Quality of life in painful bone metastases: results from the Dutch bone metastasis study

This thesis focuses on several aspects of quality of life in patients with painful bone metastases, treated with palliative radiotherapy within the randomized Dutch Bone Metastasis Study.The detailed course of quality of life after treatment was studied, as was the relation between a pain response and quality of life. Also prognostic factors predicting a pain response, psychological distress, side-effects and survival were studied.LUMC / Geneeskunde Repositoriu

Through the Clock's Workings

A world first! The first remixed and remixable anthology of literature. This anthology of short stories is not some textual tome, frozen in time and space. It is alive, evolving organically in a constant state of flux. Why? Because each story is available under a Creative Commons licence, giving you rights to share and reuse the book as you see fit. So how do you use a remixable anthology? Simple. Step 1 - Read. Thumb your way through the pages at will. Find the stories you love, the ones you hate, the ones that could be better. Step 2 - Re/create. Each story is yours to share and to remix. Use only one paragraph or character or just make subtle changes. Change the genre, alter its formal or stylistic characteristics, or revise its message. Use as little or as much as you like - as long as it works. Step 3 - Share. Be part of a growing community of literature remixing. Post your remixes to the Remix My Lit website, remixmylit.com, and start sharing. The entire anthology can be remixed - the original stories, the remixes, and even the fonts. Through the Clock's Workings is Read&Write

Screening for psychological distress before radiotherapy for painful bone metastases may be useful to identify patients with high levels of distress

Biological, physical and clinical aspects of cancer treatment with ionising radiatio

Quality of life in painful bone metastases: results from the Dutch bone metastasis study

This thesis focuses on several aspects of quality of life in patients with painful bone metastases, treated with palliative radiotherapy within the randomized Dutch Bone Metastasis Study.The detailed course of quality of life after treatment was studied, as was the relation between a pain response and quality of life. Also prognostic factors predicting a pain response, psychological distress, side-effects and survival were studied.</p

Quality of life in painful bone metastases: results from the Dutch bone metastasis study

This thesis focuses on several aspects of quality of life in patients with painful bone metastases, treated with palliative radiotherapy within the randomized Dutch Bone Metastasis Study.The detailed course of quality of life after treatment was studied, as was the relation between a pain response and quality of life. Also prognostic factors predicting a pain response, psychological distress, side-effects and survival were studied.</p

Fatal Bilateral Pneumonitis After Locoregional Thoracic Chemoradiation in a Transplanted Patient Under Immunosuppressive Therapy

Biological, physical and clinical aspects of cancer treatment with ionising radiatio

Sparing the posterior surgical site when planning radiation therapy for thoracic metastatic spinal disease

Clinical Oncolog

A Patient-Specific Fracture Risk Assessment Tool for Femoral Bone Metastases: Using the Bone Strength (BOS) Score in Clinical Practice

Patients with femoral metastases are at risk of fracturing bones. It is important to prevent fractures in order to maintain mobility and quality of life. The BOne Strength (BOS) score is based on a computed tomography (CT)-based patient-specific finite element (FE) computer model that objectively calculates bone strength. In this pilot study, the added clinical value of the BOS score towards treatment-related decision making was assessed. In December 2019, the BOS score was implemented in four radiotherapy centers. The BOS scores and fracture risks of individual patients were calculated and returned to the physician to assist in treatment decisions. The physicians filled out a questionnaire, which was qualitatively analyzed. A follow-up to identify fractures and/or death was performed after six months. Until June 2021, 42 BOS scores were delivered (20 high, 9 moderate, and 13 low fracture risk). In 48%, the BOS score led to an adaptation of treatment plans. Physicians indicated that the BOS score provided objective insight into fracture risk, was reassuring for physicians and patients, and improved multidisciplinary discussions and shared decision making. In conclusion, the BOS score is an objective tool to assess fracture risk in femoral bone metastases and aids physicians and patients in making a more informed decision regarding the most appropriate treatment