82 research outputs found
Rumen and Liver Fluke Infections in Sheep and Goats in Northern and Southern Germany
Simple Summary Little is known about the distribution of rumen and liver flukes in sheep and goats in Germany or about the occurring rumen fluke species. These fluke infections can be detected by the parasite's eggs in the host animal's feces. Therefore, fecal samples from 223 sheep farms and 143 goat farms from northern and southern Germany were examined. The eggs of rumen flukes were detected on 2.2% of the samples, the eggs of common liver flukes on 2.7%, and the eggs of small liver flukes on 21.1% of the examined sheep farms. The rumen flukes were identified as the emerging species Calicophoron daubneyi. No rumen fluke eggs were detected on any of the goat farm samples, but common and small liver fluke eggs were detected in 5.6% and 7.0% of the goat herds, respectively. Differences in the geographical distribution of rumen and liver flukes between and within the two regions were identified. Rumen flukes were more frequently found in the north, while the two liver fluke species were more frequently found in the south of Germany. Sheep sharing the pasture with other ruminants were more likely to be infected with rumen flukes. Paramphistomidosis has recently been identified as an emerging parasitosis in Europe. This study estimated the prevalence of rumen flukes, Fasciola hepatica and Dicrocoelium dendriticum, in small ruminants in Germany and identified occurring rumen fluke species and potential predictors for fluke infections. Pooled fecal samples from 223 sheep farms and 143 goat farms in northern and southern Germany were examined by the sedimentation technique, and molecular species identification was performed on rumen-fluke-positive samples. In sheep, a flock prevalence of 2.2% was detected for rumen flukes. Calicophoron daubneyi was identified on four of five positive farms, while species identification failed in one flock. No rumen fluke eggs were detected in the examined goat herds. F. hepatica eggs were detected in 2.7% of the sheep flocks, while the herd prevalence was 5.6% in goats. Higher prevalence values of 21.1% (sheep) and 7.0% (goats) were observed for D. dendriticum. Mixed grazing with other ruminants and previously identified infections with rumen flukes and/or F. hepatica were identified as predictors for paramphistomidosis. The distribution of the three trematode species followed a geographical pattern associated with conditions favoring the relevant intermediate hosts. C. daubneyi is an established parasite in German sheep at a currently low prevalence
Improved study of a possible Theta+ production in the pp -> p K0 sigma+ reaction with the COSY-TOF spectrometer
The pp -> p K0 Sigma+ reaction was investigated with the TOF spectrometer at
COSY at 3.059 GeV/c incident beam momentum. The main objective was to clarify
whether or not a narrow exotic S = +1 resnance, the Theta+ pentaquark, is
populated at 1.53 GeV/c2 in the K0 p subsystem with a data sample of much
higher statistical significance compared to the previously reported data in
this channel. An analysis of these data does not confirm the existence of the
Theta+ pentaquark. This is expressed as an upper limit for the cross section
sigma (pp -> p K0 Sigma+) < 0.15 microbarn at the 95 percent confidence level.Comment: 11 pages, 5 figure
Systematic study of the pp -> pp omega reaction
A systematic study of the production of omega-mesons in
proton-proton-collisions was carried out in a kinematically complete experiment
at three excess energies(epsilon= 92, 128, 173MeV). Both protons were detected
using the large-acceptance COSY-TOF spectrometer at an external beam line at
the Cooler Synchrotron COSY at Forschungszentrum J\"ulich. The total cross
section, angular distributions of both omega-mesons and protons were measured
and presented in various reference frames such as the overall CMS, helicity and
Jackson frame. In addition, the orientation of the omega-spin and invariant
mass spectra were determined. We observe omega-production to take place
dominantly in Ss and Sp final states at epsilon = 92, 128 MeV and,
additionally, in Sd at epsilon= 173 MeV. No obvious indication of resonant
omega-production via N^*-resonances was found, as proton angular distributions
are almost isotropic and invariant mass spectra are compatible with phase space
distributions. A dominant role of ^3P_1 and ^1S_0 initial partial waves for
omega-production was concluded from the orientation of the decay plane of the
omega-meson. Although the Jackson angle distributions in the omega-p-Jackson
frame are anisotropic we argue that this is not an indication of a resonance
but rather a kinematical effect reflecting the anisotropy of the omega angular
distribution. The helicity angle distribution in the omega-p-helicity frame
shows an anisotropy which probably reflects effects of the omega angular
momenta in the final state; this observable may be, in addition to the
orientation of the omega decay plane, the most sensitive one to judge the
validity of theoretical descriptions of the production process.Comment: 17 pages, 16 figures, accepted for publication in EPJ
Production of Lambda and Sigma^0 hyperons in proton-proton collisions
This paper reports results on simultaneous measurements of the reaction
channels pp -> pK+\Lambda and pp -> pK+\Sigma^0 at excess energies of 204, 239,
and 284 MeV (\Lambda) and 127, 162, and 207 MeV (\Sigma^0). Total and
differential cross sections are given for both reactions. It is concluded from
the measured total cross sections that the high energy limit of the cross
