Examining the effect of an environmental social marketing intervention among university employees

This is an Accepted Manuscript of an article published by Taylor & Francis in Studies in Higher Education on 31 Mar 2017, available online: https://www.tandfonline.com/doi/full/10.1080/03075079.2017.130964

Low-Power Redundant-Transition-Free TSPC Dual-Edge-Triggering Flip-Flop Using Single-Transistor-Clocked Buffer

In the modern graphics processing unit (GPU)/artificial intelligence (AI) era, flip-flop (FF) has become one of the most power-hungry blocks in processors. To address this issue, a novel single-phase-clock dual-edge-triggering (DET) FF using a single-transistor-clocked (STC) buffer (STCB) is proposed. The STCB uses a single-clocked transistor in the data sampling path, which completely removes clock redundant transitions (RTs) and internal RTs that exist in other DET designs. Verified by post-layout simulations in 22 nm fully depleted silicon on insulator (FD-SOI) CMOS, when operating at 10% switching activity, the proposed STC-DET outperforms prior state-of-the-art low-power DET in power consumption by 14% and 9.5%, at 0.4 and 0.8 V, respectively. It also achieves the lowest power-delay-product (PDP) among the DETs

Testing earthquake links in Mexico from 1978 to the 2017 M = 8.1 Chiapas and M = 7.1 Puebla Shocks

The M = 8.1 Chiapas and the M = 7.1 Puebla earthquakes occurred in the bending part of the subducting Cocos plate 11 days and ~600 km apart, a range that puts them well outside the typical aftershock zone. We find this to be a relatively common occurrence in Mexico, with 14% of M > 7.0 earthquakes since 1900 striking more than 300 km apart and within a 2 week interval, not different from a randomized catalog. We calculate the triggering potential caused by crustal stress redistribution from large subduction earthquakes over the last 40 years. There is no evidence that static stress transfer or dynamic triggering from the 8 September Chiapas earthquake promoted the 19 September earthquake. Both recent earthquakes were promoted by past thrust events instead, including delayed afterslip from the 2012 M = 7.5 Oaxaca earthquake. A repeated pattern of shallow thrust events promoting deep intraslab earthquakes is observed over the past 40 years

Atypical haemolytic uraemic syndrome presenting initially as suspected meningococcal disease: a case report

<p>Abstract</p> <p>Background</p> <p>Haemolytic uraemic syndrome (HUS) is the most common cause of acute renal failure in children and is usually linked with Escherichia coli O157 infection. With a fatality rate of around 5%, some reports have associated antibiotic treatment with a worsening prognosis.</p> <p>Case Presentation</p> <p>We describe a female infant patient, initially treated for suspected meningococcal septicaemia, who went on to develop renal complications and thrombocytopenia characteristic of HUS. A subsequent positive stool sample for <it>E. coli </it>O157 confirmed HUS as an appropriate diagnosis, although there was no evidence of diarrhoea or vomiting throughout the course of her management.</p> <p>Conclusion</p> <p>The urgency of early recognition and treatment for suspected meningococcal disease in very young children while entirely appropriate can initially divert attention from other serious conditions. Evidence of infection with <it>E. coli </it>O157 infection in this case also highlights what can be a blurred distinction between atypical (non-diarrhoeal) HUS from classical HUS of infective origin.</p

Ribosome recycling, diffusion, and mRNA loop formation in translational regulation

We explore and quantify the physical and biochemical mechanisms that may be relevant in the regulation of translation. After elongation and detachment from the 3' termination site of mRNA, parts of the ribosome machinery can diffuse back to the initiation site, especially if it is held nearby, enhancing overall translation rates. The elongation steps of the mRNA-bound ribosomes are modeled using exact and asymptotic results of the totally asymmetric exclusion process (TASEP).Since the ribosome injection rates of the TASEP depend on the local concentrations at the initiation site, a source of ribosomes emanating from the termination end can feed back to the initiation site, leading to a self-consistent set of equations for the steady-state ribosome throughput. Additional mRNA binding factors can also promote loop formation, or cyclization, bringing the initiation and termination sites into close proximity. The probability distribution of the distance between the initiation and termination sites is described using simple noninteracting polymer models. We find that the initiation, or initial ribosome adsorption binding required for maximal throughput can vary dramatically depending on certain values of the bulk ribosome concentration and diffusion constant. If cooperative interactions among the loop-promoting proteins and the initiation/termination sites are considered, the throughput can be further regulated in a nonmonotonic manner. Potential experiments to test the hypothesized physical mechanisms are discussed.Comment: 21 pp, 11 .eps figs, realigned figures and magin