8,064 research outputs found

    The Problem: Low Achieving Districts and Low Performing Boards

    Get PDF
    Effective school districts maintain superintendent and school board collegiality which can foster success and connectedness among members. Delagardelle and Alsbury (2008) found that superintendents and board members are not consistent in their perceptions about the work the board does, and Glass (2007) found that states do not require boards to undergo evaluation for effectiveness. In the current study, 115 board meetings were observed using the School Board Video Project (SBVP) survey, which was created in 2012 by researchers to uncover school board meetings’ effectiveness. MANOVA, Univariate ANOVA, and Pearson Chi-Square test results revealed significant differences between low-, medium-, and high-performing districts’ school board meetings. Evidence indicated that low-performing districts’ board meetings were: less orderly; had less time spent on student achievement; lacked respectful and attentive engagement across speakers; had board meeting members who seemed to advance their own agenda; had less effective working relationships among the governance team; had fewer board members who relied on the superintendent for advice and input; had one member, other than the board president, stand out for taking excessive time during meetings; and did not focus on policy items as much as high- and medium-performing school districts. The research concluded that more school board members from low-performing districts needed training to improve their effectiveness. Furthermore, highly refined and target-enhanced school board training programs might lead to lasting governance success and more effective teaming that could improve district, and ultimately, student achievement

    Critical Factors Affecting Job Offers for New MIS Graduates

    Get PDF
    Due to the sharp IT budget cuts in corporate America, the slowing economy, and the offshore outsourcing trend, job opportunities for MIS graduates have become scarcer in recent years. In addition to having good academic performance, MIS students have adopted aggressive approaches, such as MIS internships, double majors, and more technical course work, to securing employment. However, research on the critical factors affecting MIS full-time job offers has not received enough attention, and little empirical research is currently available. This study intends to explore this important issue using a survey research methodology. 742 seniors majoring in MIS were surveyed in three different US universities and 213 seniors actually participated in the survey. The critical factors identified in this study include internship experience, the nature of internship experience, double majors, the time when students declare their MIS majors, grade point average, and gender difference. The research findings in this study indicate that student GPA, networking-oriented internship, and double majors are identified as the key items influencing MIS full time job offers

    The Vehicle, April 1959, Vol. 1 no. 1

    Get PDF
    Vol. 1, No. 1 Table of Contents Aunt OraHelen Leepage 3 Ethnocentrismpage 7 FashionsLinda Lyonspage 7 On Giving Up Auden in DespairHelen Leepage 8 The Vagaries of ComplianceHelen Leepage 8 The StormJean Nightingalepage 9 Sonnet to SubjectWayne Nelmspage 9 The Killing of Mr. KitAl Brookspage 10 ShortsC.E.S.page 16https://thekeep.eiu.edu/vehicle/1000/thumbnail.jp

    Microbial sphingomyelinase induces RhoA-mediated reorganization of the apical brush border membrane and is protective against invasion

    Get PDF
    The apical brush border membrane (BBM) of intestinal epithelial cells forms a highly structured and dynamic environmental interface that serves to regulate cellular physiology and block invasion by intestinal microbes and their products. How the BBM dynamically responds to pathogenic and commensal bacterial signals can define intestinal homeostasis and immune function. We previously found that in model intestinal epithelium, the conversion of apical membrane sphingomyelin to ceramide by exogenous bacterial sphingomyelinase (SMase) protected against the endocytosis and toxicity of cholera toxin. Here we elucidate a mechanism of action by showing that SMase induces a dramatic, reversible, RhoA-dependent alteration of the apical cortical F-actin network. Accumulation of apical membrane ceramide is necessary and sufficient to induce the actin phenotype, and this coincides with altered membrane structure and augmented innate immune function as evidenced by resistance to invasion by Salmonella

    Missense-depleted regions in population exomes implicate ras superfamily nucleotide-binding protein alteration in patients with brain malformation.