section ratio is almost reached at an excess energy of only about 200 MeV. From
the differential distributions observed in the overall CMS as well as in the
Jackson and helicity frames, a significant contribution of interfering nucleon
resonances to the \Lambda production mechanism is concluded while resonant
\Sigma^0-production seems to be of lesser importance and takes place only
through specific partial waves of the entrance channel. The data also indicate
that kaon exchange plays a minor role in the case of \Lambda- but an important
role for \Sigma^0-production. Thus the peculiar energy dependence of the
\Lambda-to-\Sigma^0 cross section ratio appears in a new light as its
explanation requires more than mere differences between the p\Lambda and the
p\Sigma^0 final state interaction. The data provide a benchmark for theoretical
models already available or yet to come.Comment: 18 pages, 10 figures; accepted by The European Physical Journal A
(EPJ A
Interaction of an extended series of N-substituted di(2-picolyl)amine derivatives with copper(II). Synthetic, structural, magnetic and solution studies
Zusammenfassung für Entscheidungstragende
Die Zusammenfassung für Entscheidungstragende fasst die Inhalte des APCC Special Report „Landnutzung und Klimawandel in Österreich“ in komprimierter Form zusammen. Im Lichte des Zusammenhanges von Landnutzung, Klimawandel und gesellschaftlichem Wohlergehen werden die gegenwärtige Situation und zukünftige Entwicklungen in Österreich synoptisch beschrieben, wesentliche Optionen der Klimawandelanpassung und des Klimaschutzes dargestellt, deren Trade-offs und Synergien systematisch beleuchtet und zentrale Einsichten zur Umsetzung von Strategien zum Klimaschutz und der Klimawandelanpassung in Österreich zusammengefasst
Influence of N*-resonances on hyperon production in the channel pp->K+ Lambda p at 2.95, 3.20 and 3.30 GeV/c beam momentum
Hyperon production in the threshold region was studied in the reaction pp ->
K+Lp using the time-of-flight spectrometer COSY-TOF. Exclusive data, covering
the full phase-space, were taken at the three different beam momenta of
p_beam=2.95, 3.20 and 3.30 GeV/c, corresponding to excess energies of
epsilon=204, 285 and 316 MeV, respectively. Total cross-sections were deduced
for the three beam momenta to be 23.9+/-0.8 +/-2.0 ub, 28.4+/-1.3 +/-2.2 ub and
35.0+/-1.3 +/-3.0 ub. Differential observables including Dalitz plots were
obtained. The analysis of the Dalitz plots reveals a strong influence of the
N(1650)-resonance at p_beam=2.95 GeV/c, whereas for the higher momenta an
increasing relative contribution of the N(1710)- and/or of the
N(1720)-resonance was observed. In addition, the pL-final-state interaction
turned out to have a significant influence on the Dalitz plot distribution.Comment: accepted for publication at Physics Letters B; some minor text
changes were done; also the scale of the ordinates of figure 9 has been
changed
The pK0\Sigma+ final state in proton-proton collisions
This paper reports results from a study of the reaction pp->pK0\Sigma+ at
beam momenta of p_{beam} = 2950, 3059, and 3200 MeV/c (excess energies of
\epsilon= 126, 161, and 206 MeV). Total cross sections were determined for all
energies; a set of differential cross sections (Dalitz plots; invariant mass
spectra of all two-body subsystems; angular distributions of all final state
particles; distributions in helicity and Jackson frames) are presented for
\epsilon= 161 MeV. The total cross sections are proportional to the volume of
available three-body phase-space indicating that the transition matrix element
does not change significantly in this range of excess energies. It is concluded
from the differential data that the reaction proceeds dominantly via the
N(1710)P_{11} and/or N(1720)P_{13} resonance(s); N(1650)S_{11} and
\Delta(1600)P_{33} could also contribute.Comment: 15 pages, 10 figure
Deconvolution of complex G protein–coupled receptor signaling in live cells using dynamic mass redistribution measurements
Label-free biosensor technology based on dynamic mass redistribution (DMR) of cellular constituents promises to translate GPCR signaling into complex optical 'fingerprints' in real time in living cells. Here we present a strategy to map cellular mechanisms that define label-free responses, and we compare DMR technology with traditional second-messenger assays that are currently the state of the art in GPCR drug discovery. The holistic nature of DMR measurements enabled us to (i) probe GPCR functionality along all four G-protein signaling pathways, something presently beyond reach of most other assay platforms; (ii) dissect complex GPCR signaling patterns even in primary human cells with unprecedented accuracy; (iii) define heterotrimeric G proteins as triggers for the complex optical fingerprints; and (iv) disclose previously undetected features of GPCR behavior. Our results suggest that DMR technology will have a substantial impact on systems biology and systems pharmacology as well as for the discovery of drugs with novel mechanisms
Technische Zusammenfassung
Die Technische Zusammenfassung des APCC-Sonderberichts ″Landnutzung und Klimawandel in Österreich″ umfasst die Kernbotschaften der Kapitel 1–9. In ihr sind die Hauptaussagen zu den sozioökonomischen und klimatischen Treibern der Landnutzungsänderungen, zu den Auswirkungen von Landnutzung und -bewirtschaftung auf den Klimawandel, zu Minderungs- und Anpassungsoptionen im Kontext nachhaltiger Entwicklungsziele sowie zu Synergien, Zielkonflikten und Umsetzungsbarrieren von Klimamaßnahmen enthalten
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