the logarithm of Ko and to the potassium equilibrium potential, EK, calculated from measured extracellular and intracellular potassium concentrations of ventricular muscle. In dogs supported by left ventricular bypass in order to maintain the circulation during potassium intoxication, the values of Ko and EK required for spontaneous, K+ induced defibrillation (electrical defibrillation threshold = zero) were 16.6 mEq/L and -46 mV compared to the normal values of 3.9 mEq/L and -84 mV. Changes in defibrillation threshold related to changes in EK may be significant events in digitalis intoxication and in myocardial anoxia during prolonged fibrillation. Defibrillation of the heart is often discussed as a large scale analog of cardiac pacing. Termination of atrial or ventricular fibrillation by a strong electric shock, applied with paddle electrodes across the chest or directly to the heart, is assumed to be the result of stimulation of a diffuse mass of potentially excitable cells (1, 2). The mechanism of defibrillation is usually stated to be the consequent production of a simultaneously refractory state in the entirety of a critical mass of the fibrillating myocardium (3, 4)

Reductions in the dietary niche of southern sea otters (Enhydra lutris nereis) from the Holocene to the Anthropocene.

The sea otter (Enhydra lutris) is a marine mammal hunted to near extinction during the 1800s. Despite their well-known modern importance as a keystone species, we know little about historical sea otter ecology. Here, we characterize the ecological niche of ancient southern sea otters (E. lutris nereis) using δ13C analysis and δ15N analysis of bones recovered from archaeological sites spanning ~7,000 to 350 years before present (N = 112 individuals) at five regions along the coast of California. These data are compared with previously published data on modern animals (N = 165) and potential modern prey items. In addition, we analyze the δ15N of individual amino acids for 23 individuals to test for differences in sea otter trophic ecology through time. After correcting for tissue-specific and temporal isotopic effects, we employ nonparametric statistics and Bayesian niche models to quantify differences among ancient and modern animals. We find ancient otters occupied a larger isotopic niche than nearly all modern localities; likely reflecting broader habitat and prey use in prefur trade populations. In addition, ancient sea otters at the most southerly sites occupied an isotopic niche that was more than twice as large as ancient otters from northerly regions. This likely reflects greater invertebrate prey diversity in southern California relative to northern California. Thus, we suggest the potential dietary niche of sea otters in southern California could be larger than in central and northern California. At two sites, Año Nuevo and Monterey Bay, ancient otters had significantly higher δ15N values than modern populations. Amino acid δ15N data indicated this resulted from shifting baseline isotope values, rather than a change in sea otter trophic ecology. Our results help in better understanding the contemporary ecological role of sea otters and exemplify the strength of combing zooarchaeological and biological information to provide baseline data for conservation efforts