Hydrostatic sea level changes

Inverted barometer effects and steric changes effects on hydrostatic response of ocea

A Process-Oriented Architecture for Complex System Modelling

A fine-grained massively-parallel process-oriented model of platelets (potentially artificial) within a blood vessel is presented. This is a CSP inspired design, expressed and implemented using the occam-pi language. It is part of the TUNA pilot study on nanite assemblers at the universities of York, Surrey and Kent. The aim for this model is to engineer emergent behaviour from the platelets, such that they respond to a wound in the blood vessel wall in a way similar to that found in the human body -- i.e. the formation of clots to stem blood flow from the wound and facilitate healing. An architecture for a three dimensional model (relying strongly on the dynamic and mobile capabilities of occam-pi) is given, along with mechanisms for visualisation and interaction. The biological accuracy of the current model is very approximate. However, its process-oriented nature enables simple refinement (through the addition of processes modelling different stimulants/inhibitors of the clotting reaction, different platelet types and other participating organelles) to greater and greater realism. Even with the current system, simple experiments are possible and have scientific interest (e.g. the effect of platelet density on the success of the clotting mechanism in stemming blood flow: too high or too low and the process fails). General principles for the design of large and complex system models are drawn. The described case study runs to millions of processes engaged in ever-changing communication topologies. It is free from deadlock, livelock, race hazards and starvation em by design, employing a small set of synchronisation patterns for which we have proven safety theorems

Application of the Trend Filtering Algorithm on the MACHO Database

Due to the strong effect of systematics/trends in variable star observations, we employ the Trend Filtering Algorithm (TFA) on a subset of the MACHO database and search for variable stars. TFA has been applied successfully in planetary transit searches, where weak, short-lasting periodic dimmings are sought in the presence of noise and various systematics (due to, e.g., imperfect flat fielding, crowding, etc). These latter effects introduce colored noise in the photometric time series that can lead to a complete miss of the signal. By using a large number of available photometric time series of a given field, TFA utilizes the fact that the same types of systematics appear in several/many time series of the same field. As a result, we fit each target time series by a (least-square-sense) optimum linear combination of templates and frequency-analyze the residuals. Once a signal is found, we reconstruct the signal by employing the full model, including the signal, systematics and noise. We apply TFA on the brightest ~5300 objects from subsets of each of the MACHO Large Magellanic Cloud fields #1 and #79. We find that the Fourier frequency analysis performed on the original data detect some 60% of the objects as trend-dominated. This figure decreases essentially to zero after using TFA. Altogether, We detect 387 variables in the two fields, 183 of which would have remained undetected without using TFA. Where possible, we give preliminary classification of the variables found.Comment: 12 pages, 15 figures, 3 tables with online material; to appear in Astronomy and Astrophysic

Large angle Beamstrahlung as a beam-beam monitoring tool

A novel method to measure the beam-beam interaction in e+e- colliders is presented.Comment: 17 pages, four figures, to be published in Nuclear Instruments and Method

A robust design methodology suitable for application to one-off products

Robust design is an activity of fundamental importance when designing large, complex, one-off engineering products. Work is described which is concerned with the application of the theory of design of experiments and stochastic optimization methods to explore and optimize at the concept design stage. The discussion begins with a description of state-of-the-art stochastic techniques and their application to robust design. The content then focuses on a generic methodology which is capable of manipulating design algorithms that can be used to describe a design concept. An example is presented, demonstrating the use of the system for the robust design of a catamaran with respect to seakeeping

Radiation trapping in coherent media

We show that the effective decay rate of Zeeman coherence, generated in a Rb87 vapor by linearly polarized laser light, increases significantly with the atomic density. We explain this phenomenon as the result of radiation trapping. Our study shows that radiation trapping must be taken into account to fully understand many electromagnetically induced transparency experiments with optically thick media

The design and investigation of the self-assembly of dimers with two nematic phases

A series of non-symmetric dimers were synthesised containing either cyanobiphenyl or difluoroterphenyl moieties on one side and a range of long, short, bent, polar or apolar mesogens on the other side of the molecules. The dielectric anisotropy of the mesogens was varied systematically. The systems were characterised by differential scanning calorimetry (DSC), optical polarizing microscopy (OPM) and detailed X-ray diffraction (XRD) studies, both in the nematic and the Nx phase. The results are compared and structure properties relationships are discussed. A model for the assembly in the Nx phase is developed discussing Ntb structures, coaxial helices, swiss roll structures and chiral domain formation

Trains, tails and loops of partially adsorbed semi-flexible filaments

Polymer adsorption is a fundamental problem in statistical mechanics that has direct relevance to diverse disciplines ranging from biological lubrication to stability of colloidal suspensions. We combine experiments with computer simulations to investigate depletion induced adsorption of semi-flexible polymers onto a hard-wall. Three dimensional filament configurations of partially adsorbed F-actin polymers are visualized with total internal reflection fluorescence microscopy. This information is used to determine the location of the adsorption/desorption transition and extract the statistics of trains, tails and loops of partially adsorbed filament configurations. In contrast to long flexible filaments which primarily desorb by the formation of loops, the desorption of stiff, finite-sized filaments is largely driven by fluctuating filament tails. Simulations quantitatively reproduce our experimental data and allow us to extract universal laws that explain scaling of the adsorption-desorption transition with relevant microscopic parameters. Our results demonstrate how the adhesion strength, filament stiffness, length, as well as the configurational space accessible to the desorbed filament can be used to design the characteristics of filament adsorption and thus engineer properties of composite biopolymeric materials

The stabilisation of the Nx phase in mixtures

The phase behaviour of mixtures between two symmetric dimers, CBC9CB and the ether-linked analogue CBOC9OCB was investigated by Polarizing Optical Microscopy (POM), Differential Scanning Calorimetry (DSC) and X-Ray Diffraction (XRD) studies. The dimeric constituents are fully miscible and the construction of a temperature-composition phase diagram reveals a surprising amplification of the stability of the Nx phase in compositions of up to 37 wt% of CBOC9OCB in CBC9CB. The origin for this enhancement of stability is discussed and an explanation based on chiral recognition is developed