Writing Illinois: the Prairie, Lincoln, and Chicago

Review of: Writing Illinois: The Prairie, Lincoln, and Chicago. Hurt, James

Writing Illinois: the Prairie, Lincoln, and Chicago

Review of: Writing Illinois: The Prairie, Lincoln, and Chicago. Hurt, James

Public Support for Pro-Choice Abortion Policies in the Nation and States: Changes and Stability After the \u3cem\u3eRoe\u3c/em\u3e and \u3cem\u3eDoe\u3c/em\u3e Decisions

The Supreme Court, according to the legendary Mr. Dooley, follows the election returns. In 1973, the Court\u27s two landmark decisions, Roe v. Wade and Doe v. Bolton, struck down statutes in the forty-six states where abortions were not permitted under any circumstances or were allowed only to save the life of the woman during the first three months of pregnancy. There had been a considerable increase in the level of support for the pro-choice position among the public in the few years preceding Roe and Doe. But did the decisions themselves lead to even more public support for that position? What variations do we find among the states and where has the increase in public support for the pro-choice position seemed the most dramatic? Finally, what has been the impact of the abortion controversy on the political process? We shall examine these questions here and suggest some tentative answers. First, we shall consider the available national poll evidence. Second, we shall examine variations in political opinion on abortion policies in the states. Finally, we shall examine the abortion controversy as it has affected legislative decision making and electoral politics. When we consider the variations among the states, we shall present estimates of state public opinion on abortion policy through a computer simulation technique, developed by the second author and refined jointly by us, which permits us to get approximate figures on state opinions from national surveys

Operating experience of a 50kwth methane chemical looping reactor

Chemical Looping Combustion (CLC) has the potential to efficiently capture CO2 from the combustion of fossil fuels at an affordable price. CLC is a process that produces a flue gas primarily consisting of CO2 and H2O. The CO2 can be easily separated and captured by condensing the H2O, similar to an oxy-fuel process. Although the process looks promising on paper, the challenge is to make chemical looping a reality by demonstrating that the process can work economically. To help achieve this goal, the US Department of Energy’s (DOE) National Energy Technology Laboratory (NETL), has constructed and tested a 50kWth chemical looping reactor (CLR). The general arrangement of the process consists of a bubbling fluidized bed fuel reactor and a fluidized bed/riser air reactor. Three different metal oxide based oxygen carriers have been successfully tested during week-long test campaigns; a hematite ore, promoted hematite ore, and a manufactured copper based oxygen carrier. These three carriers have demonstrated various levels of performance including conversion of natural gas to CO2 and durability. The goal of these tests is to better understand real process metrics so that appropriate economic analysis can be performed

Fundamentals of rotating fluidized beds and application to particle separation

Rotating fluidized beds provide unique opportunities to exploit fluidization under higher particle forces. The centripetal force in a rotating bed is typically on the order of 10 times the force of gravity. Since the force keeping the particles in the unit is larger, the drag force can also be larger, allowing for higher gas velocities. This operating regime provides opportunities for higher mass transfer, heat transfer, gas throughput, and bubble suppression. One application for using a rotating fluidized bed in in Chemical Looping Combustion (CLC). When solid fuels are used, oxygen carrier and ash are mixed in the process. In order to maintain high carbon capture efficiencies and recyclability of the oxygen carrier, the ash needs to be separated from the oxygen carrier. This separation can be done aerodynamically since the oxygen carrier is larger and heavier then the ash. It is theorized that rotating fluidized beds could improve the separation process efficiency and throughput as compared to conventional fluidized beds. A 43cm diameter, 2.5cm thick rotating fluidized bed has been designed and constructed to investigate the application of the rotating fluidized beds to particle separation. A series of experiments have been performed to investigate the separation of glass beads (coal ash analog) from a typical chemical looping oxygen carrier. These experiments demonstrate the use of a rotating fluidized bed for particle separation as well as investigate the operational parameters that influence the efficiency of separation

Mobile test fixture system for use in a thermal vacuum facility

A turnkey thermal vacuum facility is discussed. A system is described that integrates five major subsystems including the transporters, multiplexers, a thermal shrouded test fixture, a thermal isolation system and an internal utility distribution system into a mobile test fixture system. This concept allows the spacecraft to be mounted outside of the chamber. Instrumentation and checkout of the spacecraft and its instrumentation is accomplished at this station. The spacecraft, which is still mated to the test fixture, is then moved into the chamber using an air transporter system

