Dynamic cities and creative clusters

The author focuses on how urban policies and the clustering of creative industries has influenced urban outcomes. The set of creative industries include those with output protectable under some form of intellectual property law. More specifically, this sub-sector encompasses software, multimedia, video games, industrial design, fashion, publishing, and research and development. The cities that form the basis for the empirical investigations are those where policy-induced transitions have been most evident, including Boston; San Francisco; San Diego; Seattle; Austin; Washington, D.C.; Dublin (Ireland); Hong Kong (China); and Bangalore (India). The key research questions are: 1) What types of cities are creative? 2) What locational factors are essential? 3) What are the common urban policy initiatives used by creative cities? The author explores the importance of the external environment for innovation and places it in the larger context of national innovation systems. Based on a study of development in Boston and San Diego, he isolates the factors and policies that have contributed to the local clustering of particular creative industries. In both cities, universities have played a major role in catalyzing the local economy by generating cutting-edge research findings, proactively collaborating with industries, and supplying the needed human capital. In addition, these two cities benefited from the existence of anchor firms and active industry associations that promoted fruitful university-industry links. Many cities in East Asia are aspiring to become the creative hubs of the region. But their investments tend to be heavily biased toward infrastructure provision. Although this is necessary, the heavy emphasis on hardware can lead to underinvestment in developing the talents and skills needed for the emergence of creative industries in these cities.Public Health Promotion,ICT Policy and Strategies,Health Monitoring&Evaluation,Decentralization,Agricultural Knowledge&Information Systems,ICT Policy and Strategies,Health Monitoring&Evaluation,Agricultural Knowledge&Information Systems,Educational Technology and Distance Education,Agricultural Research

Equivariant Holomorphic Morse Inequalities III: Non-Isolated Fixed Points

We prove the equivariant holomorphic Morse inequalities for a holomorphic torus action on a holomorphic vector bundle over a compact Kahler manifold when the fixed-point set is not necessarily discrete. Such inequalities bound the twisted Dolbeault cohomologies of the Kahler manifold in terms of those of the fixed-point set. We apply the inequalities to obtain relations of Hodge numbers of the connected components of the fixed-point set and the whole manifold. We also investigate the consequences in geometric quantization, especially in the context of symplectic cutting.Comment: plain LaTeX, 22 page

Shanghai rising in a globalizing world

In a globalizing world, cities at or near the apex of the international urban hierarchy are among the favored few--New York, London, and Tokyo--that have acquired large economic, cultural, and symbolic roles. Among a handful of regions that aspire to such a role--such as Hong Kong, Miami, and Sao Paulo--Shanghai has reasonable long-term prospects. If the Chinese economy can sustain its growth rate, it will rival the United States in a few decades. And if Shanghai can sustain its preeminence in China, it is the Asian city most likely to become a global center. The authors explore the makings of a world city, identify ingredients essential for that status, indicate national and municipal policies that may set Shanghai on the path to being a global city, and show how such policies are being implemented. As urbanization continues, the authors say, and as information technology and finance-related service activities take on even more importance, the number of regional and global centers could increase, but only if they satisfy some exacting requirements. Shanghai's chances, for example, depend on the extent to which China opens up and on a host of municipal policies--policies that emphasize Shanghai's industrial strength, substantially enlarge its base of information technology and producer services, ensure an adequate supply of skills, expand available housing and infrastructure enough to meet demand, and improve the quality of life.Decentralization,Banks&Banking Reform,Municipal Financial Management,Payment Systems&Infrastructure,Environmental Economics&Policies,Environmental Economics&Policies,ICT Policy and Strategies,Public Sector Economics&Finance,Banks&Banking Reform,Municipal Financial Management

Study on Fund Raising Means for China's Railways

The existing financing resources of construction fund for China s railways are presented in the first section of this paper. In the next section, The impacts and restrictions of the funding raising means were analyzed and a proposal of reforming the existing financing means was raised on the base of these analyses. The proposal included the following contents: construction funds for the railroads with different functions should be raised by using different financing means. The paper focused on means of fund raising for regional railway construction projects. It stated in detail how this kind of projects would attract social capital by relying on government supporting policies through the reform of the railway system. For instance, what kinds of projects are possible to attract direct international investments; what kind of projects can use BOT method and how to introduce it; what countermeasures should be taken for the deficit breach lines, etc.Institute of Transport and Logistics Studies. Faculty of Economics and Business. The University of Sydne

Study on Fund Raising Means for China's Railways

The existing financing resources of construction fund for China s railways are presented in the first section of this paper. In the next section, The impacts and restrictions of the funding raising means were analyzed and a proposal of reforming the existing financing means was raised on the base of these analyses. The proposal included the following contents: construction funds for the railroads with different functions should be raised by using different financing means. The paper focused on means of fund raising for regional railway construction projects. It stated in detail how this kind of projects would attract social capital by relying on government supporting policies through the reform of the railway system. For instance, what kinds of projects are possible to attract direct international investments; what kind of projects can use BOT method and how to introduce it; what countermeasures should be taken for the deficit breach lines, etc.Institute of Transport and Logistics Studies. Faculty of Economics and Business. The University of Sydne

Compact hollow waveguide mid-infrared gas sensor for simultaneous measurements of ambient CO2 and water vapor

A compact, sensitive and stable hollow waveguide (HWG) mid-infrared gas sensor, based on gas absorption lines using wavelength modulation spectroscopy with a second harmonic (WMS-2f) detection scheme, was developed for simultaneous measurements of ambient CO 2 and water vapor. Optimization of the laser modulation parameters and pressure parameter in the HWG are performed to improve the strength of the WMS-2f signal and hence the detection limit, where 14.5-time for CO 2 and 8.5-time for water vapor improvement in system detection limit is achieved compared to those working at 1 atm. The stability of the sensor has been improved significantly by optimizing environmental disturbances, incoupling alignment of the HWG and laser scanning frequency. An Allan variance analysis shows detection limit of the developed sensor of ~3 ppmv for CO 2 and 0.018% for water vapor, which correspond to an absorbance of 2.4 × 10 -5 and 2.7 × 10 -5 , with a stability time of 160 s, respectively. Ambient CO 2 and water vapor measurement have been performed in two days in winter and spring separately. The measurement precision is further improved by applying a Kalman adaptive filter. The HWG gas sensor demonstrates the ability in environmental monitoring and the potential to be used in other areas, such as industrial production and biomedical diagnosis

The master cell cycle regulator APC-Cdc20 regulates ciliary length and disassembly of the primary cilium

The primary cilium has an important role in signaling; defects in structure are associated with a variety of human diseases. Much of the most basic biology of this organelle is poorly understood, even basic mechanisms, such as control of growth and resorption. We show that the activity of the anaphase-promoting complex (APC), an E3 that regulates the onset of anaphase, destabilizes axonemal microtubules in the primary cilium. Furthermore, the metaphase APC co-activator, Cdc20, is specifically recruited to the basal body of primary cilia. Inhibition of APC-Cdc20 activity increases the ciliary length, while overexpression of Cdc20 suppresses cilium formation. APC-Cdc20 activity is required for the timely resorption of the cilium after serum stimulation. In addition, APC regulates the stability of axonemal microtubules through targeting Nek1, the ciliary kinase, for proteolysis. These data demonstrate a novel function of APC beyond cell cycle control and implicate critical role of ubiquitin-mediated proteolysis in ciliary disassembly. DOI: http://dx.doi.org/10.7554/eLife.03083.00