1,209 research outputs found
Extended moment arm anti-spin device
A device which corrects aerodynamic spin is provided in which a collapsible boom extends an aircraft moment arm and an anti-spin parachute force is exerted upon the end of the moment arm to correct intentional or inadvertent aerodynamic spin. This configuration effects spin recovery by means of a parachute whose required diameter decreases as an inverse function of the increasing length of the moment arm. The collapsible boom enables the parachute to avoid the aircraft wake without mechanical assistance, retracts to permit steep takeoff, and permits a parachute to correct spin while minimizing associated aerodynamic, structural and in-flight complications
Spin-tunnel investigation of a 1/25-scale model of the General Dynamics F-16XL airplane
A spin-tunnel investigation of the spin and recovery characteristics of a 1/25-scale model to the General Dynamics F-16XL aircraft was conducted in the Langley Spin Tunnel. Tests included erect and inverted spins at various symmetric and asymmetric loading conditions. The required size of an emergency spin-recovery parachute was determined
Low-speed aerodynamic characteristics of a 1/8-scale X-29A airplane model at high angles of attack and sideslip
A 1/8-scale model of the X-29A airplane was tested in the Ames 12-Foot Pressure Wind Tunnel at a Mach number of 0.20 and Reynolds numbers of 0.13 x 10 to the 6th power to 2.00 x 10 to the 6th power based on a fuselage forebody depth of 0.4 ft, For the test series presented herein, the angle of attack ranged from 40 deg. to 90 deg. and the angle of sideslip ranged from -10 deg. to 30 deg. for the erect attitude. Tests with the model inverted covered angles of attack from -40 deg. to -90 deg. and angles of sideslip from -30 deg. to 10 deg. Data were obtained for the basic design and for several forebody strakes. An alternate forebody design was also tested. The results provided information for selection of forebody strakes for compensation of Reynolds number effect on the 1/25-scale free-spinning model tested in the Langley Spin Tunnel
Nitric Oxide Production as an Indication of \u3ci\u3eMycobacterium Bovis \u3c/i\u3eInfection in White-Tailed Deer (\u3ci\u3eOdocoileus virginianus\u3c/i\u3e)
White-tailed deer ( Odocoileus virginianus ) are reservoirs for Mycobacterium bovis in northeast Michigan, USA. Production of nitric oxide (NO) by activated macrophages is a potent mechanism of mycobacterial killing. The capacity of macrophages to produce NO, however, varies among mammalian species. The objective of this study was to determine if mononuclear cells from white-tailed deer produce nitrite as an indication of NO production and, if so, is NO produced in response to stimulation with M. bovis antigens. Supernatants were harvested from adherent peripheral blood mononuclear cell (PBMC) cultures that had been stimulated with either Mannheimia haemolytica lipopolysaccharide (LPS) or media alone (i.e., no stimulation). Nitrite levels within M. haemolytica LPS-stimulated culture supernatants exceeded (P \u3c 0.05) those detected within supernatants from non-stimulated cultures as well as those detected within supernatants from cultures receiving an inhibitor of NO synthase in addition to M. haemolytica LPS. In response to stimulation with M. bovis antigens, nitrite production by PBMC from M. bovis -infected deer exceeded (P \u3c 0.05) the production by PBMC from non-infected deer. The response of PBMC from infected deer to M. bovis antigens exceeded (P \u3c 0.05) the response of parallel cultures from the same deer receiving no stimulation. The response of PBMC from M. bovis -infected deer to M. avium antigens did not differ from that of PBMC from M. bovis infected deer to no stimulation or from that of PBMC from non-infected deer to M. avium antigens. These findings indicate that adherent PBMC from white-tailed deer are capable of NO production and that mononuclear cells isolated from M. bovis -infected white-tailed deer produce NO in an antigen-specific recall response
Nitric Oxide Production as an Indication of \u3ci\u3eMycobacterium Bovis \u3c/i\u3eInfection in White-Tailed Deer (\u3ci\u3eOdocoileus virginianus\u3c/i\u3e)
White-tailed deer ( Odocoileus virginianus ) are reservoirs for Mycobacterium bovis in northeast Michigan, USA. Production of nitric oxide (NO) by activated macrophages is a potent mechanism of mycobacterial killing. The capacity of macrophages to produce NO, however, varies among mammalian species. The objective of this study was to determine if mononuclear cells from white-tailed deer produce nitrite as an indication of NO production and, if so, is NO produced in response to stimulation with M. bovis antigens. Supernatants were harvested from adherent peripheral blood mononuclear cell (PBMC) cultures that had been stimulated with either Mannheimia haemolytica lipopolysaccharide (LPS) or media alone (i.e., no stimulation). Nitrite levels within M. haemolytica LPS-stimulated culture supernatants exceeded (P \u3c 0.05) those detected within supernatants from non-stimulated cultures as well as those detected within supernatants from cultures receiving an inhibitor of NO synthase in addition to M. haemolytica LPS. In response to stimulation with M. bovis antigens, nitrite production by PBMC from M. bovis -infected deer exceeded (P \u3c 0.05) the production by PBMC from non-infected deer. The response of PBMC from infected deer to M. bovis antigens exceeded (P \u3c 0.05) the response of parallel cultures from the same deer receiving no stimulation. The response of PBMC from M. bovis -infected deer to M. avium antigens did not differ from that of PBMC from M. bovis infected deer to no stimulation or from that of PBMC from non-infected deer to M. avium antigens. These findings indicate that adherent PBMC from white-tailed deer are capable of NO production and that mononuclear cells isolated from M. bovis -infected white-tailed deer produce NO in an antigen-specific recall response
