Managing innovation in new product development: reviewing the performance of small and medium-sized enterprises

This paper reviews some aspects of the performance of small and medium-sized enterprises (SMEs) in responding to innovation and technological change when undertaking new product development. Focusing on the management of technology, it will consider the role of interaction and collective learning in building firm competencies. Through the development of new or existing technologies, firms aim to improve quality and cost-efficiency and to out-innovate their rivals. This is far from straightforward. Innovation is a complex process shaped not only by the firm's internal environment, but also by the interactions that occur between the firm and the many different actors and institutions that make up its external environment. Many SMEs appreciate the value of these interactions in promoting innovation. However, for those involved in innovative new product development they also bring with them associated risks such as, for example, a lower proportion of return on their technologies brought about by imitation by their rivals

学会抄録

Genome annotation. (XLSX 9 kb

Extreme precipitation in low mountain ranges in Central Europe: a comparative study between the Vosges and the Ore mountains

of the doctoral dissertation Extreme precipitation is related to flooding which is one of the most frequent natural hazards in Central Europe. Detailed understanding of extreme precipitation is the precondition for an efficient risk management and more precise projections of precipitation, which include uncertainties, especially at regional scale. The thesis focuses on extreme precipitation in the Ore Mountains (OM) and the Vosges Mountains (VG); two low mountain ranges in Central Europe experiencing orographic effect on precipitation. Based on state of the art about precipitation in OM and VG, a currently missing analysis of the temporal distribution of precipitation in VG was needed prior to the analysis of extremes. The original dataset of daily precipitation totals from 14 weather stations used in the initial study was extended to 168 stations covering a broader area of VG. The study of temporal distribution of precipitation during 1960-2013 led to a classification of stations: (i) mountainous stations with winter maxima and highest mean annual totals due to orographic enhancement of precipitation, (ii) stations on leeward slopes with two maxima (summer and winter), (iii) lee side stations with summer maxima and lowest mean annual totals due to rain shadow and more continental character, and..

Additional file 3: of The mitochondrial genome of Globodera ellingtonae is composed of two circles with segregated gene content and differential copy numbers

Alignment of the start of the shared sequence region between Globodera ellingtonae mtDNA-I and mtDNA-II. (PDF 105 kb

Innovation in healthcare manufacturing: transforming deployed medical care

This paper analyses the case for transforming deployed medical care through innovations in advanced manufacturing. Early-stage findings present expert views based on a cross-disciplinary roadmapping workshop, designed to steer requirements and identify desirable applications across a range of medical manufacturing engineering disciplines. This paper proposes how the adoption of Redistributed Manufacturing (RDM) has the potential to transform operational patient care pathways and supply chains in the context of military and emergency medicine. This encompasses the use of technologies such as additive manufacturing, bioprinting and other distributed approaches. This work is part of a national UK research programme and sets out the foundations for a position paper to guide future research and investment in both academia and practice

nGr.v1.0.iprscan.xml

inter pro scan as gzipped xm

nGr.v1.0.annotation+TE

GFF file with locations of all gene calls in the G. rostochiensis genome and all transposable element predictions

Additional file 19: Figure S9. of The genome of the yellow potato cyst nematode, Globodera rostochiensis, reveals insights into the basis of parasitism and virulence

Synteny clusters. Network representation of i-ADHoRe results. Scaffolds are represented as nodes (blue = G. rostochiensis, ochre = G. pallida) whose diameter is scaled by scaffold length and vertices are drawn between them if five or more anchorpoints (i.e. syntenic proteins, numbers on vertices indicate count of anchorpoints) have been found. The biggest cluster (dashed black line) is composed of 26 G. rostochiensis scaffolds (4.99 Mb) and 35 G. pallida scaffolds (5.54 Mb). Part of this cluster (grey dotted line) is shown in Fig. 6. (PDF 570 kb

nGr.v1.0.iprscan.xml

interproscan as ts

nGr.v1.0.blast2go.txt

blast2go annotation as gzipped text fil