    Get PDF
    Genomic sequence interpretation can miss clinically relevant missense variants for several reasons. Rare missense variants are numerous in the exome and difficult to prioritise. Affected genes may also not have existing disease association. To improve variant prioritisation, we leverage population exome data to identify intragenic missense-depleted regions (MDRs) genome-wide that may be important in disease. We then use missense depletion analyses to help prioritise undiagnosed disease exome variants. We demonstrate application of this strategy to identify a novel gene association for human brain malformation. We identified de novo missense variants that affect the GDP/GTP-binding site of ARF1 in three unrelated patients. Corresponding functional analysis suggests ARF1 GDP/GTP-activation is affected by the specific missense mutations associated with heterotopia. These findings expand the genetic pathway underpinning neurologic disease that classically includes FLNA. ARF1 along with ARFGEF2 add further evidence implicating ARF/GEFs in the brain. Using functional ontology, top MDR-containing genes were highly enriched for nucleotide-binding function, suggesting these may be candidates for human disease. Routine consideration of MDR in the interpretation of exome data for rare diseases may help identify strong genetic factors for many severe conditions, infertility/reduction in reproductive capability, and embryonic conditions contributing to preterm loss

    Ultra-short pulses in linear and nonlinear media

    Get PDF
    We consider the evolution of ultra-short optical pulses in linear and nonlinear media. For the linear case, we first show that the initial-boundary value problem for Maxwell's equations in which a pulse is injected into a quiescent medium at the left endpoint can be approximated by a linear wave equation which can then be further reduced to the linear short-pulse equation. A rigorous proof is given that the solution of the short pulse equation stays close to the solutions of the original wave equation over the time scales expected from the multiple scales derivation of the short pulse equation. For the nonlinear case we compare the predictions of the traditional nonlinear Schr\"odinger equation (NLSE) approximation which those of the short pulse equation (SPE). We show that both equations can be derived from Maxwell's equations using the renormalization group method, thus bringing out the contrasting scales. The numerical comparison of both equations to Maxwell's equations shows clearly that as the pulse length shortens, the NLSE approximation becomes steadily less accurate while the short pulse equation provides a better and better approximation

    Generic Airspace Research Phase 5 Report

    Get PDF
    Human-in-the-loop testing was completed to assess the subjective preferences, usage, and operational benefits of Integrated and Separated Controller Information Tools (CITs) in support of Generic Airspace Research. Participants controlled traffic in in a busy, high altitude sector with the aid of the CITs. When the participants were asked which CIT that they preferred to use, they overwhelmingly chose the integrated version of the CIT. The primary reason for this seemed to be that it allowed participants to remain focused on the traffic situation, whereas the Standalone CIT required them to focus their attention for short periods away from the radar presentation. In contrast to their preference, there were little or no differences in the CIT usage and the operational differences. There were similar numbers of losses of separation and participants accessed each CIT equally. Although the information accessed was the similar for the two conditions, participants actively turned off the data on the Integrated CIT, presumably to reduce the clutter on the radar scope. Further work is needed to isolate which information can and should be available to controllers in the Integrated vs. Standalone format

    Spacecraft Escape Capsule

    Get PDF
    A report discusses the Gumdrop capsule a conceptual spacecraft that would enable the crew to escape safely in the event of a major equipment failure at any time from launch through atmospheric re-entry. The scaleable Gumdrop capsule would comprise a command module (CM), a service module (SM), and a crew escape system (CES). The CM would contain a pressurized crew environment that would include avionic, life-support, thermal control, propulsive attitude control, and recovery systems. The SM would provide the primary propulsion and would also supply electrical power, life-support resources, and active thermal control to the CM. The CES would include a solid rocket motor, embedded within the SM, for pushing the CM away from the SM in the event of a critical thermal-protection-system failure or loss of control. The CM and SM would normally remain integrated with each other from launch through recovery, but could be separated using the CES, if necessary, to enable the safe recovery of the crew in the CM. The crew escape motor could be used, alternatively, as a redundant means of de-orbit propulsion for the CM in the event of a major system failure in the SM
    • …
    corecore