Diagnostic Implications of Antigen-Induced Gamma Interferon, Nitric Oxide, and Tumor Necrosis Factor Alpha Production by Peripheral Blood Mononuclear Cells from \u3ci\u3eMycobacterium bovis\u3c/i\u3e-Infected Cattle
Bovine tuberculosis in the United States has proven costly to cattle producers as well as to government regulatory agencies. While in vivo responsiveness to mycobacterial antigens is the current standard for the diagnosis of tuberculosis, in vitro assays are gaining acceptance, especially as ancillary or complementary tests. To evaluate in vitro indices of cellular sensitization, antigen-induced gamma interferon (IFN-γ), nitric oxide (NO), and tumor necrosis factor alpha (TNF-α) responses by blood mononuclear cells from Mycobacterium bovis-infected cattle were quantified and compared. Using an aerosol model of infection, two doses of each of two strains of M. bovis (95-1315 and HC-2045T) were used to induce a range of IFN-γ, NO, and TNF-α responses. Infection-specific increases in NO, but not in IFN-γ or TNF-α, were detected in nonstimulated cultures at 48 h, a finding that is indicative of nonspecific activation and spontaneous release of NO. The infective dose of M. bovis organisms also influenced responses. At 34 days postinfection, IFN-γ, NO, and TNF-α responses in antigen-stimulated cells from cattle receiving 105 CFU of M. bovis organisms were greater than responses of cells from cattle infected with 103 CFU of M. bovis organisms. The NO response, but not the IFN-γ and TNF-α responses, was influenced by infective strains of M. bovis. The TNF-α, NO, and IFN-γ responses followed similar kinetics, with strong positive associations among the three readouts. Overall, these findings indicate that NO and TNF-α, like IFN-γ, may prove useful as indices for the diagnosis of bovine tuberculosis
Interferometric Astrometry of Proxima Centauri and Barnard's Star Using Hubble Space Telescope Fine Guidance Sensor 3: Detection Limits for sub-Stellar Companions
We report on a sub-stellar companion search utilizing interferometric
fringe-tracking astrometry acquired with Fine Guidance Sensor 3 (FGS 3) on the
Hubble Space Telescope. Our targets were Proxima Centauri and Barnard's Star.
We obtain absolute parallax values for Proxima Cen pi_{abs} = 0.7687 arcsecond
and for Barnard's Star pi_{abs} = 0.5454 arcsecond.
Once low-amplitude instrumental systematic errors are identified and removed,
our companion detection sensitivity is less than or equal to one Jupiter mass
for periods longer than 60 days for Proxima Cen. Between the astrometry and the
radial velocity results we exclude all companions with M > 0.8M_{Jup} for the
range of periods 1 < P < 1000 days. For Barnard's Star our companion detection
sensitivity is less than or equal to one Jupiter mass for periods long er than
150 days. Our null results for Barnard's Star are consistent with those of
Gatewood (1995).Comment: 35 pages, 13 figures, to appear in August 1999 A
Photometry of Proxima Centauri and Barnard's Star Using HST Fine Guidance Sensor 3: A Search for Periodic Variations
We have observed Proxima Centauri and Barnard's Star with Hubble Space
Telescope Fine Guidance Sensor 3. Proxima Centauri exhibits small-amplitude,
periodic photometric variations. Once several sources of systematic photometric
error are corrected, we obtain 2 milli-magnitude internal photometric
precision. We identify two distinct behavior modes over the past four years:
higher amplitude, longer period; smaller amplitude, shorter period. Within the
errors one period (P ~ 83d) is twice the other. Barnard's Star shows very weak
evidence for periodicity on a timescale of approximately 130 days. If we
interpret these periodic phenomena as rotational modulation of star spots, we
identify three discrete spots on Proxima Cen and possibly one spot on Barnard's
Star. We find that the disturbances change significantly on time scales as
short as one rotation period.Comment: 39 pages, 17 figure
National Geodetic Satellite Program, Part II: Smithsonian Astrophysical Observatory
A sequence of advances in the determination of geodetic parameters presented by the Smithsonian Astrophysical Observatory are described. A Baker-Nunn photographic system was used in addition to a ruby-laser ranging system to obtain data for refinement of geodetic parameters. A summary of the data employed to: (1) derive coordinates for the locations of various tracking stations; and (2) determine the gravitational potential of the earth, is presented
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