500 research outputs found

    MACHINERY COSTS AND INFLATION

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    This article addresses (1) the differences in machinery cost estimating techniques, particularly for depreciation and opportunity cost, and (2) the necessary modifications in cost estimating techniques to account for the changing monetary base under inflation. The conditions under which capital budgeting and traditional budgeting differ are examined on a before tax and after tax basis, with and without inflation. The variations in cost estimates depending upon techniques, and with and without inflation, are compared.Agricultural Finance,

    Book Review: Juridical Positivism and Human Rights

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    Book Revie

    Probabilistic estimates of climate change impacts on UK water resources

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    Climate change will increase temperatures and change rainfall across the UK. In turn, this will modify patterns of river flow and groundwater recharge, affecting the availability of water. There have been many studies of the impact of climate change on river flows in the UK, but coverage has been uneven and methods have varied. Consequently, it has been very difficult to compare different locations and hard to identify appropriate adaptation responses

    Low flow response surfaces for drought decision support: a case study from the UK

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    Droughts are complex natural hazards, and planning future management is complicated by the difficulty of projecting future drought and low flow conditions. This paper demonstrates the use of a response surface approach to explore the hydrological behavior of catchments under a range of possible future conditions. Choosing appropriate hydrological metrics ensures that the response surfaces are relevant to decision-making. Examples from two contrasting English catchments show how low flows in different catchments respond to changes in rainfall and temperature. In an upland western catchment, the Mint, low flows respond most to rainfall and temperature changes in summer, but in the groundwater dominated catchment of the Thet, changes in spring rainfall have the biggest impact on summer flows. Response surfaces are useful for understanding long-term changes, such as those projected in climate projections, but they may also prove useful in drought event management, where possible future conditions can be plotted onto the surface to understand the range of conditions the manager faces. Developing effective response surfaces requires considerable involvement and learning from catchment decision-makers at an early stage, and this should be considered in any planned application

    INCORPORATING SAFETY-FIRST CONSTRAINTS IN LINEAR PROGRAMMING PRODUCTION MODELS

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    A recent survey indicated that many procedures view risk in a safety-first context. Traditional methods used to impose safety-first constraints in optimization models have often been difficult to implement. This is particularly true when endogenous decisions affect the distribution of the chance-constrained random variable. This paper presents a method whereby probabilistic constraints can be easily imposed upon finitely discrete random variables. The procedure uses a linear version of the lower partial moment stochastic inequality. The resulting solutions are somewhat conservative but are less so than the results using the previously published mean income-absolute deviation stochastic inequality.Production Economics, Research Methods/ Statistical Methods,

    PERFORMANCE OF RISK-INCOME MODELS OUTSIDE THE ORIGINAL DATA SET

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    Selected risk programming solutions (i.e., profit maximization, Target-MOTAD, and MOTAD) are tested in an economic environment outside the data set from which they were developed. Specifically, solutions are derived from either a longer 10-year (1965-74) or shorter 6-year estimation period (1969-74), and then, they are tested for consistent risk-income characteristics over a later 10-year period (1975-84). Risk solutions estimated from earlier periods perform well in the later test period in spite of different economic conditions between time periods. However, favorable performance may be related to the specific example used in this analysis. Further testing for other farm situations is needed before general conclusions can be reached.Risk and Uncertainty,

    A Naturally-Occurring Histone Acetyltransferase Inhibitor Derived from Garcinia indica Impairs Newly Acquired and Reactivated Fear Memories

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    The study of the cellular and molecular mechanisms underlying the consolidation and reconsolidation of traumatic fear memories has progressed rapidly in recent years, yet few compounds have emerged that are readily useful in a clinical setting for the treatment of anxiety disorders such as post-traumatic stress disorder (PTSD). Here, we use a combination of biochemical, behavioral, and neurophysiological methods to systematically investigate the ability of garcinol, a naturallyoccurring histone acetyltransferase (HAT) inhibitor derived from the rind of the fruit of the Kokum tree (Garcina indica), to disrupt the consolidation and reconsolidation of Pavlovian fear conditioning, a widely studied rodent model of PTSD. We show that local infusion of garcinol into the rat lateral amygdala (LA) impairs the training and retrieval-related acetylation of histone H3 in the LA. Further, we show that either intra-LA or systemic administration of garcinol within a narrow window after either fear conditioning or fear memory retrieval significantly impairs the consolidation and reconsolidation of a Pavlovian fear memory and associated neural plasticity in the LA. Our findings suggest that a naturally-occurring compound derived from the diet that regulates chromatin function may be useful in the treatment of newly acquired or recently reactivated traumatic memories
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