Blind Image Super-resolution with Rich Texture-Aware Codebooks

Blind super-resolution (BSR) methods based on high-resolution (HR) reconstruction codebooks have achieved promising results in recent years. However, we find that a codebook based on HR reconstruction may not effectively capture the complex correlations between low-resolution (LR) and HR images. In detail, multiple HR images may produce similar LR versions due to complex blind degradations, causing the HR-dependent only codebooks having limited texture diversity when faced with confusing LR inputs. To alleviate this problem, we propose the Rich Texture-aware Codebook-based Network (RTCNet), which consists of the Degradation-robust Texture Prior Module (DTPM) and the Patch-aware Texture Prior Module (PTPM). DTPM effectively mines the cross-resolution correlation of textures between LR and HR images by exploiting the cross-resolution correspondence of textures. PTPM uses patch-wise semantic pre-training to correct the misperception of texture similarity in the high-level semantic regularization. By taking advantage of this, RTCNet effectively gets rid of the misalignment of confusing textures between HR and LR in the BSR scenarios. Experiments show that RTCNet outperforms state-of-the-art methods on various benchmarks by up to 0.16 ~ 0.46dB

Triply charmed baryons mass decomposition from lattice QCD

We present the first lattice QCD calculation about the mass decomposition of triply charmed baryons with $J^{P}$ as $\frac{3}{2}^{+}$ and $\frac{3}{2}^{-}$. The quark mass term $\langle H_{M} \rangle$ contributes about 66\% to the mass of $\frac{3}{2}^+$ state, which is slightly lower than that of the meson system with the same valence charm quark. Furthermore, based on our results, the total contribution of sea quarks, the gluons and the QCD anomaly accounts for about a quarter of the mass of these two triply charmed baryons. The mass difference of $\frac{3}{2}^+$ and $\frac{3}{2}^-$ states is mainly from the quark energy $\langle H_{E} \rangle$ of the QCD energy-momentum tensor. For comparison, the mass splitting is also calculated under the framework of the constituent quark model.Comment: 7 page, 14 figure

Coniferous Canopy BRF Simulation Based on 3-D Realistic Scene

It is difficulties for the computer simulation method to study radiation regime at large-scale. Simplified coniferous model was investigate d in the present study. It makes the computer simulation methods such as L-systems and radiosity-graphics combined method (RGM) more powerf ul in remote sensing of heterogeneous coniferous forests over a large -scale region. L-systems is applied to render 3-D coniferous forest scenarios: and RGM model was used to calculate BRF (bidirectional refle ctance factor) in visible and near-infrared regions. Results in this study show that in most cases both agreed well. Meanwhiie at a tree and forest level. the results are also good

Antihyperglycemic and antihyperlipidemic action of cinnamaldehyde in C57blks/j Db/db mice

AbstractObjectiveTo investigate the effects of cinnamaldehyde (CA), an active and major compound in cinnamon, on glucose metabolism and insulin resistance in C57BLKS/J db/db mice.MethodsSixteen male C57BLKS db/db mice were randomly divided into control and CA treatment groups. CA was given (20 mg · kg−1 · day−1, p. o.) for 4 weeks. Pure water was given to control and db/+ mice. Subsequently, the levels of fasting blood glucose (FBG), fasting serum insulin, triglyeride, cholesterol, low-density lipoprotein -cholesterol (LDL-C), high-density lipoprotein-cholesterol (HDL-C), and free fatty acids (FFA), as well as the mRNA content of adiponectin and tumor necrosis factor (TNF)-α in adipose tissue, glucose transporter type 4 (GLUT-4) in skeletal muscle, and protein expressions of Akt, phospho-Akt (Thr308), AMPKα, phospho-AMPKα (Thr172) in skeletal muscle were measured.Results1) CA decreased serum levels of FBG and insulin as well as body weight in db/db mice; 2) CA increased serum HDL-C levels; 3) CA significantly decreased the mRNA expression of TNF-α in adipose tissue and upregulated mRNA expression of GLUT-4 in skeletal muscle; 4) protein expression of p-Akt was increased in CA-treated mice, but Akt, AMPKα and p-AMPKα showed no change.ConclusionCA has antihyperglycemic and antihyperlipidemic actions in db/db mice and could be useful in the treatment of type-2 diabetes

Study of higher-order harmonics of complex ac susceptibility in YB2C3O7−δYB_2C_3O_{7-\delta} thin films by the mutual inductive method

We have applied the mutual inductive method to study higher-order harmonics of complex ac susceptibility $\chi_n=\chi'_n-i\chi"_n$ for $$YB_2C_3O_{7-\delta}$thin films as function of the temperature and the applied field. The experimental results were compared with analytical and numerical results obtained from the Ishida-Mazaki model and the solution of the integral equation for the current density, respectively. Both models allow us to reproduced the main experimental features, however, as$n$increases the numerical model shows notable discrepancies. This failure can be attributed to the current-voltage characteristics. Also this investigation yields the activation energy$U_c$and the critical current density$J_c$ for two samples both at T=0.Comment: 8 pages, 3 figure

Enhanced Delivery of Rituximab Into Brain and Lymph Nodes Using Timed-Release Nanocapsules in Non-Human Primates.

