The dynamic investigation of intrinsic vibration characteristics of a stranding machine by the finite element method

In response to the design problems of violent vibration and noise when a stranding machine is running at high speed, this project completed a motion simulation and vibration analysis based on the prototype FB-650C-2 bow-type stranding machine produced by Fuchuan Mechanical and Electrical Technology Co. The modal analysis was carried out in ANSYS to obtain the first eight orders of inherent frequencies and vibration patterns, combined with excitation force analysis to verify whether the rotating parts could avoid the resonant frequency when operating. Harmonic response analysis was carried out based on the modal state to calculate the steady-state forced vibration of the structure, and the variation curve of response value (usual deformation) with frequency and the cloud diagrams of stress distribution of each component at the rotation frequency were obtained. Suggestions for improving vibration and reducing noise were made based on the experimental and analytical results

Tirofiban for Stroke without Large or Medium-Sized Vessel Occlusion

The effects of the glycoprotein IIb/IIIa receptor inhibitor tirofiban in patients with acute ischemic stroke but who have no evidence of complete occlusion of large or medium-sized vessels have not been extensively studied. In a multicenter trial in China, we enrolled patients with ischemic stroke without occlusion of large or medium-sized vessels and with a National Institutes of Health Stroke Scale score of 5 or more and at least one moderately to severely weak limb. Eligible patients had any of four clinical presentations: ineligible for thrombolysis or thrombectomy and within 24 hours after the patient was last known to be well; progression of stroke symptoms 24 to 96 hours after onset; early neurologic deterioration after thrombolysis; or thrombolysis with no improvement at 4 to 24 hours. Patients were assigned to receive intravenous tirofiban (plus oral placebo) or oral aspirin (100 mg per day, plus intravenous placebo) for 2 days; all patients then received oral aspirin until day 90. The primary efficacy end point was an excellent outcome, defined as a score of 0 or 1 on the modified Rankin scale (range, 0 [no symptoms] to 6 [death]) at 90 days. Secondary end points included functional independence at 90 days and a quality-of-life score. The primary safety end points were death and symptomatic intracranial hemorrhage. A total of 606 patients were assigned to the tirofiban group and 571 to the aspirin group. Most patients had small infarctions that were presumed to be atherosclerotic. The percentage of patients with a score of 0 or 1 on the modified Rankin scale at 90 days was 29.1% with tirofiban and 22.2% with aspirin (adjusted risk ratio, 1.26; 95% confidence interval, 1.04 to 1.53, P = 0.02). Results for secondary end points were generally not consistent with the results of the primary analysis. Mortality was similar in the two groups. The incidence of symptomatic intracranial hemorrhage was 1.0% in the tirofiban group and 0% in the aspirin group. In this trial involving heterogeneous groups of patients with stroke of recent onset or progression of stroke symptoms and nonoccluded large and medium-sized cerebral vessels, intravenous tirofiban was associated with a greater likelihood of an excellent outcome than low-dose aspirin. Incidences of intracranial hemorrhages were low but slightly higher with tirofiban

Methylprednisolone as Adjunct to Endovascular Thrombectomy for Large-Vessel Occlusion Stroke

Importance It is uncertain whether intravenous methylprednisolone improves outcomes for patients with acute ischemic stroke due to large-vessel occlusion (LVO) undergoing endovascular thrombectomy. Objective To assess the efficacy and adverse events of adjunctive intravenous low-dose methylprednisolone to endovascular thrombectomy for acute ischemic stroke secondary to LVO. Design, Setting, and Participants This investigator-initiated, randomized, double-blind, placebo-controlled trial was implemented at 82 hospitals in China, enrolling 1680 patients with stroke and proximal intracranial LVO presenting within 24 hours of time last known to be well. Recruitment took place between February 9, 2022, and June 30, 2023, with a final follow-up on September 30, 2023.InterventionsEligible patients were randomly assigned to intravenous methylprednisolone (n = 839) at 2 mg/kg/d or placebo (n = 841) for 3 days adjunctive to endovascular thrombectomy. Main Outcomes and Measures The primary efficacy outcome was disability level at 90 days as measured by the overall distribution of the modified Rankin Scale scores (range, 0 [no symptoms] to 6 [death]). The primary safety outcomes included mortality at 90 days and the incidence of symptomatic intracranial hemorrhage within 48 hours. Results Among 1680 patients randomized (median age, 69 years; 727 female [43.3%]), 1673 (99.6%) completed the trial. The median 90-day modified Rankin Scale score was 3 (IQR, 1-5) in the methylprednisolone group vs 3 (IQR, 1-6) in the placebo group (adjusted generalized odds ratio for a lower level of disability, 1.10 [95% CI, 0.96-1.25]; P = .17). In the methylprednisolone group, there was a lower mortality rate (23.2% vs 28.5%; adjusted risk ratio, 0.84 [95% CI, 0.71-0.98]; P = .03) and a lower rate of symptomatic intracranial hemorrhage (8.6% vs 11.7%; adjusted risk ratio, 0.74 [95% CI, 0.55-0.99]; P = .04) compared with placebo. Conclusions and Relevance Among patients with acute ischemic stroke due to LVO undergoing endovascular thrombectomy, adjunctive methylprednisolone added to endovascular thrombectomy did not significantly improve the degree of overall disability.Trial RegistrationChiCTR.org.cn Identifier: ChiCTR210005172

The Ninth Visual Object Tracking VOT2021 Challenge Results

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Analysis of the influences of bracket and force system in different directions on the moment to force ratio by finite element method

Abstract The human teeth face a variety of ways to move during orthodontic treatment. The types of orthodontic tooth movements have linked to the moment to force (M/F) ratio. This paper aims to determine the precise M/F ratios that generate different types of movements for the models with and without bracket, and the M/F ratios are compared between the force systems applied in buccal-lingual and distal-mesial direction for the mandible canine by using finite element method (FEM). A segment of mandible canine obtained from autopsy had been scanned with microcomputed tomography, and two finite element models with and without brackets were established. Each canine model was subjected to a force of 100 cN and varied M/F ratios from 0 ~ 12 in buccal-lingual and distal-mesial directions. We find that the model with a bracket required larger M/F ratio compared to the model without a bracket for the same tooth movement. For the different directions, the value of M/F ratio is larger in the buccal-lingual than in the distal-mesial direction. The geometry of the tooth and the PDL are gained from a regular patient. Therefore, the results are applicable to any canine, and the precise M/F values provide a theoretical basis for the orthodontist design optimal force system

Bending Angle Prediction Model Based on BPNN-Spline in Air Bending Springback Process

In order to rapidly and accurately predict the springback bending angle in V-die air bending process, a springback bending angle prediction model on the combination of error back propagation neural network and spline function (BPNN-Spline) is presented in this study. An orthogonal experimental sample set for training BPNN-Spline is obtained by finite element simulation. Through the analysis of network structure, the BPNN-Spline black box function of bending angle prediction is established, and the advantage of BPNN-Spline is discussed in comparison with traditional BPNN. The results show a close agreement with simulated and experimental results by application examples, which means that the BPNN-Spline model in this study has higher prediction accuracy and better applicable ability. Therefore, it could be adopted in a numerical control bending machine system