500 research outputs found

    The Tilted Playing Field

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    A Scalable Approach to Processing Large XML Data Volumes

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    A Turning Point in Aviation Training: The AQP Mandates Crew Resource Management and Line Operational Simulations

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    Crew Resource Management (CRM) and Line Oriented Flight Training (LOFT) have not been mandatory elements of air carrier flight crew training. Additionally, Full-Flight Simulation and Flight Training Devices (FTDs) have been tools utilized to various degrees by the different air carrier training departments. Each air carrier\u27s training program has traditionally been approved by its Federal Aviation Administration (FAA) Principal Operations Inspector (POI). The Advanced Qualification Program (AQP) is an alternative method of training air carrier flight crewmembers and will be a voluntary program applicable to airline certificate holders under the Code of Federal Regulations Section 14 (14 CFR--encompasses aeronautics and space) Parts 121 and 135. The FAA has facilitated the implementation of AQPs with the issuance of a Special Federal Aviation Regulation (SFAR 58), rather than rewriting the numerous Federal Aviation Regulations (FARs) which detail air carrier training. Additionally, an Air Carrier Training Branch (AFS-210) has been established to administer AQPs, with quality control being developed by a human factors specialist. Mandatory CRM training and the utilization of Line Operational Simulations (LOS--a rechristening of LOFT) are key elements of the AQP curriculum for flight crewmembers. As AQPs are approved, increased utilization of FTDs may augment and optimize Full-Flight Simulation. ... it is anticipated that AQP will become standard practice in the future for FAR Parts 121 and 135 operators (Longridge and Boothe, 1991)

    On the Untapped Value of e-HRM: A Literature Review

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    The “war for talent” is still on. Annually conducted surveys have indicated for years that one third of all organizations are unable to fill vacant job positions with suitable candidates. Responding to these and other challenges, human resource management (HRM) is expected to transform itself. General opinion holds that the HRM transformation has just begun and that the potential of IT in HRM is not yet fully exploited. Examining the value potential of IT in HRM, existing IS research predominately studies the impact of IT on HRM. We contribute by examining the reverse impact in three steps. First, we use Thompson\u27s theory of organizations in action to examine the expected impact of the HRM transformation on IT ( to-be situation). Second, we use Kohli and Grover\u27s IT value typology and review 20 years of the publication history ( as-is situation). Finally, we relate expectations to actual review findings. We find that the HRM transformation should lead to a major shift in technology type used in organizations. However, this shift is not recognized yet, which is why our literature review reveals considerable unaddressed value potential of IT in HRM. We finish the paper by outlining IS research avenues in the context of HRM

    Towards Understanding Social Software and Its Impact on Corporate E-Learning Motivation

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    This research combines recent discussions in the cross-disciplinary areas of e-learning, social software, and training motivation. On the one hand, e-learning with its role in a fast paced knowledge society, its potential to revolutionize education and the gap between research and practitioners is already in discussion for years. Discussions are becoming more intense with the rise of social software. On the other hand, human resources, life-long learning, and motivating employees to participate in trainings appear critical to organizations. This research focuses on e-learning in the corporate context and examines the impact of social software features on user motivation based on a review of training motivation literature and on 39 interviews conducted in an international IT services company. Findings suggest that the impact of social software features is still unknown, and that differentiating them by the learner’s needs leads to further insights

    Going beyond operational efficiency in HR using IT – A Literature Review of Human Resources Information Systems

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    Leading academics claim that the management of human resources will be most critical in gaining competitive advantage.Today, the human resources departments (HR) are transforming themselves from an administrative cost-center to an internalpartner delivering additional business value. In this transformation process, information technology (IT) could play a keyrole. Therefore, this paper aims to unfold both the current state of knowledge concerning the value contribution ofinformation systems (IS) for the HR function and approaches that go even beyond operational efficiency. Reviewing nearly8,000 articles, published in the proceedings of eight major IS conferences reveals that in total 35 articles exclusively dealwith the topic of human resources information systems (HRIS) but only very few research approaches show, how HRIScould help to go beyond operational efficiency. Furthermore, the literature analysis identifies that approaches dealing with theIT support for HR planning processes are completely missing so far

    Kommunales Grundwassermonitoring

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    KOMMUNALES GRUNDWASSERMONITORING Kommunales Grundwassermonitoring / Pelzer, Guido (Rights reserved) ( -

    PET/CT-guided biopsies of metabolically active bone lesions: applications and clinical impact

