Improved Sequence-Based Speculation Techniques for Implementing Memory Consistency

This work presents BMW, a new design for speculative implementations of memory consistency models in shared-memory multiprocessors. BMW obtains the same performance as prior proposals, but achieves this performance while avoiding several undesirable attributes of prior proposals: non-scalable structures, per-word valid bits in the data cache, modifications to the cache coherence protocol, and global arbitration. BMW uses a read and write bit per cache block and a standard invalidation-based cache coherence protocol to perform conflict detection while speculating. While speculating, stores to block not in the cache are placed into a coalescing store buffer until those misses return. Stores are written speculatively to the primary cache, and non-speculative state is maintained by cleaning dirty blocks before being written speculatively. Speculative blocks are invalidated on abort and marked as non-speculative on commit. This organization allows for fast, local commits while avoiding a non-scalable store queue

reports/881 Improved Sequence-based Speculation Techniques for Implementing Memory Consistency

This work presents BMW, a new design for speculative implementations of memory consistency models in shared-memory multiprocessors. BMW obtains the same performance as prior proposals, but achieves this performance while avoiding several undesirable attributes of prior proposals: non-scalable structures, per-word valid bits in the data cache, modifications to the cache coherence protocol, and global arbitration. BMW uses a read and write bit per cache block and a standard invalidation-based cache coherence protocol to perform conflict detection while speculating. While speculating, stores to block not in the cache are placed into a coalescing store buffer until those misses return. Stores are written speculatively to the primary cache, and non-speculative state is maintained by cleaning dirty blocks before being written speculatively. Speculative blocks are invalidated on abort and marked as non-speculative on commit. This organization allows for fast, local commits while avoiding a non-scalable store queue.

Up to 40 Gb/s Directly Modulated Laser Operating at Low Driving Current: Buried-Heterostructure Passive Feedback Laser (BH-PFL)

A directly modulated 1.55-m buriedheterostructure passive feedback laser exhibits a high modulation bandwidth of up to 34 GHz at moderate distributed-feedback (DFB) section currents between 20 and 60 mA. A very flat frequency response and a low alpha parameter have been demonstrated in the small signal modulation analysis. The device has open eyes at data rates of 25 and 40 Gb/s with reduced frequency chirp

Complement activation in experimental human malaria infection.

Contains fulltext : 52097.pdf (publisher's version ) (Closed access)The objective of this study was to investigate complement activation in uncomplicated, early phases of human malaria. Fifteen healthy volunteers were experimentally infected with Plasmodium falciparum malaria. Parasitemia and complement activation products were assessed. During blood stage parasitemia, volunteers showed a significant increase in soluble terminal complement complex (TCC) formation. After start of a curative regimen of artemether/lumefantrine, TCC further increased due to activation of both the classical and the alternative pathway. In-vitro studies confirmed activation of complement by parasite cultures. We thus detected an increase in complement activation in volunteers with experimentally induced malaria, even before parasitemia could be detected microscopically. This significant increase in complement activation occurred despite the possible control of TCC formation by complement regulatory proteins on erythrocytes and the extremely low levels of parasitemia. Treatment with artemether/lumefantrine was followed by classical and alternative pathway complement activation, without evidence for mannan-binding-lectin-mediated complement activation