Tumor metastasis into the central nervous system (CNS) and lymph nodes (LNs) is a major obstacle for effective therapies. Therapeutic monoclonal antibodies (mAb) have revolutionized tumor treatment; however, their efficacy for treating metastatic tumors-particularly, CNS and LN metastases-is poor due to inefficient penetration into the CNS and LNs following intravenous injection. We recently reported an effective delivery of mAb to the CNS by encapsulating the anti-CD20 mAb rituximab (RTX) within a thin shell of polymer that contains the analogs of choline and acetylcholine receptors. This encapsulated RTX, denoted as n-RTX, eliminated lymphoma cells systemically in a xenografted humanized mouse model using an immunodeficient mouse as a recipient of human hematopoietic stem/progenitor cells and fetal thymus more effectively than native RTX; importantly, n-RTX showed notable anti-tumor effect on CNS metastases which is unable to show by native RTX. As an important step toward future clinical translation of this technology, we further analyzed the properties of n-RTX in immunocompetent animals, rats, and non-human primates (NHPs). Our results show that a single intravenous injection of n-RTX resulted in 10-fold greater levels in the CNS and 2-3-fold greater levels in the LNs of RTX, respectively, than the injection of native RTX in both rats and NHPs. In addition, we demonstrate the enhanced delivery and efficient B-cell depletion in lymphoid organs of NHPs with n-RTX. Moreover, detailed hematological analysis and liver enzyme activity tests indicate n-RTX treatment is safe in NHPs. As this nanocapsule platform can be universally applied to other therapeutic mAbs, it holds great promise for extending mAb therapy to poorly accessible body compartments

Sustained delivery and molecular targeting of a therapeutic monoclonal antibody to metastases in the central nervous system of mice.

Approximately 15-40% of all cancers develop metastases in the central nervous system (CNS), yet few therapeutic options exist to treat them. Cancer therapies based on monoclonal antibodies are widely successful, yet have limited efficacy against CNS metastases, owing to the low levels of the drug reaching the tumour site. Here, we show that the encapsulation of rituximab within a crosslinked zwitterionic polymer layer leads to the sustained release of rituximab as the crosslinkers are gradually hydrolysed, enhancing the CNS levels of the antibody by approximately tenfold with respect to the administration of naked rituximab. When the nanocapsules were functionalized with CXCL13-the ligand for the chemokine receptor CXCR5, which is frequently found on B-cell lymphoma-a single dose led to improved control of CXCR5-expressing metastases in a murine xenograft model of non-Hodgkin lymphoma, and eliminated lymphoma in a xenografted humanized bone marrow-liver-thymus mouse model. Encapsulation and molecular targeting of therapeutic antibodies could become an option for the treatment of cancers with CNS metastases

Visual Reconstruction and Feature Analysis of the Three-Dimensional Surface of Earthworm

This paper demonstrates a method for visual reconstruction and feature analysis of the three-dimensional surface of earthworm in CATIA (Computer Aided Three Dimensional Interactive Application) and IDL (Interactive Data Language). The earthworm, with a relatively simple surface morphology and good capability in reducing soil adhesion and resistance, was selected to study the feasible methods in the visual reconstruction and feature analysis of the three-dimensional surface of living things. The digital measurements of surfaces of the earthworm were carried out using a three-dimensional laser scanner. Point clouds, the scanning digital data of the surface of the earthworm, were processed by screening unwanted data, reconstructing surface and analysing feature in CATIA. In order to get more detail information about the point clouds, IDL, which integrates a powerful, array-oriented language with numerous mathematical analysis and graphical display techniques, was adopted for the visual reconstruction and feature analysis of three- dimensional surface of the earthworm. Importing of point clouds and reconstruction of the surface of earthworm were conducted in CATIA. Analysis feature of the scanning data and reconstructing surface were carried out in IDL, which provides a high level of flexibility to access, analyse and visualize the data using different methods. Polynomial regression equation of the surface of earthworm in the longitudinal plane was derived. In addition, point clouds were more easily displayed and analysed by resizing, rotating and zooming in IDL. Methods and results presented in this paper prove to be potentially useful for analyzing the feature of biological prototype, optimizing the mathematical model and affording deformable physical model to bionic engineering, those works would have great implications to the research of biological coupling theory and technological creation in bionic engineering. Keywords: Visual Reconstruction; Feature Analysis; Three-Dimensional Surface; Earthworm; CATIA; ID