623 research outputs found

    Interprofessional Collaborator Curriculum

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    Background: Physicians are often expected to participate with teams of health professionals; however, postgraduate training infrequently includes interprofessional (IP) or team training. Purpose: This curriculum was developed to demonstrate the knowledge, skills and attitudes which lead to successful IP collaboration. Curriculum: During a four-week geriatrics rotation, medicine interns complete a fifty-minute, in-person, multimedia lecture to introduce the IP collaborator concept and the Canadian and American IP competency frameworks. The IP pocket card is demonstrated and interns complete a guided, team-meeting video observation exercise. Using a Survey Monkey, narrative reporting tool, interns analyze team competencies that they observe or initiate during geriatrics team meetings during the rotation. They report on two interactions. They complete a closing Survey Monkey questionnaire and have an in-person debriefing. Results: We will have quantitative and qualitative data on interns’ recognition of IP collaborator competencies. Conclusion: Recognition of IP collaborator competencies will provide a framework for improving health professional effectiveness for systems-based care. Relevance to IP education or practice: Disseminating IP competencies. Learning Objectives: 1. The audience will be able to describe a new strategy for teaching IP competencies to health professionals. 2. The audience will become aware of a new method for combining the Canadian and American IP competencies. Todd James, MD, FACP Assistant Professor of Clinical Medicine Indiana University School of Medicine, Geriatrics Faculty Office Building, Floor 2 720 Eskenazi Avenue Indianapolis, IN 46202 Phone: 317-880-6582 Fax: 317-880-0332 Email: [email protected]

    Posttransplant lymphoproliferative disorders in neuronal xenotransplanted macaques

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    Posttransplant lymphoproliferative disorders (PTLDs) are a heterogeneous group of lymphoid proliferations that occur in the setting of depressed T-cell function due to immunosuppressive therapy used following solid organ transplantation, hematopoietic stem cell transplantation, and also xenotransplantation. In the present study, 28 immunosuppressed parkinsonian Macaca fascicularis were intracerebrally injected with wild-type or CTLA4-Ig transgenic porcine xenografts to identify a suitable strategy to enable long-term cell survival, maturation, and differentiation. Nine of 28 (32%) immunosuppressed primates developed masses compatible with PTLD, located mainly in the gastrointestinal tract and/or nasal cavity. The masses were classified as monomorphic PTLD according to the World Health Organization classification. Immunohistochemistry and polymerase chain reaction (PCR) analyses revealed that the PTLDs were associated with macaca lymphocryptovirus as confirmed by double-labeling immunohistochemistry for CD20 and Epstein-Barr nuclear antigen 2 (EBNA-2), where the viral protein was located within the CD20+ neoplastic B cells. In sera from 3 distinct phases of the experimental life of the primates, testing by quantitative PCR revealed a progression of the viral load that paralleled the PTLD progression and no evidence of zoonotic transmission of porcine lymphotropic herpesvirus through xenoneuronal grafts. These data suggest that monitoring the variation of macaca lymphocryptovirus DNA in primates could be used as a possible early diagnostic tool for PTLD progression, allowing preemptive treatment such as immunosuppression therapy reduction

    Atomistic study on the pressure dependence of the melting point of NdFe12

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    We investigated, using molecular dynamics, how pressure affects the melting point of the recently theorised and epitaxially grown structure NdFe12. We modified Morse potentials using experimental constants and a genetic algorithm code, before running two-phase solid-liquid coexistence simulations of NdFe12 at various temperatures and pressures. The refitting of the Morse potentials allowed us to significantly improve the accuracy in predicting the melting temperature of the constituent elements

    Indeterminate-length quantum coding

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    The quantum analogues of classical variable-length codes are indeterminate-length quantum codes, in which codewords may exist in superpositions of different lengths. This paper explores some of their properties. The length observable for such codes is governed by a quantum version of the Kraft-McMillan inequality. Indeterminate-length quantum codes also provide an alternate approach to quantum data compression.Comment: 32 page

    On asymptotic continuity of functions of quantum states

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    A useful kind of continuity of quantum states functions in asymptotic regime is so-called asymptotic continuity. In this paper we provide general tools for checking if a function possesses this property. First we prove equivalence of asymptotic continuity with so-called it robustness under admixture. This allows us to show that relative entropy distance from a convex set including maximally mixed state is asymptotically continuous. Subsequently, we consider it arrowing - a way of building a new function out of a given one. The procedure originates from constructions of intrinsic information and entanglement of formation. We show that arrowing preserves asymptotic continuity for a class of functions (so-called subextensive ones). The result is illustrated by means of several examples.Comment: Minor corrections, version submitted for publicatio

    Parenting ‘gifted and talented’ children in urban areas: Parents' voices

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    This is the author's accepted manuscript. The final published article is available from the link below. Copyright © 2014 by SAGE Publications.International evidence demonstrates the importance of engaging parents in the education of their ‘high-potential’ children, yet limited research has focused on the involvement of parents from differing economic strata/backgrounds. The current study explored the dilemmas of parenting academically high-ability children from economically deprived urban areas in the UK. Data were gathered from a sample of parents whose children attended a university-based sustained intervention programme for designated ‘gifted’ pupils aged 12–16. Parental perceptions were sought in relation to (a) the usefulness/impact of the intervention programme, (b) parents’ aspirations for their children growing up in economically deprived urban areas and (c) parents’ views on the support provided by the extended family, peer groups and the wider community. The findings have significant implications for both policy and practice and, more specifically, for engaging parents in intervention programmes offered by universities and schools to children in order to increase their access to higher education and for enhancing their life chances
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