A novel mammalian expression system derived from components coordinating nicotine degradation in arthrobacter nicotinovorans pAO1

We describe the design and detailed characterization of 6-hydroxy-nicotine (6HNic)-adjustable transgene expression (NICE) systems engineered for lentiviral transduction and in vivo modulation of angiogenic responses. Arthrobacter nicotinovorans pAO1 encodes a unique catabolic machinery on its plasmid pAO1, which enables this Gram-positive soil bacterium to use the tobacco alkaloid nicotine as the exclusive carbon source. The 6HNic-responsive repressor-operator (HdnoR-ONIC) interaction, controlling 6HNic oxidase production in A.nicotinovorans pAO1, was engineered for generic 6HNic-adjustable transgene expression in mammalian cells. HdnoR fused to different transactivation domains retained its ONIC-binding capacity in mammalian cells and reversibly adjusted transgene transcription from chimeric ONIC-containing promoters (PNIC; ONIC fused to a minimal eukaryotic promoter [Pmin]) in a 6HNic-responsive manner. The combination of transactivators containing various transactivation domains with promoters differing in the number of operator modules as well as in their relative inter-ONIC and/or ONIC-Pmin spacing revealed steric constraints influencing overall NICE regulation performance in mammalian cells. Mice implanted with microencapsulated cells engineered for NICE-controlled expression of the human glycoprotein secreted placental alkaline phosphatase (SEAP) showed high SEAP serum levels in the absence of regulating 6HNic. 6HNic was unable to modulate SEAP expression, suggesting that this nicotine derivative exhibits control-incompatible pharmacokinetics in mice. However, chicken embryos transduced with HIV-1-derived self-inactivating lentiviral particles transgenic for NICE-adjustable expression of the human vascular endothelial growth factor 121 (VEGF121) showed graded 6HNic response following administration of different 6HNic concentrations. Owing to the clinically inert and highly water-soluble compound 6HNic, NICE-adjustable transgene control systems may become a welcome alternative to available drug-responsive homologs in basic research, therapeutic cell engineering and biopharmaceutical manufacturin

A novel mammalian expression system derived from components coordinating nicotine degradation in arthrobacter nicotinovorans pAO1

We describe the design and detailed characterization of 6-hydroxy-nicotine (6HNic)-adjustable transgene expression (NICE) systems engineered for lentiviral transduction and in vivo modulation of angiogenic responses. Arthrobacter nicotinovorans pAO1 encodes a unique catabolic machinery on its plasmid pAO1, which enables this Gram-positive soil bacterium to use the tobacco alkaloid nicotine as the exclusive carbon source. The 6HNic-responsive repressor-operator (HdnoR-O(NIC)) interaction, controlling 6HNic oxidase production in A.nicotinovorans pAO1, was engineered for generic 6HNic-adjustable transgene expression in mammalian cells. HdnoR fused to different transactivation domains retained its O(NIC)-binding capacity in mammalian cells and reversibly adjusted transgene transcription from chimeric O(NIC)-containing promoters (P(NIC); O(NIC) fused to a minimal eukaryotic promoter [P(min)]) in a 6HNic-responsive manner. The combination of transactivators containing various transactivation domains with promoters differing in the number of operator modules as well as in their relative inter-O(NIC) and/or O(NIC)-P(min) spacing revealed steric constraints influencing overall NICE regulation performance in mammalian cells. Mice implanted with microencapsulated cells engineered for NICE-controlled expression of the human glycoprotein secreted placental alkaline phosphatase (SEAP) showed high SEAP serum levels in the absence of regulating 6HNic. 6HNic was unable to modulate SEAP expression, suggesting that this nicotine derivative exhibits control-incompatible pharmacokinetics in mice. However, chicken embryos transduced with HIV-1-derived self-inactivating lentiviral particles transgenic for NICE-adjustable expression of the human vascular endothelial growth factor 121 (VEGF(121)) showed graded 6HNic response following administration of different 6HNic concentrations. Owing to the clinically inert and highly water-soluble compound 6HNic, NICE-adjustable transgene control systems may become a welcome alternative to available drug-responsive homologs in basic research, therapeutic cell engineering and biopharmaceutical manufacturing