1,266 research outputs found

    Coping with Stress: The Caulobacter Approach

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    Holiness and the Christian life in the theology of Martin Luther and John Calvin

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    https://place.asburyseminary.edu/ecommonsatsdissertations/1943/thumbnail.jp

    Time estimation in mechanical engineering design.

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    SIGLEAvailable from British Library Document Supply Centre-DSC:DX195730 / BLDSC - British Library Document Supply CentreGBUnited Kingdo

    Xp54 and related (DDX6-like) RNA helicases: roles in messenger RNP assembly, translation regulation and RNA degradation

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    The DEAD-box RNA helicase Xp54 is an integral component of the messenger ribonucleoprotein (mRNP) particles of Xenopus oocytes. In oocytes, several abundant proteins bind pre-mRNA transcripts to modulate nuclear export, RNA stability and translational fate. Of these, Xp54, the mRNA-masking protein FRGY2 and its activating protein kinase CK2α, bind to nascent transcripts on chromosome loops, whereas an Xp54-associated factor, RapA/B, binds to the mRNP complex in the cytoplasm. Over-expression, mutation and knockdown experiments indicate that Xp54 functions to change the conformation of mRNP complexes, displacing one subset of proteins to accommodate another. The sequence of Xp54 is highly conserved in a wide spectrum of organisms. Like Xp54, Drosophila Me31B and Caenorhabditis CGH-1 are required for proper meiotic development, apparently by regulating the translational activation of stored mRNPs and also for sorting certain mRNPs into germplasm-containing structures. Studies on yeast Dhh1 and mammalian rck/p54 have revealed a key role for these helicases in mRNA degradation and in earlier remodelling of mRNP for entry into translation, storage or decay pathways. The versatility of Xp54 and related helicases in modulating the metabolism of mRNAs at all stages of their lifetimes marks them out as key regulators of post-transcriptional gene expression

    Collegiate Assimilation and Current Quality of High School Friendships

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    Jablin’s (1982) organizational assimilation theory states that as individuals are assimilated into a new organization, new relationships are formed. The formation of new relationships means that less effort can be committed to maintaining past relationships. This study investigated whether a college student’s progression through the phases of organizational assimilation via- encounter, metamorphosis, and exit phases, were predictive of the current quality of high school friendships. The results demonstrated that an individual’s progression through each phase of assimilation was not predictive of past friendship quality

    J. Weston Walch Correspondence

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    Entries include brief and possibly correct biographical information, a letter typed on J. Weston Walch, Publisher, stationery with an illustration of his place of business in Portland, Maine, wherein he presents materials for the Maine Author Collection, and a typed letter from the Maine State Library on receipt of his debate series titles Complete Handbook on Free Trade and Complete Handbook on Recognition of Communist China
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