11,308 research outputs found
Antioxidants that protect mitochondria reduce interleukin-6 and oxidative stress, improve mitochondrial function, and reduce biochemical markers of organ dysfunction in a rat model of acute sepsis
Funding This study was funded by the Medical Research Council (Grant number G0800149). Research material from this study is not available. Acknowledgement We are very grateful to Dr Robin A.J. Smith, Department of Chemistry, University of Otago, Dunedin, New Zealand, for the generous gifts of MitoE and MitoQ, without which this work would not have been possible.Peer reviewedPublisher PD
Pharmacological activation of endogenous protective pathways against oxidative stress under conditions of sepsis
Funding The study was funded entirely by institutional funds.Peer reviewedPostprin
Obstructions to embeddability into hyperquadrics and explicit examples
We give series of explicit examples of Levi-nondegenerate real-analytic
hypersurfaces in complex spaces that are not transversally holomorphically
embeddable into hyperquadrics of any dimension. For this, we construct
invariants attached to a given hypersurface that serve as obstructions to
embeddability. We further study the embeddability problem for real-analytic
submanifolds of higher codimension and answer a question by Forstneri\v{c}.Comment: Revised version, appendix and references adde
Correlation in the transition metal based Heusler compounds CoMnSi and CoFeSi
Half-metallic ferromagnets like the full Heusler compounds with formula
XYZ are supposed to show an integer value of the spin magnetic moment.
Calculations reveal in certain cases of X = Co based compounds non-integer
values, in contrast to experiments. In order to explain deviations of the
magnetic moment calculated for such compounds, the dependency of the electronic
structure on the lattice parameter was studied theoretically. In local density
approximation (LDA), the minimum total energy of CoFeSi is found for the
experimental lattice parameter, but the calculated magnetic moment is about 12%
too low. Half-metallic ferromagnetism and a magnetic moment equal to the
experimental value of are found, however, only after increasing the
lattice parameter by more than 6%.
To overcome this discrepancy, the LDA scheme was used to respect on-site
electron correlation in the calculations. Those calculations revealed for
CoFeSi that an effective Coulomb-exchange interaction in the
range of about 2eV to 5eV leads to half-metallic ferromagnetism and the
measured, integer magnetic moment at the measured lattice parameter. Finally,
it is shown in the case of CoMnSi that correlation may also serve to
destroy the half-metallic behavior if it becomes too strong (for CoMnSi
above 2eV and for CoFeSi above 5eV). These findings indicate that on-site
correlation may play an important role in the description of Heusler compounds
with localized moments.Comment: submitted to Phys. Rev.
Risk Assessment of the potential impacts of seismic air gun surveys on marine finfish and invertebrates in Western Australia
Seismic surveys have the potential to affect marine life, including commercially and recreationally important finfish and invertebrate species and their prey. There is, however, considerable uncertainty around the degree of impact and relevant pressure-response pathways across the different taxonomic groups
Development and Characterisation of a Gas System and its Associated Slow-Control System for an ATLAS Small-Strip Thin Gap Chamber Testing Facility
A quality assurance and performance qualification laboratory was built at
McGill University for the Canadian-made small-strip Thin Gap Chamber (sTGC)
muon detectors produced for the 2019-2020 ATLAS experiment muon spectrometer
upgrade. The facility uses cosmic rays as a muon source to ionise the quenching
gas mixture of pentane and carbon dioxide flowing through the sTGC detector. A
gas system was developed and characterised for this purpose, with a simple and
efficient gas condenser design utilizing a Peltier thermoelectric cooler (TEC).
The gas system was tested to provide the desired 45 vol% pentane concentration.
For continuous operations, a state-machine system was implemented with alerting
and remote monitoring features to run all cosmic-ray data-acquisition
associated slow-control systems, such as high/low voltage, gas system and
environmental monitoring, in a safe and continuous mode, even in the absence of
an operator.Comment: 23 pages, LaTeX, 14 figures, 4 tables, proof corrections for Journal
of Instrumentation (JINST), including corrected Fig. 8b
An Investigation of a Supersonic Aircraft Configuration Having a Tapered Wing with Circular-arc Section and 40 Degree Sweepback : a Pressure-distribution Study of the Aerodynamic Characteristics of the Wing at Mach Number 1.40
Epidemiological Interactions between Urogenital and Intestinal Human Schistosomiasis in the Context of Praziquantel Treatment across Three West African Countries
© 2015 Knowles et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. The attached file is the published version of the article
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