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    Purpose: In a minority of cases a definite diagnosis and stage grouping in cancer patients is not possible based on the imaging information of PET/CT. We report our experience with percutaneous PET/CT-guided bone biopsies to histologically verify the aetiology of hypermetabolic bone lesions. Methods: We retrospectively reviewed the data of 20 consecutive patients who underwent multimodal image-guided bone biopsies using a dedicated PET/CT system in a step-by-step technique. Technical and clinical success rates of PET/CT-guided biopsies were evaluated. Questionnaires were sent to the referring physicians to assess the impact of biopsies on patient management and to check the clinical need for PET/CT-guided biopsies. Results: Clinical indications for biopsy were to histologically verify the aetiology of metabolically active bone lesions without a morphological correlate confirming the suspicion of metastases in 15 patients, to determine the origin of suspected metastases in 3 patients and to evaluate the appropriateness of targeted therapy options in 2 patients. Biopsies were technically successful in all patients. In 19 of 20 patients a definite histological diagnosis was possible. No complications or adverse effects occurred. The result of PET/CT-guided bone biopsies determined a change of the planned treatment in overall 56% of patients, with intramodality changes, e.g. chemotherapy with palliative instead of curative intent, and intermodality changes, e.g. systemic therapy instead of surgery, in 22 and 50%, respectively. Conclusion: PET/CT-guided bone biopsies are a promising alternative to conventional techniques to make metabolically active bone lesions—especially without a distinctive morphological correlate—accessible for histological verification. PET/CT-guided biopsies had a major clinical impact in patients who otherwise cannot be reliably stage grouped at the time of treatment decision

    Head-to-head comparison of CAMPYAIR aerobic culture medium versus standard microaerophilic culture for Campylobacter isolation from clinical samples

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    Campylobacter spp. are considered the most frequent cause of acute gastroenteritis worldwide. However, outside high-income countries, its burden is poorly understood. Limited published data suggest that Campylobacter prevalence in low- and middle-income countries is high, but their reservoirs and age distribution are different. Culturing Campylobacter is expensive due to laboratory equipment and supplies needed to grow the bacterium (e.g., selective culture media, microaerophilic atmosphere, and a 42°C incubator). These requirements limit the diagnostic capacity of clinical laboratories in many resource-poor regions, leading to significant underdiagnosis and underreporting of isolation of the pathogen. CAMPYAIR, a newly developed selective differential medium, permits Campylobacter isolation without the need for microaerophilic incubation. The medium is supplemented with antibiotics to allow Campylobacter isolation in complex matrices such as human feces. The present study aims to evaluate the ability of the medium to recover Campylobacter from routine clinical samples. A total of 191 human stool samples were used to compare the ability of CAMPYAIR (aerobic incubation) and a commercial Campylobacter medium (CASA, microaerophilic incubation) to recover Campylobacter. All Campylobacter isolates were then identified by MALDI-TOF MS. CAMPYAIR showed sensitivity and specificity values of 87.5% (95% CI 47.4%–99.7%) and 100% (95% CI 98%–100%), respectively. The positive predictive value of CAMPYAIR was 100% and its negative predictive value was 99.5% (95% CI 96.7%–99.9%); Kappa Cohen coefficient was 0.93 (95% CI 0.79–1.0). The high diagnostic performance and low technical requirements of the CAMPYAIR medium could permit Campylobacter culture in countries with limited resources

    Upconversion Nanocrystals with High Lanthanide Content: Luminescence Loss by Energy Migration versus Luminescence Enhancement by Increased NIR Absorption

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    Lanthanide-doped upconversion nanoparticles (UCNPs) have attracted a lot of interest due to their benefits in biological applications: They are not suffering from intermittence and provide nearly background-free luminescence. The progress in synthesis nowadays enables access to complex core-shell particles of controlled size and composition. Nevertheless, the frequently used doping ratio dates back to where mostly core-only particles of relatively large size have been studied. Especially at low power excitation as needed in biology, a decrease in particle size leads to a drastic decrease in the upconversion efficiency. An enhancement strategy based on an increased absorption rate of near-infrared light provided by an increase of the sensitizer content, together with the simultaneous blocking of the energy migration pathways to the particle surface, is presented. NaYbF4(20%Er) particles of 8.5 nm diameter equipped with an about 2 nm thick NaYF4 shell show significantly enhanced upconversion luminescence in the red (660 nm) compared to the most commonly used particles with only 20% Yb3+ and 2% Er3+. The impact of size, composition, and core-shell architecture on photophysical properties are studied. The findings demonstrate that an increase in doping rates enables the design of small, bright UCNPs useful for biological applications
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