7,167 research outputs found
Effects of Core-Hole Screening on Spin-Polarised Auger Spectra from Ferromagnetic Nickel
We calculate the spin- and temperature-dependent local density of states for
ferromagnetic Ni in the presence of a core hole at a distinguished site in the
lattice. Correlations among the valence electrons and between valence and core
electrons are described within a multi-band Hubbard model which is treated by
means of second-order perturbation theory around the Hartree-Fock solution. The
core-hole potential causes strong screening effects in the Ni valence band. The
local magnetic moment is found to be decreased by a factor 5-6. The
consequences for the spin polarisation of CVV Auger electrons are discussed.Comment: LaTeX, 4 pages, 1 eps figure included, Acta Physica Polonica A (in
press), Physics of Magnetism '99 (Poznan, Poland
Treatment, complications, and outcomes of metastatic disease of the spine: From Patchell to PROMIS
Treatment, complications, and outcomes of metastatic disease of the spine: From Patchell to PROMIS
Pulse EPR measurements of intramolecular distances in a TOPP-labeled transmembrane peptide in lipids.
We present the performance of nanometer-range pulse electron paramagnetic resonance distance measurements (pulsed electron-electron double resonance/double electron-electron resonance, PELDOR/DEER) on a transmembrane WALP24 peptide labeled with the semirigid unnatural amino acid 4-(3,3,5,5-tetra-methyl-2,6-dioxo-4-oxylpiperazin-1-yl)-l-phenylglycine (TOPP). Distances reported by the TOPP label are compared to the ones reported by the more standard MTSSL spin label, commonly employed in protein studies. Using high-power pulse electron paramagnetic resonance spectroscopy at Q-band frequencies (34 GHz), we show that in contrast to MTSSL, our label reports one-peak, sharp (Δr ≤ 0.4 nm) intramolecular distances. Orientational selectivity is not observed. When spin-labeled WALP24 was inserted in two representative lipid bilayers with different bilayer thickness, i.e., DMPC and POPC, the intramolecular distance reported by TOPP did not change with the bilayer environment. In contrast, the distance measured with MTSSL was strongly affected by the hydrophobic thickness of the lipid. The results demonstrate that the TOPP label is well suited to study the intrinsic structure of peptides immersed in lipids
The A-theoretic Farrell–Jones conjecture for virtually solvable groups
We prove the A -theoretic Farrell–Jones conjecture for virtually solvable groups. As a corollary, we obtain that the conjecture holds for S -arithmetic groups and lattices in almost connected Lie groups
The genomics of neonatal abstinence syndrome
Significant variability has been observed in the development and severity of neonatal abstinence syndrome (NAS) among neonates exposed to prenatal opioids. Since maternal opioid dose does not appear to correlate directly with neonatal outcome, maternal, placental, and fetal genomic variants may play important roles in NAS. Previous studies in small cohorts have demonstrated associations of variants in maternal and infant genes that encode the μ-opioid receptor (OPRM1), catechol-O-methyltransferase (COMT), and prepronociceptin (PNOC) with a shorter length of hospital stay and less need for treatment in neonates exposed to opioids in utero. Consistently falling genomic sequencing costs and computational approaches to predict variant function will permit unbiased discovery of genomic variants and gene pathways associated with differences in maternal and fetal opioid pharmacokinetics and pharmacodynamics and with placental opioid transport and metabolism. Discovery of pathogenic variants should permit better delineation of the risk of developing more severe forms of NAS. This review provides a summary of the current role of genomic factors in the development of NAS and suggests strategies for further genomic discovery
How does the local wind field control the aerosol distribution in coastal Dronning Maud Land?
Atmospheric circulation patterns and chemical concentrations in firn cores are highly related to each other. Atmospheric winds transport aerosols like sea salt and mineral dust over the globe and redistribute them. Because of this, it is possible to reconstruct atmospheric circulation bringing aerosol to Antarctica by analyzing chemical impurities in firn and ice. With these analyses, the gap caused by sparse atmospheric measurements can be filled and this knowledge can then be used to improve the understanding of local and global circulation patterns.Due to a very high accumulation rate (~600 kg/m²*a), coastal Dronning Maud Land (CDML) is a perfect site to conduct these studies.Here, the upper 6m of two firn cores drilled on Halvfaryggen and Sörasen (covering the time interval from 2002- 2007) were analyzed on ionic concentrations. This data was then contrasted to measurements from the air chemistry laboratories at Neumayer (NM) and Kohnenstation (KS), and synoptic measurements from automatic weather stations (distributed in CDML and at NM).The analyses show very different results: Sea salt ions (e.g. Na+) are higher correlated to ions measured in aerosol samples at the air chemistry laboratory at KS than to the one located at NM. In contrast, ions representing mineral dust (e.g. nss-Ca2+) only have a weak correlation over the whole area and time period. Accordingly, the deposition of aerosol is highly dependent on its origin and the topography in coastal Antarctica suggesting different transport pathways for sea level and higher altitude sites
How to Think, Say, or Do Precisely the Worst Thing For Any Occasion
In slapstick comedy, the worst thing that could happen usually does: The person with a sore toe manages to stub it, sometimes twice. Such errors also arise in daily life, and research traces the tendency to do precisely the worst thing to ironic processes of mental control. These monitoring processes keep us watchful for errors of thought, speech, and action and enable us to avoid the worst thing in most situations, but they also increase the likelihood of such errors when we attempt to exert control under mental load (stress, time pressure, or distraction). Ironic errors in attention and memory occur with identifiable brain activity and prompt recurrent unwanted thoughts; attraction to forbidden desires; expression of objectionable social prejudices; production of movement errors; and rebounds of negative experiences such as anxiety, pain, and depression. Such ironies can be overcome when effective control strategies are deployed and mental load is minimized.Psycholog
An Analysis of the Relationship between Risk Alignment and Cost Performance
This thesis investigates the relationship between risk alignment and cost performance in DoD procurement. Both the government and the contractor conduct independent assessments of the perceived risk in a contract. The results of inaccurate risk assessments are undesirable consequences, one of which is the inability to achieve cost targets. If both the contractor\u27s and the government\u27s perceptions of risk are in alignment with the actual risk involved in a contract, then we would expect minimal impact. If, however, either or both parties fail to accurately assess the actual risk, then we would expect consequences, such as cost overrun/underrun. The level of cost overrun/underrun can be determined by examining the level of alignment between the actual risk and each party\u27s perception of the risk. Results indicate a significant potential for cost growth when both the government and the contractor underestimate the actual risk. In this context, the level of cost growth experienced on a contract is a reflection of the adequacy of the parties\u27 risk assessments. Failure to accurately assess risk could result in a lack of sufficient \u27safeguards\u27 necessary to help mitigate the damaging effects of risk inherent in a contract
- …